Pharm Mt 1 Part I
Basic Pharmacology Defintions (Pgs. 4-8)
- 1.Describe how mannitol with cisplatinum leads to altered excretion.
- 2.Describe what is considered an 'empty stomach'
- 3.Descibe and give examples of the difference between physiological and psychological drug dependence.
- 4.Proparcaine is considered a type of treatment pharmacotherapeutic because it treats the adverse effects of tropicamide.
- A.
True
- B.
False
- 5.In terms of tolerance, a drug has ____________ effectiveness over time with ___________ use.
- 6.Check ALL processes that correspond to pharmacokinetics:
- A.
How drugs are absorbed in the body
- B.
Properties of drug effects
- C.
How drugs are biotransformed
- D.
How drugs are excreted in from the body
- E.
The relationship between genetic factors and drug response
- 7.Which of the following does NOT correspond to pharmacodynamics?
- A.
Time to onset of action
- B.
Duration of action
- C.
How a drug is metabolized in the body
- D.
Expected time for drug clearance
- 8.Which of the following describes drug idiosyncracy?
- A.
An unusual response to a drug
- B.
A previously unknown use for a drug
- C.
An unexpected response to a drug
- D.
All of the above
- E.
2 of the above
- 9.Which drug is used to treat bacterial conjunctivits?
- A.
Metoprolol
- B.
Impiramide
- C.
Moxifloxacin
- D.
Naloxone
- 10.Check ALL the effects associated with opiate withdrawal.
- A.
Agitation
- B.
Piloerection
- C.
Diarrhea
- D.
Runny nose
- E.
Seizures
- 11.Fluroscein is a:
- A.
Diagnostic
- B.
Prophylactic
- C.
Treatment
- 12.What is another name for adverse drug effect (ADE)?
- A.
Adverse drug reaction
- B.
Alternative drug response
- C.
Adverse drug response
- D.
Alternative drug reaction
- 13.Pharmacotherapeutics are chemical entities/compounds that affect the actions of physiological processes, tissues, systems and/or organs
- A.
True
- B.
False
- 14.Most oral medications are absorbed where?
- A.
Stomach
- B.
Duodenum
- C.
Ilium
- D.
Depends on the drug
- 15.Withdrawal from CNS depressants is less life-threatening than withdrawal from opiates.
- A.
True
- B.
False
- 16.Some antibiotics such as doxycycline or an oral fluroquinolone can interact with aluminum, magnesium, calcium or iron-containing compounds in a process called:
- A.
Prevention of absorption
- B.
Potentiation
- C.
Additive effects
- D.
Chelation
- 17.Dicloxacilin should be taken on a full stomach to protect the stomach and intestinal lining.
- A.
True
- B.
False
- 18.Amoxicillin and clavulanate is an example of what type of drug interaction?
- A.
Additive effects
- B.
Altered absorption
- C.
Potentiation
- D.
Synergism
- E.
More than one of the above
- 19.The response elicitied by combined drugs is EQUAL to the combined response of the individual drugs is referred to as:
- A.
Additive effects
- B.
Synergism
- C.
Potentiation
- D.
Altered metabolism
- 20.What can occur if a drug that an indv is depedent on is abruptly discontinued?
- A.
Tolerance
- B.
Potentiation
- C.
Withdrawal
- D.
Chelation
- 21.What type of dependence can occur from opiate narcotic use?
- A.
Physiological
- B.
Psychological
- C.
Drug withdrawal
- D.
More than one of the above
- E.
All of the above
- 22.Altered absorption occurs when a combo of 2 or more drugs _________ the absorption of one or more of the drugs being taken.
- A.
Increases
- B.
Inhibits
- C.
Both of can occur depending on drug interaction
- 23.Synergism refers to both the positive effect in one's treatment and the potential danger in administering a certain combination of drugs.
- A.
True
- B.
False
- 24.Choose which is false or unrelated to antagonism.
- A.
Usually the antagonist has no inherent activity
- B.
1+1 = 0
- C.
Amoxicillin with clavulanate
- D.
Naloxone and morphine
- 25.Displacement of drug A from serum proteins by drug B may ______ the concentration of unbound drug A in the serum
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