Molecular Genetics Review
(165).jpg "Molecular Genetics Review")
There are so many ways in which we can put our knowledge of genetics to good use. The most effective way, for example, is that we can look at our heredity to see if our parents or someone else in generations further up suffering from a disease makes us more likely to develop it ourselves! It’s an amazing scientific innovation, and today we’ll be seeing how much you know about molecular genetics!
- 1.Select the CORRECT statement about DNA and RNA:
- A.
DNA is a single strand; RNA is a double strand.
- B.
DNA contains thymine; so does RNA.
- C.
DNA and RNA are both found in the cytosol.
- D.
Thymine is absent in RNA, but is present in DNA.
- E.
RNA is the main component in ribosomes, tRNA and mRNA.
- 2.The sequence of DNA 3'-ACCGTTACC-5' would be transcribed as follows:
- A.
TGGCAATCC
- B.
UGGCAAUCC
- C.
TCCUAAUGG
- D.
UGGCAAUGG
- 3.5' and 3' refer to:
- A.
Numbered carbon atoms in any molecule with at least 5 carbons.
- B.
The direction of the DNA strand.
- C.
Bond formation between adjacent nucleotides in the DNA molecule.
- D.
The carbon atoms which have a phosphate and a carboxyl group attached respectively.
- 4.Which enzyme is incorrectly paired with its function?
- A.
Helicase - the DNA molecule "unzipping".
- B.
Gyrase - relieves tension in the unzipping DNA strand
- C.
DNA polymerase III - adds DNA nucleosides to a DNA template
- D.
RNA polymerase - adds RNA nucleosides to a growing rRNA strand
- 5.The leading strand and the lagging strand have roles in:
- A.
Transcription
- B.
Translation
- C.
DNA replication
- D.
Both A and B
- E.
All of a, b and c
- 6.The molecule(s) that does not act to make a new DNA molecule is/are:
- A.
RNA polymerase
- B.
Helicase
- C.
Gyrase
- D.
SSBs
- E.
Primase
- F.
All of a, b, c and d are involved in DNA replication
- 7.Using the enclosed table of messenger RNA codons, select the NUMBER of CORRECT statements about the following sequence of RNA bases: AUG AAG AAA GGU UGA CAC UCU (i) It is a normal polypeptide since it starts off with a methionine. (ii) The polypeptide is six amino acids long. (iii) The sequence of amino acids could be altered by a point mutation in the third codon, AAA, to AAG. (iv) The sequence of amino acids shown above would constitute a large polypeptide. (v) The polypeptide includes a molecule of lysine. The number of correct statements above is:
- A.
1
- B.
2
- C.
3
- D.
4
- E.
You have to look this up and figure out what the answer is!
- 8.All the following are mutagens (can cause mutations), EXCEPT:
- A.
X-rays
- B.
Gamma rays
- C.
Dideoxynucleotides
- D.
UV rays
- E.
Chemicals that mimic nucleotide bases
- 9.Select the INCORRECT statement about a eukaryotic DNA molecule:
- A.
It has an anti-parallel arrangement
- B.
It replicates in a semi-conservative manner.
- C.
The new DNA molecule formed after replication contains 50% of the original template.
- D.
It can consist of several thousand nucleotides.
- E.
It is found associated with a protein, haptitone.
- 10.During translation, a transfer RNA (tRNA) molecule is associated with:
- A.
An amino acid molecule, a DNA molecule, and a ribosome.
- B.
An amino acid, a messenger RNA molecule and a ribosome.
- C.
A nucleolus, mRNA and DNA
- D.
RRNA molecule, DNA molecule, and a phosphate
- E.
An amino acid, rRNA and DNA
- 11.For which processes is RFLP required?
- A.
DNA fingerprinting
- B.
PCR
- C.
Sanger dideoxy sequencing
- D.
Both a and c
- 12.Which biotechnology method most closely resembles natural DNA replication?
- A.
RFLP
- B.
DNA fingerprinting
- C.
Cloning
- D.
PCR
- E.
Sanger Dideoxy sequencing
- 13.Post transcriptional modificiations DO NOT include:
- A.
Adding a 5' methyl cap
- B.
Cutting out exons
- C.
Adding a poly adenylated tail to the 5' end
- D.
Cutting out introns
- E.
Adding a poly adenylated tail to the 3' end
- F.
More than one of these is a correct answer
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