Lecture 8
True
False
Synthesis within the neuron
Presence within the synaptic terminal and release in amounts sufficient to initiate an effect on the postsynaptic cell
When applied exogenously, it has a seperate effect from when it is applied endogenously
A seperate mechanism exists for removing it from the synaptic cleft
Noradrenaline
Adrenaline
Acetylcholine
Dopamine
Serotonin
Histamine
5-HT
Glutamate
GABA (gamma-aminobutyric acid)
Glycine
Aspirin
Posaconazole
Sildenafil
Simvastin
True
False
True
False
True
False
The pre-ganglionic fibres of the sympathetic nervous system
The pre-ganglionic fibres of the parasympathetic nervous system
The post-ganglionic fibres of the sympathetic nervous system
The post-ganglionic fibres of the parasympathetic nervous system
Acetylcholine synthase
Choline kinase
Acetylcholine estertransferase
Choline acetyltransferase
Passive transport through the vesicle membrane (facillitated diffusion)
Cotransported against its concentration gradient using a proton pump to generate energy and an antiport coupled channel (ACh-H+) to tranfer it into the cell
Utilization of energy from the hydrolysis of ATP to transport it against its concentration gradient (active transport)
Cotransported against its concentration gradient using a proton pump to generate energy and a symport coupled channel (ACh-H+) to tranfer it into the cell
Through a specific Ch-Na+ symport cotransporter
Through a specific Ch-Na+ antiport cotransporter
Through a specific Ch-K+ symport cotransporter
Through a specific Ch-K+ antiport cotransporter
Are G-protein coupled receptors (ionotropic receptors)
Are ligand-gated ion channels (ionotropic receptors)
Are G-protein coupled receptors (metabotropic receptors)
Are ligand-gated ion channels (metabotropic receptors)
Are G-protein coupled receptors (ionotropic receptors)
Are ligand-gated ion channels (ionotropic receptors)
Are G-protein coupled receptors (metabotropic receptors)
Are ligand-gated ion channels (metabotropic receptors)
Tyrosine -> Dopamine -> DOPA -> Noradrenaline -> Adrenaline
Tyrosine -> DOPA -> Noradrenaline -> Dopamine -> Adrenaline
Tyrosine -> Dopamine -> Noradrenaline -> DOPA -> Adrenaline
Tyrosine -> DOPA -> Dopamine -> Noradrenaline -> Adrenaline
Tyrosine hydroxylase
Phenylethanolamine N-methyl transferase
Dopamine beta-hydroxylase
DOPA decarboxylase
Tyrosine hydroxylase
Phenylethanolamine N-methyl transferase
Dopamine beta-hydroxylase
DOPA decarboxylase
Tyrosine hydroxylase
Phenylethanolamine N-methyl transferase
Dopamine beta-hydroxylase
DOPA decarboxylase
Tyrosine hydroxylase
Phenylethanolamine N-methyl transferase
Dopamine beta-hydroxylase
DOPA decarboxylase
Noradrenaline is recycled back into the synaptic terminal (NET)
Noradenaline is taken up by adjacent cells (VMAT)
Is the major inhbitory neurotransmitter of the CNS
Is an inhibitory neurotransmitter of the CNS
Is the major excitatory neurotransmitter of the CNS
Is an excitatory neurotransmitter of the CNS
Is the major inhbitory neurotransmitter of the CNS
Is an inhibitory neurotransmitter of the CNS
Is the major excitatory neurotransmitter of the CNS
Is an excitatory neurotransmitter of the CNS
Is the major inhbitory neurotransmitter of the CNS
Is an inhibitory neurotransmitter of the CNS
Is the major excitatory neurotransmitter of the CNS
Is an excitatory neurotransmitter of the CNS
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