Unit 4 Chee 370

37 Questions | By Sboo | Updated: Mar 20, 2022 | Attempts: 190

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1.

The mutation rate of DNA replication is about 1 in 10^4 nucleotides
- A.
  
  True
- B.
  
  False
2.

Okazaki fragments are about ________ nucleotides long.
- A.
  
  1000 to 2000
- B.
  
  100 to 200
- C.
  
  10 to 200
- D.
  
  10 to 20
3.

What is not a way that RNA polymerase is different from DNA polymerase?
- A.
  
  RNA polymerases don't need primer to start a chain
- B.
  
  RNA polymerases don't have a proofreading mechanism
- C.
  
  RNA polymerase links ribonucleotides
- D.
  
  RNA is not structurally similar, except for the Mg2+ ion at the catalytic site
4.

The sigma factor seeks the _______ region on the DNA molecule to tightly bind the polymerase
5.

Like DNA helicase, RNA polymerase requires the energy of ATP hydrolysis to open the helix
- A.
  
  True
- B.
  
  False
6.

During transcription, bacterial RNA polymerase will continue RNA chain elongation down the strand until it encounter the signal of the _______.
7.

The bacterial transcription termination sequence is a long string of ________ pairs, and then an inverted repeat sequence that forms a ________ structure when transcribed into RNA.
- A.
  
  C-G ; hairpin
- B.
  
  C-G ; theta
- C.
  
  A-T ; hairpin
- D.
  
  A-T ; theta
8.

A _________ sequence is derived by comparing many sequences with the same basic function and finding the most common nucleotide found at each position
9.

TRNAs are about _____ nucleotides long
- A.
  
  10
- B.
  
  20
- C.
  
  40
- D.
  
  80
10.

In tRNA, the amino acid binding site is located at the:
- A.
  
  3' end
- B.
  
  5' end
11.

Some amino acids may have more than one matching tRNA
- A.
  
  True
- B.
  
  False
12.

TRNAs are covalently modified right after they exit the nucleus
- A.
  
  True
- B.
  
  False
13.

Eukaryotic tRNAs are synthesized by:
- A.
  
  RNA Polymerase I
- B.
  
  RNA Polymerase II
- C.
  
  RNA Polymerase III
- D.
  
  DNA Polymerase
14.

Amino acids are coupled to their tRNA molecules by:
- A.
  
  Aminoacyl-tRNA transferase
- B.
  
  Aminoacyl-tRNA synthetase
- C.
  
  Aminoacyl-tRNA nuclease
- D.
  
  They do not need enzymatic aid to couple
15.

A protein is synthesized from its _____ to ____ terminal end
- A.
  
  N ; C
- B.
  
  C ; N
16.

Protein synthesis has about 1 mistake in _______ amino acids
- A.
  
  5,000
- B.
  
  10,000
- C.
  
  100,000
- D.
  
  10^9
17.

Protein synthesis occurs in the _______
18.

Check the things that apply to EUKARYOTIC RNA polymerase
- A.
  
  There is only one
- B.
  
  It needs many proteins called general transcription factors for initiation
- C.
  
  There are three, all are used for transcribing genes/proteins
- D.
  
  It needs one protein (sigma factor) for initiation
- E.
  
  There are three, only one is generally used for transcribing genes/proteins
- F.
  
  Transcription initiation has to deal with packing DNA into nucleosome and chromatin structure
19.

The TATA box is a ________ sequence that is recognized by the _________ factor and is located 25 nucleotides ______ from the transcription start site.
- A.
  
  Promoter ; sigma ; upstream
- B.
  
  Promoter ; TFIID ; upstream
- C.
  
  Promoter ; TFIIB ; downstream
- D.
  
  Terminating ; TFIIB ; upstream
20.

The start codon for translation of mRNA is ___
21.

The tRNA that carries the start codon is called ________
22.

Prokaryotic mRNA uses Shine Dalgarno sequence to initiation translation
- A.
  
  True
- B.
  
  False
23.

Which are possible stop codons:
- A.
  
  UAA
- B.
  
  GUA
- C.
  
  UAG
- D.
  
  UGA
24.

When polymerase start without a free 3'OH end it is called __ _____, and is not very accurate.
25.

The Pribnow box and the 35 sequence are regions in prokaryotic promoters
- A.
  
  True
- B.
  
  False