2012 Pharm II - Quiz 2

83 Questions | Total Attempts: 171

SettingsSettingsSettings
Please wait...
Drug Quizzes & Trivia

A quiz reviewing the material for Quiz 3. Sympathomimetics, Calcium channel blockers, Antiarrhythmics


Questions and Answers
  • 1. 
    What is the postsynaptic neurotransmitter of the parasympathetic nervous system?
    • A. 

      Acetylcholine

    • B. 

      Norepinephrine

    • C. 

      Epinephrine

    • D. 

      Tyrosine

  • 2. 
    What is the postsynaptic neurotransmitter of the sympathetic nervous system?
    • A. 

      Acetylcholine

    • B. 

      Norepinephrine

    • C. 

      Epinephrine

    • D. 

      Tyrosine

  • 3. 
    Which of the following is release from the adrenal gland in times of stress and acts on alpha and beta receptors?
    • A. 

      Dopamine

    • B. 

      Norepinephrine

    • C. 

      Epinephrine

    • D. 

      Acetylcholine

  • 4. 
    Where is norepinephrine synthesized?
    • A. 

      Post-synaptic neurons

    • B. 

      Pineal Body

    • C. 

      Posterior Lobe of Pituitary

    • D. 

      Synaptic Vessicles

  • 5. 
    When Tyrosine is hydroxylated it becomes what?
    • A. 

      Dopa

    • B. 

      Phenylalanine

    • C. 

      Norepinephrine

    • D. 

      Epinephrine

  • 6. 
    What enzyme acts on Dopamine to turn it into Norepinephrine?
    • A. 

      N-methyltransferase

    • B. 

      Dopamine B-Hydroxylase

    • C. 

      DOPA decarboxylase

    • D. 

      Dopamine does not directly turn into norepi… you’re missing a step.

  • 7. 
    Which of the following is not one of the 3 mechanisms for termination of norepinephrine?
    • A. 

      Re-uptake

    • B. 

      Diffusion from receptor sites

    • C. 

      Irreversible protein binding

    • D. 

      Enzyme degredation

  • 8. 
    When a neurotransmitter binds to a postsynaptic receptor it is likely to likely cause which of the following?
    • A. 

      Opening of an ion channel

    • B. 

      Activation of a second messenger such as cAMP or inositol phosphate

    • C. 

      Depolarization

    • D. 

      All of above.

  • 9. 
    After the breakdown of epinephrine by MAO and COMT, what product is excreted in the urine?
    • A. 

      Vanillymandelic Acid

    • B. 

      3,7-dicarboxyvandelic acid

    • C. 

      Nelson-Mandelic Acid

    • D. 

      4,6-Pheocomtic acid

  • 10. 
    Norepinephrine is synthesized from ______ which is hydroxylated to form Dopa.
    • A. 

      Dopamine

    • B. 

      Tyrosine

    • C. 

      COMT

    • D. 

      Phenylalanine

  • 11. 
    Where does dopa-b hydroxylase act upon dopamine to turn it into norepinephrine?
    • A. 

      Mitochondria

    • B. 

      Synaptic cleft

    • C. 

      Synaptic Vessicles

    • D. 

      Storage Vessicles

  • 12. 
    Which of the following is not a cardiac effect of alpa 1 receptor activation?
    • A. 

      Decrease SVR

    • B. 

      Vasoconstriction

    • C. 

      Increase LV afterload

    • D. 

      Increase arterial BP

  • 13. 
    Which of the following is a pre-synaptic receptor?
    • A. 

      Alpha 1

    • B. 

      Alpha 2

    • C. 

      Beta 1

    • D. 

      Beta 2

  • 14. 
    Activation of Alpha 2 receptors inhibits ______ activity.
    • A. 

      Dopa-b hydroxylase

    • B. 

      Tyrosine

    • C. 

      Adenylate cyclase

    • D. 

      COMT

  • 15. 
    Stimulation of Beta 1 receptors is likely to have all of the following effects except …
    • A. 

      Increase Contractility

    • B. 

      Increase HR

    • C. 

      Increase CO

    • D. 

      Decreased SVR

  • 16. 
    Beta 2 agonism may result in which of the following electrolyte imbalances?
    • A. 

      Hypokalemia

    • B. 

      Hypochloremia

    • C. 

      Hyponatremia

    • D. 

      None of above

  • 17. 
    Which of the following is not a direct sympathomimetic?
    • A. 

      Phenylephrine

    • B. 

      Amphetamine

    • C. 

      Isoproterenol

    • D. 

      Dobutamine

  • 18. 
    Which of the following is not a direct acting catecholamine?               
    • A. 

      Epinephrine

    • B. 

      Dobutamine

    • C. 

      Phenylephrine

    • D. 

      Isoproterenol

  • 19. 
    What is the most potent activator of alpha adrenergic receptors?
    • A. 

      Norepinephrine

    • B. 

      Ephedrine

    • C. 

      Phenylephrine

    • D. 

      Epinephrine

  • 20. 
    Which of the following would not be an effect of epinephrine?               
    • A. 

      Increased renal blood flow

    • B. 

      Increase rate of phase IV depolarization

    • C. 

      Bronchodilation

    • D. 

      Increase cerebral perfusion pressure

  • 21. 
    What is the appropriate shock and allergic reaction dose of epinephrine?
    • A. 

      1:1000 solution .1-.5 ml SQ/IM

    • B. 

      0.05 -1mg IV

    • C. 

      2-20 ug/min

    • D. 

      Racemic inhalation 0.5 ml of 2.25% solution

  • 22. 
    A 1: 10,000 mix of epinephrine contains how many micrograms of epinephrine per ml?               
    • A. 

      10

    • B. 

      5

    • C. 

      100

    • D. 

      20

  • 23. 
    Epinephrine should be used cautiously in patients with what condition?
    • A. 

      Dysrhythmias

    • B. 

      Renal Failure

    • C. 

      COPD

    • D. 

      Hypertensive ischemic heart disease

  • 24. 
    Norepinephrine exerts its greatest action on which receptors?
    • A. 

      Alpha

    • B. 

      Beta 1

    • C. 

      Beta 2

    • D. 

      All are equal

  • 25. 
    Which of the following is not an effect of norepinephrine?               
    • A. 

      Increase myocardial O2 demand

    • B. 

      Increase CO

    • C. 

      Bradycardia

    • D. 

      Increase Afterload