Nervous System Pathology 2

10 Questions | Total Attempts: 73

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Nervous System Pathology 2


Questions and Answers
  • 1. 
    Which of the following statements about Multiple sclerosis are true? (Select 2)
    • A. 

      Is autoimmune with T-Cell involvement

    • B. 

      CNS axons are destroyed

    • C. 

      A symptom is a shock like sensation when the patient flexes their neck (Lhermitte's sign)

    • D. 

      Grey matter in the CNS is selectively destroyed, but not in the PNS.

  • 2. 
    A patient presents with paralysis in her feet and is beginning to notice weakness in her hands. She has diminished reflexes in her lower limbs as well. You do a thorough case history and find she was ill 3 weeks ago with a viral infection. What should you rule out first?
    • A. 

      Multiple sclerosis

    • B. 

      Parkinson disease

    • C. 

      Huntington disease

    • D. 

      Guillain-Barre syndrome

  • 3. 
    Alzheimer's disease is irreversible.
    • A. 

      True

    • B. 

      False

  • 4. 
    Alzheimer's disease (Select 2)
    • A. 

      Is associated with destruction of dopaminergic neurons

    • B. 

      Shows Beta-amyloid plaques, Lewis bodies, and neurofibrillary tangles

    • C. 

      Will initially show loss of long term memory

    • D. 

      Can be treated by blocking the action of Cholinesterase

    • E. 

      Can be treated by activating the NMDA receptor

  • 5. 
    Which of the following is NOT true regarding Parkinson's disease?
    • A. 

      It is a hypokinetic disorder

    • B. 

      Dopamine deficiency is believed to be the main cause

    • C. 

      Lewis bodies are often present in the diagnosis

    • D. 

      A decrease in acetylcholine is present

    • E. 

      A COMT agonist would be a poor treatment option

  • 6. 
    In Duchenne Muscular Dystrophy (Select 2)
    • A. 

      There is an absence of dystrophin

    • B. 

      The defective gene is the PIG-A gene on the X chromosome

    • C. 

      There is a decreased production of dystrophin

    • D. 

      It is caused by an increase in acetylcholine receptor destruction at the NMJ

  • 7. 
    Chloroquine use is associated with which type of disease?
    • A. 

      Myasthenia Gravis

    • B. 

      Parkinson's disease

    • C. 

      Muscular dystrophy

    • D. 

      CIPD

  • 8. 
    A Tensilon test is used to help in the diagnosis of which disease and why? (Select 2)
    • A. 

      Myasthenia Gravis

    • B. 

      Duchenne Muscular Dystrophy

    • C. 

      Guillan-Barre Syndrome

    • D. 

      It will temporarily increase the amount of acetylcholine available and show temporary decreased clinical symptoms

    • E. 

      It will temporarily activate the AchE enzyme and temporarily decrease the clinical symptoms of the disease

  • 9. 
    The most common primary brain tumor of adults is
    • A. 

      Atrocytoma

    • B. 

      Meningioma

    • C. 

      Pituitary adenoma

    • D. 

      Craniopharyngioma