Pharm Mt 1 Part I

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| Attempts: 87 | Questions: 27 | Updated: Nov 28, 2023
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1. In terms of tolerance, a drug has ____________ effectiveness over time with ___________ use.

Explanation

pg. 5

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About This Quiz
Pharm Mt 1 Part I - Quiz

Pharm MT 1 Part I is a quiz designed to assess knowledge in pharmacology, focusing on drug interactions, pharmacokinetics, and pharmacodynamics. It evaluates understanding of how drugs are absorbed, metabolized, and their effects, which is crucial for medical students and professionals.

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2. Which of the following does NOT correspond to pharmacodynamics?

Explanation

Pharmacodynamics--> think TIME
Pharmacokinetics --> think HOW the body deals with/processes a drug
Pharmacogenetics --> relationship btwn genetic factors and drug response
(pg. 5)

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3. Which drug is used to treat bacterial conjunctivits?

Explanation

aka Vigamox

metoprolol tx's HTN
naloxone is an opiate antagonist
impiramide is for bed wetting
(pg. 3-4)

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4. Fluroscein is a:

Explanation

Other examples of diagnostics: contrast media (x-ray), adenosine

pg. 4

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5. Some antibiotics such as doxycycline or an oral fluroquinolone can interact with aluminum, magnesium, calcium or iron-containing compounds in a process called:

Explanation

Chelation: aluminum, magnesium, calcium or iron-containing compounds can IRREVERSIBLY bind to some antibitoics thereby reducing the amount of drug absorbed
**this is an example of altered absorption

Hint: drugs that end in -cycline or -floxacine have issues with chelators
(pg. 6)

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6. The response elicitied by combined drugs is EQUAL to the combined response of the individual drugs is referred to as:

Explanation

1+1 = 2
ex) 2 drugs, each of which has CNS depressant effects will result in twice the CNS-depressant effects

pg. 7

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7. What can occur if a drug that an indv is depedent on is abruptly discontinued?

Explanation

pg. 6

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8. The generic name for Viamox is ________.

Explanation

pg. 8

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9. The generic name for a drug is the propreitary name aka the brand name

Explanation

This is the definition for the trade name. (e.g. Bayer Asprin)
Generic name is the non-proprietary name or the common name by which the drug is known (e.g. asprin)

pg. 8

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10. Dicloxacilin should be taken on a full stomach to protect the stomach and intestinal lining.

Explanation

Taking dicloxacillin on a full stomach will decrease its effectiveness by 60%

pg. 6

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11. Choose which is false or unrelated to antagonism.

Explanation

Antagonism example: Naloxone and Morphine
-Net result is that naloxone will reverse the effects of morphine bc naloxone is an opiate antagonist with no other pharm activity. The CNS, cardiovascular and respiratory depressant effects of the drug will be reversed. Naxolone is often given in narcotic opiate overdose situations
(pg. 7)

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12. Proparcaine is considered a type of treatment pharmacotherapeutic because it treats the adverse effects of tropicamide.

Explanation

Proparcaine is a prophylactic because it PREVENTS the adverse effects od dilating drops

Other prophylactics: flu shot
(pg.4)

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13. Withdrawal from CNS depressants is less life-threatening than withdrawal from opiates.

Explanation

Withdrawal from CNS depressants (e.g. alcohol) can lead to life-threatening seizures
Withdrawal from opiates (e.g. heroine) can lead to many unpleasant syndromes, but none that are life-threatening

pg. 6

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14. Most oral medications are absorbed where?

Explanation

Most oral medications are absorbed in the duodenum. The duodenum is the first part of the small intestine and is responsible for receiving partially digested food from the stomach. It has a large surface area and is lined with villi, which increase the absorption capacity. The duodenum also receives bile and pancreatic enzymes, which aid in the digestion and absorption of nutrients and medications. Therefore, the duodenum is the primary site of absorption for oral medications.

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15. Amoxicillin and clavulanate is an example of what type of drug interaction?

Explanation

Potentiation: a drug which has no principal effect that enhances the effect of a second drog
0+1 = 2

The net result of this example is that a bacteria which may have demonstrated resistance to amoxicillin alone may still be sensitive when clavulanate is added to amxoicillin bc clavulanate protects the amoxicilin from being degraded by some of the beta-lactamase produced by some bacteria
(pg. 7)

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16. Synergism refers to both the positive effect in one's treatment and the potential danger in administering a certain combination of drugs.

Explanation

The term synergism specifically refers to the intended clinical effects, and NOT the potential adverse effects

pg. 7

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17. Vancomycin and gentamicin to treat bacterial endocarditis is an example of what type of drug interaction?

Explanation

Synergism: 1+1 = 3
Combo of these meds is more effective in killing the bacteria causing the infection than the effect would be achieved by using either of the antibiotics alone
(pg. 7)

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18. Another name for amoxicillin with clavulanate is:

Explanation

pg. 7

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19. Check ALL processes that correspond to pharmacokinetics:

Explanation

pg.5

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20. Which of the following describes drug idiosyncracy?

Explanation

pg. 5

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21. What is another name for adverse drug effect (ADE)?

Explanation

aka ARDs

pg. 5

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22. Check ALL the effects associated with opiate withdrawal.

Explanation

Rhinorrhea = runny nose

Other effects include: irritability, insomnia, drug-craving
(pg. 6)

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23. What type of dependence can occur from opiate narcotic use?

Explanation

Opiate narcotics can cause both physiological and psychological dependence. They can also cause drug withdrawal but this is not considered a TYPE of dependence.

pg. 6

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24. Altered excretion occurs when drugs act on the kidneys or other sites of elimination to ____________ excretion of specific drugs.

Explanation

pg.8

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25. Altered absorption occurs when a combo of 2 or more drugs _________ the absorption of one or more of the drugs being taken.

Explanation

pg. 6

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26. Pharmacotherapeutics are chemical entities/compounds that affect the actions of physiological processes, tissues, systems and/or organs

Explanation

This is the definition of a DRUG. A pharmacotherapeutics is the use of drugs for therapeutic purposes

Sub-categories: diagnostics, prophylatics, treatments

pg. 4

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27. Displacement of drug A from serum proteins by drug B may ______ the concentration of unbound drug A in the serum

Explanation

This type of interaction = competition for serum protein binding

Note: albumin is common carrier protein in serum
(pg. 8)

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In terms of tolerance, a drug has ____________ effectiveness over time...
Which of the following does NOT correspond to pharmacodynamics?
Which drug is used to treat bacterial conjunctivits?
Fluroscein is a:
Some antibiotics such as doxycycline or an oral fluroquinolone can...
The response elicitied by combined drugs is EQUAL to the combined...
What can occur if a drug that an indv is depedent on is abruptly...
The generic name for Viamox is ________.
The generic name for a drug is the propreitary name aka the brand name
Dicloxacilin should be taken on a full stomach to protect the stomach...
Choose which is false or unrelated to antagonism.
Proparcaine is considered a type of treatment pharmacotherapeutic...
Withdrawal from CNS depressants is less life-threatening than...
Most oral medications are absorbed where?
Amoxicillin and clavulanate is an example of what type of drug...
Synergism refers to both the positive effect in one's treatment...
Vancomycin and gentamicin to treat bacterial endocarditis is an...
Another name for amoxicillin with clavulanate is:
Check ALL processes that correspond to pharmacokinetics:
Which of the following describes drug idiosyncracy?
What is another name for adverse drug effect (ADE)?
Check ALL the effects associated with opiate withdrawal.
What type of dependence can occur from opiate narcotic use?
Altered excretion occurs when drugs act on the kidneys or other sites...
Altered absorption occurs when a combo of 2 or more drugs _________...
Pharmacotherapeutics are chemical entities/compounds that affect the...
Displacement of drug A from serum proteins by drug B may ______ the...
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