M&R Review By : KMSA-MED

2.

[x] If A is suddenly withdrawn after chronic use and the patient has inverse symptoms like tachycardia, hypertension...You think A is....bcz ....

Metaprolol,up regulation
Salbutamol,up regulation
Dobutamine,down regulation
Yohimbine,up regulation

Correct Answer

A. Metaprolol,up regulation

3.

These drugs are used treatment of glaucoma except

Dobutamine
Timolol
Pilocarpine
Apraclonidine

Correct Answer

A. Dobutamine

4.

Procaine mechanism of action is

Blocking Na channel
Blocking Na pump
Blocking Ca channel
Activating k channel

Correct Answer

A. Blocking Na channel

5.

Na Ca exchanger consider a :-

Secondary active antiport
Secondary active symport
Primary active
Ligand gated channel

Correct Answer

A. Secondary active antiport

6.

Capacitance of large unmyelinated fiber is :-

Higher than that of large myelinated fibers
Lower than that of myelinated fiber
Equal to capacitance of myelinated fibers
None of above

Correct Answer

A. Higher than that of large myelinated fibers

7.

One of the followings is not a neurotransmitter

DAG
Glycine
Dopamine
Acetylcholine

Correct Answer

A. DAG

8.

The inverse agonist has Emax.............while antagonist Emax is..............

0,
>0,>0.

Correct Answer

A.

9.

C sensory fibers have a characteristics of :-

Low resistance and high capacitance
High capacitance and high resistance
High resistance and low capacitance
Low resistance and low capacitance

Correct Answer

A. Low resistance and high capacitance

10.

Years old patient presented with fever and rectal temperature of 38.3 what would you predict about membrane cholesterol role in that patient :-

Decrease fluidity
Increase fluidity
Increase permeability
Both second and third choice

Correct Answer

A. Decrease fluidity

11.

Apotransferrin dissociate from its receptors at

Neutral PH
Low PH
High Fe level
Low Fe level

Correct Answer

A. Neutral pH

12.

Increase membrane Cl permeability results in :-

Difficulty to initiate a stimulatory action potential
Increase cell excitability
Block K channel
Decrease Na pumping activity

Correct Answer

A. Difficulty to initiate a stimulatory action potential

Explanation

Feedback : increase Cl permeability mean the membrane exposed to an inhibitory neurotransmitter

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13.

V2 vasopressin receptors, activated by ------- . And located in------

ADH , kidney
ADH , blood vessels
Angiotensin 2 , kidney
Angiotensin 2 , blood vessels

Correct Answer

A. ADH , kidney

14.

B blocker help hypertensive by several mechanisms except

Vasodilation
Decrease SV
-ve chronotropic effect
Inhibition of renin system

Correct Answer

A. Vasodilation

15.

Asthmatic pt due to allergy(allergic asthma) You prefer to give him

Beclomethasone
Diphenhydramine
Antihistamine
Cromoglycate

Correct Answer

A. Beclomethasone

16.

Drug's side effects tend to become less intense with time , even though drug administration is continued due to :-

Physiological adaptation
Receptor conformational changes
Numerical down regulation
Exhaustion of mediators

Correct Answer

A. Physiological adaptation

17.

An case with MI due occlusion of one of coronary arteries due to thrombus has given warfarin, before coming to A&E he took allopurinol as treatment of gout arthritis and erythromycin as treatment of Tonsillitis drug interaction of drugs may lead to : .

Bleeding
Another thrombus
Angina
HyperAcute

Correct Answer

A. Bleeding

Explanation

the plot of Loge Drug level against time is a straight line called..
While the plot of Drug level against time is a straight line called..
Linear kinetic (First order),non linear (zero order)
Non linear (Zero order),linear(first order)

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18.

Prolonged usage of loop diuretic may cause :-

Hypokalemia
Hyperkalemia
Hypocalcemia
Hypercalcemia

Correct Answer

A. Hypokalemia

19.

These substances help in lowering of HT except

Methoxamine
Clonidine
Guanethedine
Insecticide organophosphorous

Correct Answer

A. Methoxamine

20.

[x] This drug is cautious to give to a diabetic patient

Propanolol
Dopamine
Prazosin
Clonidine

Correct Answer

A. Propanolol

21.

[x] 43 years old hypertensive man suffer from enlarged prostate,the most suitable drug to give is(most suitable)

Prazosin
Dobutamine
Salbutamol
Tamsulusin

Correct Answer

A. Prazosin

Explanation

Answer is prazosin bcz its non selective alpha 1 antagonist so treats hypertension and prostate enlargement
If he is not hypertensive we will prefer to give tamsulusin which is an α 1 antagonist that is more selective to the α 1 receptor subtype (α 1A ) present in the prostate and less selective to the α 1 receptor subtype (α 1B ) present in the blood vessels.so we won’t have hypotension as side effect,in contrast the prazosin

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M&r Review By : Kmsa-med

Glycine mechanism of action is :-

Quiz Preview

[x] If A is suddenly withdrawn after chronic use and the patient has inverse symptoms like tachycardia, hypertension...You think A is....bcz ....

These drugs are used treatment of glaucoma except

Procaine mechanism of action is

Na Ca exchanger consider a :-

Capacitance of large unmyelinated fiber is :-

One of the followings is not a neurotransmitter

The inverse agonist has Emax.............while antagonist Emax is..............

C sensory fibers have a characteristics of :-

Years old patient presented with fever and rectal temperature of 38.3 what would you predict about membrane cholesterol role in that patient :-

Apotransferrin dissociate from its receptors at

Increase membrane Cl permeability results in :-

V2 vasopressin receptors, activated by ------- . And located in------

B blocker help hypertensive by several mechanisms except

Asthmatic pt due to allergy(allergic asthma) You prefer to give him

Drug's side effects tend to become less intense with time , even though drug administration is continued due to :-

An case with MI due occlusion of one of coronary arteries due to thrombus has given warfarin, before coming to A&E he took allopurinol as treatment of gout arthritis and erythromycin as treatment of Tonsillitis drug interaction of drugs may lead to : .

Prolonged usage of loop diuretic may cause :-

These substances help in lowering of HT except

[x] This drug is cautious to give to a diabetic patient

[x] 43 years old hypertensive man suffer from enlarged prostate,the most suitable drug to give is(most suitable)