Pharm Mt 1 Part I
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Describe how mannitol with cisplatinum leads to altered excretion.
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Pharm MT 1 Part I is a quiz designed to assess knowledge in pharmacology, focusing on drug interactions, pharmacokinetics, and pharmacodynamics. It evaluates understanding of how drugs are absorbed, metabolized, and their effects, which is crucial for medical students and professionals.
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- 2.
Describe what is considered an 'empty stomach'
- 3.
Descibe and give examples of the difference between physiological and psychological drug dependence.
- 4.
Proparcaine is considered a type of treatment pharmacotherapeutic because it treats the adverse effects of tropicamide.
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True
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False
Correct Answer
A. FalseExplanation
Proparcaine is a prophylactic because it PREVENTS the adverse effects od dilating drops
Other prophylactics: flu shot
(pg.4)Rate this question:
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- 5.
In terms of tolerance, a drug has ____________ effectiveness over time with ___________ use.
Correct Answer
decreased; repeatedExplanation
pg. 5Rate this question:
- 6.
Check ALL processes that correspond to pharmacokinetics:
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How drugs are absorbed in the body
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Properties of drug effects
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How drugs are biotransformed
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How drugs are excreted in from the body
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The relationship between genetic factors and drug response
Correct Answer(s)
A. How drugs are absorbed in the body
A. How drugs are biotransformed
A. How drugs are excreted in from the bodyExplanation
pg.5Rate this question:
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- 7.
Which of the following does NOT correspond to pharmacodynamics?
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Time to onset of action
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Duration of action
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How a drug is metabolized in the body
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Expected time for drug clearance
Correct Answer
A. How a drug is metabolized in the bodyExplanation
Pharmacodynamics--> think TIME
Pharmacokinetics --> think HOW the body deals with/processes a drug
Pharmacogenetics --> relationship btwn genetic factors and drug response
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- 8.
Which of the following describes drug idiosyncracy?
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An unusual response to a drug
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A previously unknown use for a drug
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An unexpected response to a drug
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All of the above
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2 of the above
Correct Answer
A. 2 of the aboveExplanation
pg. 5Rate this question:
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- 9.
Which drug is used to treat bacterial conjunctivits?
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Metoprolol
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Impiramide
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Moxifloxacin
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Naloxone
Correct Answer
A. MoxifloxacinExplanation
aka Vigamox
metoprolol tx's HTN
naloxone is an opiate antagonist
impiramide is for bed wetting
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- 10.
Check ALL the effects associated with opiate withdrawal.
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Agitation
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Piloerection
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Diarrhea
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Runny nose
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Seizures
Correct Answer(s)
A. Agitation
A. Piloerection
A. Diarrhea
A. Runny noseExplanation
Rhinorrhea = runny nose
Other effects include: irritability, insomnia, drug-craving
(pg. 6)Rate this question:
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- 11.
Fluroscein is a:
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Diagnostic
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Prophylactic
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Treatment
Correct Answer
A. DiagnosticExplanation
Other examples of diagnostics: contrast media (x-ray), adenosine
pg. 4Rate this question:
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- 12.
What is another name for adverse drug effect (ADE)?
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Adverse drug reaction
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Alternative drug response
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Adverse drug response
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Alternative drug reaction
Correct Answer
A. Adverse drug reactionExplanation
aka ARDs
pg. 5Rate this question:
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- 13.
Pharmacotherapeutics are chemical entities/compounds that affect the actions of physiological processes, tissues, systems and/or organs
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True
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False
Correct Answer
A. FalseExplanation
This is the definition of a DRUG. A pharmacotherapeutics is the use of drugs for therapeutic purposes
Sub-categories: diagnostics, prophylatics, treatments
pg. 4Rate this question:
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- 14.
Most oral medications are absorbed where?
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Stomach
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Duodenum
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Ilium
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Depends on the drug
Correct Answer
A. DuodenumExplanation
Most oral medications are absorbed in the duodenum. The duodenum is the first part of the small intestine and is responsible for receiving partially digested food from the stomach. It has a large surface area and is lined with villi, which increase the absorption capacity. The duodenum also receives bile and pancreatic enzymes, which aid in the digestion and absorption of nutrients and medications. Therefore, the duodenum is the primary site of absorption for oral medications.Rate this question:
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- 15.
Withdrawal from CNS depressants is less life-threatening than withdrawal from opiates.
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True
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False
Correct Answer
A. FalseExplanation
Withdrawal from CNS depressants (e.g. alcohol) can lead to life-threatening seizures
Withdrawal from opiates (e.g. heroine) can lead to many unpleasant syndromes, but none that are life-threatening
pg. 6Rate this question:
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- 16.
Some antibiotics such as doxycycline or an oral fluroquinolone can interact with aluminum, magnesium, calcium or iron-containing compounds in a process called:
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Prevention of absorption
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Potentiation
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Additive effects
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Chelation
Correct Answer
A. ChelationExplanation
Chelation: aluminum, magnesium, calcium or iron-containing compounds can IRREVERSIBLY bind to some antibitoics thereby reducing the amount of drug absorbed
**this is an example of altered absorption
Hint: drugs that end in -cycline or -floxacine have issues with chelators
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- 17.
Dicloxacilin should be taken on a full stomach to protect the stomach and intestinal lining.
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True
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False
Correct Answer
A. FalseExplanation
Taking dicloxacillin on a full stomach will decrease its effectiveness by 60%
pg. 6Rate this question:
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- 18.
Amoxicillin and clavulanate is an example of what type of drug interaction?
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Additive effects
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Altered absorption
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Potentiation
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Synergism
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More than one of the above
Correct Answer
A. PotentiationExplanation
Potentiation: a drug which has no principal effect that enhances the effect of a second drog
0+1 = 2
The net result of this example is that a bacteria which may have demonstrated resistance to amoxicillin alone may still be sensitive when clavulanate is added to amxoicillin bc clavulanate protects the amoxicilin from being degraded by some of the beta-lactamase produced by some bacteria
(pg. 7)Rate this question:
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- 19.
The response elicitied by combined drugs is EQUAL to the combined response of the individual drugs is referred to as:
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Additive effects
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Synergism
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Potentiation
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Altered metabolism
Correct Answer
A. Additive effectsExplanation
1+1 = 2
ex) 2 drugs, each of which has CNS depressant effects will result in twice the CNS-depressant effects
pg. 7Rate this question:
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- 20.
What can occur if a drug that an indv is depedent on is abruptly discontinued?
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Tolerance
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Potentiation
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Withdrawal
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Chelation
Correct Answer
A. WithdrawalExplanation
pg. 6Rate this question:
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- 21.
What type of dependence can occur from opiate narcotic use?
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Physiological
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Psychological
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Drug withdrawal
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More than one of the above
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All of the above
Correct Answer
A. More than one of the aboveExplanation
Opiate narcotics can cause both physiological and psychological dependence. They can also cause drug withdrawal but this is not considered a TYPE of dependence.
pg. 6Rate this question:
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- 22.
Altered absorption occurs when a combo of 2 or more drugs _________ the absorption of one or more of the drugs being taken.
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Increases
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Inhibits
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Both of can occur depending on drug interaction
Correct Answer
A. InhibitsExplanation
pg. 6Rate this question:
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- 23.
Synergism refers to both the positive effect in one's treatment and the potential danger in administering a certain combination of drugs.
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True
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False
Correct Answer
A. FalseExplanation
The term synergism specifically refers to the intended clinical effects, and NOT the potential adverse effects
pg. 7Rate this question:
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- 24.
Choose which is false or unrelated to antagonism.
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Usually the antagonist has no inherent activity
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1+1 = 0
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Amoxicillin with clavulanate
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Naloxone and morphine
Correct Answer
A. Amoxicillin with clavulanateExplanation
Antagonism example: Naloxone and Morphine
-Net result is that naloxone will reverse the effects of morphine bc naloxone is an opiate antagonist with no other pharm activity. The CNS, cardiovascular and respiratory depressant effects of the drug will be reversed. Naxolone is often given in narcotic opiate overdose situations
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- 25.
Displacement of drug A from serum proteins by drug B may ______ the concentration of unbound drug A in the serum
Correct Answer
increasesExplanation
This type of interaction = competition for serum protein binding
Note: albumin is common carrier protein in serum
(pg. 8)Rate this question:
- 26.
Another name for amoxicillin with clavulanate is:
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Amoxil
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Amoxilnate
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Augmentin
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Amoxiclav
Correct Answer
A. AugmentinExplanation
pg. 7Rate this question:
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- 27.
The generic name for Viamox is ________.
Correct Answer
moxifloxacinExplanation
pg. 8Rate this question:
- 28.
Vancomycin and gentamicin to treat bacterial endocarditis is an example of what type of drug interaction?
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Additive effects
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Synergism
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Antagonism
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Potentiation
Correct Answer
A. SynergismExplanation
Synergism: 1+1 = 3
Combo of these meds is more effective in killing the bacteria causing the infection than the effect would be achieved by using either of the antibiotics alone
(pg. 7)Rate this question:
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- 29.
Altered excretion occurs when drugs act on the kidneys or other sites of elimination to ____________ excretion of specific drugs.
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Reduce
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Enhance
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Both can occur
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None of the above
Correct Answer
A. Both can occurExplanation
pg.8Rate this question:
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- 30.
The generic name for a drug is the propreitary name aka the brand name
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True
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False
Correct Answer
A. FalseExplanation
This is the definition for the trade name. (e.g. Bayer Asprin)
Generic name is the non-proprietary name or the common name by which the drug is known (e.g. asprin)
pg. 8Rate this question:
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Current Version
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Nov 28, 2023Quiz Edited by
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Dec 10, 2011Quiz Created by
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