M&r Review By : Kmsa-med

21 Questions | By KUFAMEDST | Last updated: Mar 21, 2022 | Total Attempts: 79

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1.

Procaine mechanism of action is
- A.
  
  Blocking Na channel
- B.
  
  Blocking Na pump
- C.
  
  Blocking Ca channel
- D.
  
  Activating k channel
2.

Na Ca exchanger consider a :-
- A.
  
  Secondary active antiport
- B.
  
  Secondary active symport
- C.
  
  Primary active
- D.
  
  Ligand gated channel
3.

Capacitance of large unmyelinated fiber is :-
- A.
  
  Higher than that of large myelinated fibers
- B.
  
  Lower than that of myelinated fiber
- C.
  
  Equal to capacitance of myelinated fibers
- D.
  
  None of above
4.

C sensory fibers have a characteristics of :-
- A.
  
  Low resistance and high capacitance
- B.
  
  High capacitance and high resistance
- C.
  
  High resistance and low capacitance
- D.
  
  Low resistance and low capacitance
5.

V2 vasopressin receptors, activated by ------- . And located in------
- A.
  
  ADH , kidney
- B.
  
  ADH , blood vessels
- C.
  
  Angiotensin 2 , kidney
- D.
  
  Angiotensin 2 , blood vessels
6.

Increase membrane Cl permeability results in :-
- A.
  
  Difficulty to initiate a stimulatory action potential
- B.
  
  Increase cell excitability
- C.
  
  Block K channel
- D.
  
  Decrease Na pumping activity
7.

Prolonged usage of loop diuretic may cause :-
- A.
  
  Hypokalemia
- B.
  
  Hyperkalemia
- C.
  
  Hypocalcemia
- D.
  
  Hypercalcemia
8.

Years old patient presented with fever and rectal temperature of 38.3 what would you predict about membrane cholesterol role in that patient :-
- A.
  
  Decrease fluidity
- B.
  
  Increase fluidity
- C.
  
  Increase permeability
- D.
  
  Both second and third choice
9.

Glycine mechanism of action is :-
- A.
  
  Inhibitory post synaptic potential
- B.
  
  Excitatory post synaptic potential
- C.
  
  Na channel blocker
- D.
  
  K channel blocker
10.

One of the followings is not a neurotransmitter
- A.
  
  DAG
- B.
  
  Glycine
- C.
  
  Dopamine
- D.
  
  Acetylcholine
11.

Apotransferrin dissociate from its receptors at
- A.
  
  Neutral PH
- B.
  
  Low PH
- C.
  
  High Fe level
- D.
  
  Low Fe level
12.

Asthmatic pt due to allergy(allergic asthma) You prefer to give him
- A.
  
  Beclomethasone
- B.
  
  Diphenhydramine
- C.
  
  Antihistamine
- D.
  
  Cromoglycate
13.

B blocker help hypertensive by several mechanisms except
- A.
  
  Vasodilation
- B.
  
  Decrease SV
- C.
  
  -ve chronotropic effect
- D.
  
  Inhibition of renin system
14.

These substances help in lowering of HT except
- A.
  
  Methoxamine
- B.
  
  Clonidine
- C.
  
  Guanethedine
- D.
  
  Insecticide organophosphorous
15.

[x] This drug is cautious to give to a diabetic patient
- A.
  
  Propanolol
- B.
  
  Dopamine
- C.
  
  Prazosin
- D.
  
  Clonidine
16.

[x] 43 years old hypertensive man suffer from enlarged prostate,the most suitable drug to give is(most suitable)
- A.
  
  Prazosin
- B.
  
  Dobutamine
- C.
  
  Salbutamol
- D.
  
  Tamsulusin
17.

These drugs are used treatment of glaucoma except
- A.
  
  Dobutamine
- B.
  
  Timolol
- C.
  
  Pilocarpine
- D.
  
  Apraclonidine
18.

[x] If A is suddenly withdrawn after chronic use and the patient has inverse symptoms like tachycardia, hypertension...You think A is....bcz ....
- A.
  
  Metaprolol,up regulation
- B.
  
  Salbutamol,up regulation
- C.
  
  Dobutamine,down regulation
- D.
  
  Yohimbine,up regulation
19.

Drug's side effects tend to become less intense with time , even though drug administration is continued due to :-
- A.
  
  Physiological adaptation
- B.
  
  Receptor conformational changes
- C.
  
  Numerical down regulation
- D.
  
  Exhaustion of mediators
20.

The inverse agonist has Emax.............while antagonist Emax is..............
- A.
- B.
  
  0,
- C.
  
  >0,>0.
- D.
21.

An case with MI due occlusion of one of coronary arteries due to thrombus has given warfarin, before coming to A&E he took allopurinol as treatment of gout arthritis and erythromycin as treatment of Tonsillitis drug interaction of drugs may lead to : .
- A.
  
  Bleeding
- B.
  
  Another thrombus
- C.
  
  Angina
- D.
  
  HyperAcute