Bio1334 Genetics - Molecular Genetics - DNA And Chromosomes (Lecture One)
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Quiz on content from Lecture One of Genetics module.
- 1.Name the Scientist that isolated nuclein (now nucleic acid) from human pus.
- A.
Friedrich Miescher
- B.
Rosalind Franklin
- C.
Alfred Hershey
- D.
Francis Crick
- 2.Which of the following did Rosalind Franklin conclude about the structure of DNA?(Select more than one answer)
- A.
The structure is double-helical
- B.
Phosphate groups lie on the outside of the molecule
- C.
The helix is 20 nanometers in diameter
- D.
DNA has directionality (5' and 3' ends)
- E.
DNA has four nitrogenous bases
- 3.Name the sugar in DNA.
- 4.Sugar + base + phosphate(s) = ?
- 5.Sugar + base = ?
- 6.Deoxyribose + adenine = ?
- 7.Deoxyribose + guanine = ?
- 8.Deoxyribose + cytosine = ?
- 9.Deoxyribose + thymine = ?
- 10.5' and 3' ends give DNA molecules directionality.True or False: DNA is synthesised in the 3'-to-5' direction.
- A.
True
- B.
False
- 11.True or false: In a DNA double-helix, the 5' end of one strand is opposite the 3' end of another strand.
- A.
True
- B.
False
- 12.Which of the following statements is true?
- A.
Two hydrogen bonds form between adenine and thymine, whereas three form between cytosine and guanine. Bonding is therefore stronger between C and G.
- B.
Two hydrogen bonds form between cytosine and guanine, whereas three form between adenine and thymine. Bonding is therefore stronger between A and T.
- C.
Two hydrogen bonds form between both adenine and thymine, and cytosine and guanine. Bonds between the two bases are equally as strong.
- D.
Three hydrogen bonds form between both adenine and thymine, and cytosine and guanine. Bonds between the two bases are equally as strong.
- 13.Which of the following statements is correct?
- A.
Adenine and thymine are purines. Cytosine and guanine are pyrimidines.
- B.
Adenine and guanine are purines. Cytosine and thymine are pyrimidines.
- C.
Guanine and cytosine are purines. Adenine and thymine are pyrimidines.
- D.
Cytosine and thymine are purines. Adenine and guanine are pyrimidines.
- 14.Which of the following images shows a right-handed double helix?
- A.
This one!
- B.
This one!
- C.
Option 3
- D.
Option 4
- 15.True or false: DNA is a right-handed double helix.
- A.
True
- B.
False
- 16.Fill in the blank:DNA is a _______ code, because it has four possible bases.
- 17.Match the following to its complementary strand: 5′-TGGTCGGAATT-3′
- A.
5′-AATTCCGACCA-3′
- B.
5′-ACCAGCCTTAA-3′
- C.
5′-TGGTCGGAATT-3′
- D.
5′-TTAAGGCTGGT-3′
- 18.Fill in the blank:A ______ is the complete set of genes for an organism.
- 19.How many base pairs can be found in every human cell?
- A.
6 x 10^9 base pairs
- B.
6 x 10^6 base pairs
- C.
6 x 10^12 base pairs
- D.
6 x 10^3 base pairs
- 20.What is the name given to the protein that DNA wraps around in order to 'package' the DNA?
- 21.Which of the following statements is correct?
- A.
DNA wraps twice around 8 histone proteins to form nucleosomes.
- B.
DNA wraps once around 8 histone proteins to form nucleosomes.
- C.
DNA wraps twice around 8 histone proteins to form nucleotides.
- D.
DNA wraps once around 8 histone proteins to form nucleotides.
- 22.When DNA wraps around the histone protein, what is the name of the structure formed?
- 23.
- A.
True
- B.
False
- 24.Fill in the blank:Histone protein H1 is known as a ______ protein.
- 25.Fill in the blank:Histone H1 brings the nucleosomes together to form a _________________.
- 26.Fill in the blank:After chromatin fibre is formed by the Histone H1 protein, chromatin is further condensed by ______________.
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