Explore the Peripheral Nervous System and synaptic pharmacology through a focus on neurotransmitters. This quiz assesses knowledge on neurotransmitter criteria, types, and specific pharmacological interactions, enhancing understanding of neurochemical processes and their pharmacological modulation.
True
False
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True
False
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Tyrosine hydroxylase
Phenylethanolamine N-methyl transferase
Dopamine beta-hydroxylase
DOPA decarboxylase
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Noradrenaline is recycled back into the synaptic terminal (NET)
Noradenaline is taken up by adjacent cells (VMAT)
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Is the major inhbitory neurotransmitter of the CNS
Is an inhibitory neurotransmitter of the CNS
Is the major excitatory neurotransmitter of the CNS
Is an excitatory neurotransmitter of the CNS
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5-HT
Glutamate
GABA (gamma-aminobutyric acid)
Glycine
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The pre-ganglionic fibres of the sympathetic nervous system
The pre-ganglionic fibres of the parasympathetic nervous system
The post-ganglionic fibres of the sympathetic nervous system
The post-ganglionic fibres of the parasympathetic nervous system
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Tyrosine hydroxylase
Phenylethanolamine N-methyl transferase
Dopamine beta-hydroxylase
DOPA decarboxylase
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Tyrosine hydroxylase
Phenylethanolamine N-methyl transferase
Dopamine beta-hydroxylase
DOPA decarboxylase
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Are G-protein coupled receptors (ionotropic receptors)
Are ligand-gated ion channels (ionotropic receptors)
Are G-protein coupled receptors (metabotropic receptors)
Are ligand-gated ion channels (metabotropic receptors)
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Tyrosine -> Dopamine -> DOPA -> Noradrenaline -> Adrenaline
Tyrosine -> DOPA -> Noradrenaline -> Dopamine -> Adrenaline
Tyrosine -> Dopamine -> Noradrenaline -> DOPA -> Adrenaline
Tyrosine -> DOPA -> Dopamine -> Noradrenaline -> Adrenaline
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True
False
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Synthesis within the neuron
Presence within the synaptic terminal and release in amounts sufficient to initiate an effect on the postsynaptic cell
When applied exogenously, it has a seperate effect from when it is applied endogenously
A seperate mechanism exists for removing it from the synaptic cleft
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True
False
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Acetylcholine synthase
Choline kinase
Acetylcholine estertransferase
Choline acetyltransferase
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Are G-protein coupled receptors (ionotropic receptors)
Are ligand-gated ion channels (ionotropic receptors)
Are G-protein coupled receptors (metabotropic receptors)
Are ligand-gated ion channels (metabotropic receptors)
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Is the major inhbitory neurotransmitter of the CNS
Is an inhibitory neurotransmitter of the CNS
Is the major excitatory neurotransmitter of the CNS
Is an excitatory neurotransmitter of the CNS
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Is the major inhbitory neurotransmitter of the CNS
Is an inhibitory neurotransmitter of the CNS
Is the major excitatory neurotransmitter of the CNS
Is an excitatory neurotransmitter of the CNS
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Noradrenaline
Adrenaline
Acetylcholine
Dopamine
Serotonin
Histamine
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Aspirin
Posaconazole
Sildenafil
Simvastin
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Through a specific Ch-Na+ symport cotransporter
Through a specific Ch-Na+ antiport cotransporter
Through a specific Ch-K+ symport cotransporter
Through a specific Ch-K+ antiport cotransporter
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Passive transport through the vesicle membrane (facillitated diffusion)
Cotransported against its concentration gradient using a proton pump to generate energy and an antiport coupled channel (ACh-H+) to tranfer it into the cell
Utilization of energy from the hydrolysis of ATP to transport it against its concentration gradient (active transport)
Cotransported against its concentration gradient using a proton pump to generate energy and a symport coupled channel (ACh-H+) to tranfer it into the cell
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