Uhs ,Tsmc, MCQ , Immunology For Medical Lab Year 3 Semester 2,

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Uhs ,Tsmc, MCQ , Immunology For Medical Lab Year 3 Semester 2, - Quiz

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Questions and Answers
  • 1. 

    ការធ្វើរោគវិនិច្ឆិយនៃជំងឺឆ្លង ដោយប្រើបច្ចេកទេសសេរ៉ូសាស្រ្តគឺ

    • A.

      កំណត់នៅមេរោគដែលបង្ករជំងឺ

    • B.

      កំណត់នូវ Ab ដែលបង្កើតឡើងទប់ទល់ទៅនឹងមេរោគ

    • C.

      កំណត់នូវកំហាប់នៃ Ab នឹងAg នៅក្នុងឈាម

    • D.

      កំណត់នួវ៖មេរោគបង្កជំងឺប្រភេទAb និង កំហាប់ AgនឹងAb ក្នុងខ្លួន

    Correct Answer
    D. កំណត់នួវ៖មេរោគបង្កជំងឺប្រភេទAb និង កំហាប់ AgនឹងAb ក្នុងខ្លួន
    Explanation
    The explanation states that the diagnosis of the disease involves determining the presence of Ab (antibodies) and the concentration of Ag (antigen) in the body. This suggests that the immune system is producing antibodies in response to the antigen, which indicates the presence of the disease. Therefore, the correct answer is that the diagnosis of the disease involves detecting the type of Ab and the concentration of Ag in the body.

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  • 2. 

    ៤.​តើ Antigen បង្ករឡើងដោយសារ អ្វី?

    • A.

      ប្រួតេអ៊ីន ប៉ូលីសាខារីត នុក្លេអ៊ីចអាស៊ីត

    • B.

      អាស៊ីតនុយក្លេអ៊ិច (Nucleic Acids)

    • C.

      ប៉ុលីសាខារីត (Polysaccharides)

    • D.

      ប្រូតេអ៊ីន (Proteins)

    Correct Answer
    A. ប្រួតេអ៊ីន ប៉ូលីសាខារីត នុក្លេអ៊ីចអាស៊ីត
    Explanation
    Antigens are substances that can stimulate an immune response in the body. They can be proteins, polysaccharides, nucleic acids, or lipids. In this case, the correct answer is "Bacteria, pollen, and viruses" which are examples of antigens that can trigger an immune response.

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  • 3. 

    ៣.​​ ខាងក្រោមនេះជាលក្ខណះរបស់ Immuno-Precipitation assays ​លើកលែងតែៈ 

    • A.

      រក Ab ឯករាជ្យមិនមានជាប់ទៅនឹងអ្វី

    • B.

      កំណង់នូវ Ab មាននៅក្នុងខ្លួន

    • C.

      ប្រើAg ឯករាជ្យដែលមិនភ្ជាប់នឹងអ្វី

    • D.

      កំណត់នូវចំនួន Ab ដែលមានក្នុងខ្លួន

    Correct Answer
    D. កំណត់នូវចំនួន Ab ដែលមានក្នុងខ្លួន
    Explanation
    This answer states that the purpose of the Immuno-Precipitation assay is to determine the quantity of antibodies present in a sample. This is done by using an antigen that does not bind to anything else and measuring the amount of antibodies that bind to it. The answer correctly identifies that the assay is used to quantify the antibodies present in the sample.

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  • 4. 

    ៥. តើកត្តាអ្វីដែលមានឥទ្ធិពលលកការធ្វើវិភាគដោយប្រើរូបមន្ត Agglutination tests?

    • A.

      កំហាប់នៃ Ab(Concentration of Ab)

    • B.

      កំដៅ (Temperature)

    • C.

      កំដៅ កំហាប់នៃ Ab, អាស៊ីត pH

    • D.

      អាស៊ីត pH

    Correct Answer
    C. កំដៅ កំហាប់នៃ Ab, អាស៊ីត pH
  • 5. 

    ៦. ប្រយោគខាងក្រោមនេះមួយណាដែលមិនត្រឺមត្រូវសំរាប់ រួបមន្តការធ្វើតេស្ត Agglutination?

    • A.

      កំណត់នូវក្រុមឈាម

    • B.

      រាប់មេរោគដែលមានក្នុងឈាម

    • C.

      កំណត់កំហាប់ Ab ក្នុងឈាម

    • D.

      កំណត់ប្រភេទរកមេរោគបង្ករជំងឺ

    Correct Answer
    B. រាប់មេរោគដែលមានក្នុងឈាម
    Explanation
    The correct answer states that the presence of pathogens in semen is responsible for agglutination. Agglutination refers to the clumping together of particles, in this case, the pathogens in the semen. This clumping can occur due to the presence of antibodies that bind to the pathogens, causing them to stick together. Therefore, the correct answer suggests that the pathogens present in semen are responsible for the agglutination phenomenon.

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  • 6. 

    ៧.​ ដើម្បីដឹងថាប្រតិករតេស្ត Serology ​ដែលទទួលបានថ្មីមានគុណភាពល្អលើការធ្វើវិភាគអ្នកមន្ទីរពិ​សោធន៍ត្រូវតែ

    • A.

      ពិនិត្យមើនថ្ងៃកំណត់នៃការប្រើប្រាស់ ស្ថានភាពនៃកញ្ចប់តេស្ត

    • B.

      បរិយាកាសការរក្សាទុកទៅតាមការណែនាំរបស់តេស្ត

    • C.

      ត្រូវធ្វើវិភាគសេរ៉ូមក្រុងត្រូលដែលដឹងលទ្ធផលជាមុន (Pos and Neg controls)

    • D.

      ពិនិត្យកញ្ចប់តេស្ត ថ្ងៃកំណត់ប្រើ វិភាគតាមការណែនាំនៃតេស្តនិងមានតេស្តកុងត្រូលផងដែរ

    Correct Answer
    D. ពិនិត្យកញ្ចប់តេស្ត ថ្ងៃកំណត់ប្រើ វិភាគតាមការណែនាំនៃតេស្តនិងមានតេស្តកុងត្រូលផងដែរ
    Explanation
    To ensure the accuracy of serological testing, it is important to perform quality control measures. This includes conducting a preliminary evaluation of the test's performance before its official use, assessing the condition of the sample, following proper testing protocols, and including positive and negative controls in the analysis. Additionally, it is crucial to validate the test results by comparing them with the results from other reliable tests and confirming the presence or absence of specific antibodies or antigens. By following these steps, the serological testing can provide reliable and accurate information about an individual's immune response.

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  • 7. 

    ៨. នៅក្នុងតេស្ត Serodia HBs Ag ល្បាយសូលុស្យុង "D" គឺជា៖

    • A.

      Control Cells

    • B.

      Control Positive

    • C.

      Control Negative

    • D.

      Sample diluent

    Correct Answer
    A. Control Cells
  • 8. 

    ៩. ខាងក្រោមនេះជាប្រភេទបច្ចេកទេសដែលប្រើការភ្ជាប់ប្រតិករ (Ab)ទៅនឹង Enzyme ឬFluorescence Dye ឬ Radioactive isotope, លើកលែងតែ៖

    • A.

      Radio immunoassay

    • B.

      Enzyme Immunoassays

    • C.

      Immunofixation

    • D.

      Immuno-fluorescence

    Correct Answer
    C. Immunofixation
    Explanation
    Immunofixation is the correct answer because it is a type of immunoassay that uses the binding of antibodies to specific antigens to detect and identify proteins. It involves the use of antibodies labeled with fluorescent dyes or radioactive isotopes to visualize the protein-antibody complexes. This technique is commonly used in clinical laboratories to diagnose and monitor various diseases, such as multiple myeloma and other immunoglobulin disorders.

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  • 9. 

    ១០. តើខាងក្រោមនេះមួយណាត្រឹមត្រូវជាង ទៅលើការអានសទ្ធភលនៃតេស្តSerodia? 

    • A.

      ដល់ម៉ោងកំណត់អានលទ្ធផល

    • B.

      នៅពេលដែលកុងត្រូល Paticle/Cell ធ្លាក់ដល់កំរិត

    • C.

      ពិនិត្យេមើលែតរុន្ធ របស់ Sensitized

    • D.

      ដល់ម៉ោងកំណត់រួចពិនិត្យរុន្ធ Sensitized/ Non sensitized

    Correct Answer
    D. ដល់ម៉ោងកំណត់រួចពិនិត្យរុន្ធ Sensitized/ Non sensitized
    Explanation
    This answer suggests that the correct step in the process of reading the Serodia test results is to evaluate the sensitized and non-sensitized reactions at the specified time. This step is important in determining the presence or absence of antibodies in the patient's blood.

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  • 10. 

    ១១. តើតេស្តរហ័ស Determine HIV1/2 ឬ Determine HBs-Ag ជាតេស្តប្រភេទអ្វី?

    • A.

      Precipitation tests

    • B.

      Immunochromatographic tests

    • C.

      Passive Agglutination testes

    • D.

      Immunofixation

    Correct Answer
    B. Immunochromatographic tests
    Explanation
    Immunochromatographic tests are used to determine the presence of specific antibodies or antigens in a sample. These tests work by using a strip or cassette that contains a specific antibody or antigen. When the sample is applied to the strip, it migrates along the strip and interacts with the immobilized antibody or antigen. If the target antibody or antigen is present in the sample, it will bind to the immobilized antibody or antigen, resulting in a visible line or signal. This type of test is commonly used for rapid and point-of-care diagnostics, including the determination of HIV1/2 or HBs-Ag.

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  • 11. 

    ១២. ការធ្វើតេស្តកុងត្រូល វីជ្ជមាននិងអវិជ្ជមាន នៅគ្រប់ពេលធ្វើតេស្ត Serodia តេស្តរប័សគឺ៖

    • A.

      ចំណាយប្រតិករឥតប្រយោជន៍

    • B.

      សំរាប់ផ្ទៀងផ្ទាត់លទ្ធផលមួយលទ្ធផលអ្នកជំងឺ

    • C.

      បង្កើននូវទំនុកចិត្តិនិងភាពត្រឹមត្រូវការធ្វើវិភាគ

    • D.

      ពិនិត្យគុណភាពតេស្ត ផ្ទៀងផ្ទាត់លទ្ធផលអ្នកជំងឺ និងទំនុកចិត្តិ

    Correct Answer
    D. ពិនិត្យគុណភាពតេស្ត ផ្ទៀងផ្ទាត់លទ្ធផលអ្នកជំងឺ និងទំនុកចិត្តិ
    Explanation
    The correct answer is to evaluate the accuracy of the test results and the reliability of the test. By assessing the quality of the test, it ensures that the results obtained are reliable and can be used to make accurate diagnoses. This is important in order to provide appropriate treatment and care for patients. Additionally, evaluating the performance of the test helps to identify any areas for improvement and to optimize the testing process.

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  • 12. 

    ១៣. ខាងក្រោមនេះជាសំភារះសំរាប់ធ្វើវិភាគ Rheumatoid Factor (Biotech)-FR, លើកលែងតែ៖

    • A.

      Pipette tips

    • B.

      Microplate

    • C.

      Disposal glove

    • D.

      Card tests

    Correct Answer
    B. Microplate
    Explanation
    The correct answer is "Microplate". The question is asking for a suitable tool for performing the Rheumatoid Factor (Biotech)-FR test. Out of the options given, a microplate is the most appropriate choice as it is commonly used in laboratory settings for conducting various tests, including immunoassays. A microplate consists of multiple wells that can hold small volumes of samples, reagents, and controls, allowing for efficient and simultaneous testing of multiple samples.

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  • 13. 

    ១៤. តើតេស្តសំរាប់រកAnti Stretolysin O (ASO)តេស្តប្រភេទអ្វី?

    • A.

      Agglutination Inhibitor

    • B.

      Haemagglutination test

    • C.

      Latex Passive Agglulination test

    • D.

      Immuno Fixation

    Correct Answer
    C. Latex Passive Agglulination test
    Explanation
    The correct answer is "Latex Passive Agglutination test". This test is used to detect the presence of Anti-Streptolysin O (ASO) antibodies in the blood. In this test, latex particles coated with Streptolysin O antigen are mixed with the patient's serum. If ASO antibodies are present in the serum, they will bind to the latex particles, causing them to clump together, indicating a positive result. This test is commonly used to diagnose a recent or past Streptococcal infection.

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  • 14. 

    ១៥. តេស្ត ASO (Anti-Striptolysis O) ដោយប្រើប្រតិកររបស់ Biotech វិភាគលទ្ធផលបង្ហាញថាប្រតិកម្ម ទៅនឹងពង្រាវ ១/៨ តើលទ្ធផលខាងក្រោមនេះមួយណាដែលត្រឹមត្រូវ?

    • A.

      48 mg/mL

    • B.

      64 IU/mL

    • C.

      128 IU/mL

    • D.

      1600 IU/mL

    Correct Answer
    D. 1600 IU/mL
    Explanation
    The correct answer is 1600 IU/mL. This is because the question states that the ASO test result using Biotech's reagent shows a correlation of 1/8 with the titer. This means that the titer is 8 times higher than the result obtained from the ASO test. Therefore, to find the titer, we need to multiply the ASO test result by 8. In this case, the ASO test result is 200 IU/mL (1600/8), which is equal to 1600 IU/mL.

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  • 15. 

    ១៦. តេស្ត FR (Factor Rheumatoid)ដោយប្រើប្រតិកររបស់ Biotech វិភាគលទ្ធផលបង្ហាញថាប្រតិកម្ម ទៅនឹងពង្រាវ ១/៨ តើលទ្ធផលខាងក្រោមនេះមួយណាដែលត្រឹមត្រូវ?

    • A.

      48 mg/mL

    • B.

      64 IU/mL

    • C.

      128 IU/mL

    • D.

      800 IU/mL

    Correct Answer
    B. 64 IU/mL
    Explanation
    Biotech's Factor Rheumatoid test shows that the factor is present in a concentration of 64 IU/mL.

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  • 16. 

    ១៧. តេស្ត CRP (C-Reaction Protein)ដោយប្រើប្រតិកររបស់ Biotech វិភាគលទ្ធផលបង្ហាញថាប្រតិកម្ម ទៅនឹងពង្រាវ ១/៨ តើលទ្ធផលខាងក្រោមនេះមួយណាដែលត្រឹមត្រូវ?

    • A.

      48 mg/mL

    • B.

      64 IU/mL

    • C.

      128 IU/mL

    • D.

      800 IU/mL

    Correct Answer
    A. 48 mg/mL
    Explanation
    CRP (C-Reaction Protein) is a biomarker that is used to measure the level of inflammation in the body. The given answer of 48 mg/mL suggests that the concentration of CRP in the sample is 48 milligrams per milliliter. This indicates a moderate level of inflammation.

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  • 17. 

    ១៨.​ តើវត្ថុវិភាគណាខ្លះដែលគេណែនាំអោយប្រើសំរាប់ធ្វើវិភាគជាមួយនឹងតេស្តប្រភេទ Serodia?

    • A.

      ទឹកខួរឆ្អឹងខ្នង (CSF)

    • B.

      សេរ៉ូម (Serum)

    • C.

      ឈាមស្រស់ (Whold blood)

    • D.

      ផ្លាស្មា និងសេរ៉ូំម ឈាម (Plasma and serum)

    Correct Answer
    D. ផ្លាស្មា និងសេរ៉ូំម ឈាម (Plasma and serum)
    Explanation
    The question is asking which body fluid is commonly used for serological testing using the Serodia method. The correct answer is "Plasma and serum." Serodia is a serological test that detects antibodies in the blood. Both plasma and serum can be used for this type of testing as they contain antibodies. Plasma is the liquid portion of blood that is obtained when blood is anticoagulated, while serum is the liquid portion of blood obtained after coagulation. Both plasma and serum are commonly used in serological testing as they contain the necessary antibodies for detection.

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  • 18. 

    ១៩. តើវត្ថុវិភាគណាខ្លះដែលគេណែនាំអោយប្រើសំរាប់វិភាគជាមួយនឹងតេស្តប្រភេទ Rapid testsឬ Lateral flow បាន?

    • A.

      ទឹកខួរឆ្អឹងខ្នង (CSF)

    • B.

      សេរ៉ូមឈាម

    • C.

      ឈាមស្រស់ (Whold blood)

    • D.

      សេរ៉ូម ផ្លាស្មា និងឈាមស្រស់

    Correct Answer
    D. សេរ៉ូម ផ្លាស្មា និងឈាមស្រស់
  • 19. 

    ២០. ភាពត្រឹមត្រូវនៃការចេញលទ្ធផលតេស្តវិជ្ជមានបាន អ្នកធ្វើវិភាគត្រូវតែៈ 

    • A.

      ពិនិត្យទៅលើតេស្តអ្នកជំងឺថាមានប្រតិកម្មឬអត់ ហើយផ្ទៀងផ្ទាត់ទៅនឹងកុងត្រូល

    • B.

      ពិនិត្យទៅលើតែតេស្តអ្នកជំងឺថាមានប្រតិកម្មឬអត់

    • C.

      ធ្វើតេស្តកុងត្រូលរៀងរាល់ថ្ងៃតេស្ត

    • D.

      ត្រូវពិនិត្យទាំងពីរ (កុងត្រូលនឹងតេស្ត) មានប្រតិកម្មឬអត់ & ត្រូវធ្វើតេស្តកុងត្រូលជាប្រចាំរាល់ថ្ងៃវិភាគឈាមអ្នកជំងឺ

    Correct Answer
    D. ត្រូវពិនិត្យទាំងពីរ (កុងត្រូលនឹងតេស្ត) មានប្រតិកម្មឬអត់ & ត្រូវធ្វើតេស្តកុងត្រូលជាប្រចាំរាល់ថ្ងៃវិភាគឈាមអ្នកជំងឺ
    Explanation
    The correct answer is to check both the hormone levels (estrogen and testosterone) and to perform regular breast examinations. This is because hormonal imbalances can contribute to the development of breast cancer, and it is important to monitor both estrogen and testosterone levels. Additionally, regular breast examinations can help detect any abnormalities or changes in the breast tissue, which can be indicative of breast cancer.

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  • 20. 

    ខាងក្រោមនេះជាបច្ចេកទេស / រួបមន្ត Serologyសំរាប់កំណត់ឬរកប្រភេទdiseaseលើកលែងតែ

    • A.

      Precipitation technique

    • B.

      Sequencing technique

    • C.

      Agglutination technique

    • D.

      Chemiluminescent technique

    Correct Answer
    B. Sequencing technique
    Explanation
    The sequencing technique is used to determine the exact order of nucleotides in a DNA or RNA molecule. This technique allows scientists to identify the specific sequence of genetic material, which can be used to diagnose diseases, study genetic variations, and understand the structure and function of genes. It involves the use of specialized equipment and methods to read and interpret the sequence of nucleotides. This technique is different from the other techniques mentioned, such as precipitation, agglutination, and chemiluminescent techniques, which are used for different purposes in serology.

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  • 21. 

    តើប្រយោគខាងក្រោមនេះណាមួយត្រឹមត្រូវជាងគេទៅលើការធ្វើវិភាគរោគវិនិឆ្ឋ័យនៅក្នុងមន្ទីពិសោធន៏ហើយទទួលបានលទ្ធផលល្អ?

    • A.

      មានវត្ថុវិភាគល្អ និងប្រតិករល្អ

    • B.

      បន្ទប់ពិសោធន៏ស្អាត និង ប្រតិករល្អ

    • C.

      សំភារះនិងឧបករណ៏ត្រឹមត្រូវ វត្ថុវិភាគ និងប្រតិករល្អ

    • D.

      មានជំនាញយល់ច្បាស់ពីគោលការណ៏នៃតេស្ត សំភារះនិងឧបករណ៏ត្រឹមត្រូវ,វត្ថុវិភាគ និង ប្រតិករល្អ

    Correct Answer
    D. មានជំនាញយល់ច្បាស់ពីគោលការណ៏នៃតេស្ត សំភារះនិងឧបករណ៏ត្រឹមត្រូវ,វត្ថុវិភាគ និង ប្រតិករល្អ
    Explanation
    This answer states that having a good understanding of the subject matter, clear and relevant arguments, and effective presentation skills are important factors for achieving good results in academic research. It suggests that having a deep understanding of the topic, being able to analyze and discuss the issues, and presenting the findings in a coherent and convincing manner are key to obtaining good outcomes in academic research.

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  • 22. 

    ជាធម្មតាការចំលងការចំលងតាមលាមក តាមផ្លូវអាហារ គឺជាការចំលងរបស់មេរោគណាមួយខាងក្រោម(The fecal/oral route is the common transmission for) 

    • A.

      HAV និង HEV

    • B.

      HBV/HDV

    • C.

      HCV

    • D.

      HVE

    Correct Answer
    A. HAV និង HEV
    Explanation
    HAV and HEV are transmitted through the fecal/oral route, which means that the viruses are present in the feces of infected individuals and can be transmitted to others through contaminated food, water, or objects. This mode of transmission is common for these viruses because they can survive in the environment and remain infectious for extended periods of time. In contrast, HBV, HDV, HCV, and HVE are primarily transmitted through blood and bodily fluids, such as through sexual contact, sharing needles, or from mother to child during childbirth.

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  • 23. 

    ការកំណត់ បើសិនអ្នកជំងឺមានមេរោគរលាកថ្លើមសេអ្នកគួរចាប់ផ្ដើមធ្វើតេស្ដសំរាប់(To determine if a patient has HCV, you could start with tests for:)

    • A.

      ALT and anti-HCV

    • B.

      Anti-HIV

    • C.

      Anti-HBc

    • D.

      HBs Ag

    Correct Answer
    A. ALT and anti-HCV
    Explanation
    ALT and anti-HCV are the appropriate tests to determine if a patient has HCV. ALT (Alanine aminotransferase) is an enzyme found in the liver, and elevated levels of ALT in the blood may indicate liver damage, which can be caused by HCV infection. Anti-HCV refers to antibodies against the hepatitis C virus, and the presence of these antibodies in the blood indicates a current or past HCV infection. Therefore, by testing for both ALT and anti-HCV, healthcare professionals can assess liver function and detect the presence of HCV in a patient.

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  • 24. 

    សេរ៉ូមរបស់អ្នកដែលបានចាក់វ៉ាក់សាំងសំរាប់វិរ៉ុស Hepatitis Bគឺជាលទ្ធផល(The serum of someone that has been vaccinated for Hepatitis B virus will be)

    • A.

      Positive for Anti-HBc IgM

    • B.

      Positive for HBeAg

    • C.

      Positive for anti-HBsAg

    • D.

      Positive for anti-HBeAg

    Correct Answer
    C. Positive for anti-HBsAg
    Explanation
    The correct answer is "positive for anti-HBsAg". When someone is vaccinated for Hepatitis B, their serum will test positive for anti-HBsAg, which indicates the presence of antibodies against the surface antigen of the Hepatitis B virus. This is a desirable result, as it means that the person has developed immunity against the virus. The other options listed (positive for Anti-HBc IgM, positive for HBeAg, positive for anti-HBeAg) are not indicative of a successful vaccination.

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  • 25. 

    ជាទូទៅវីរុស Hepatitis B​ឆ្លងតាមរយះឈាមនៅពេលដែលឈាមមាន(HBV is transmitted most frequently with blood that is:

    • A.

      Positive for Anti-HBs Ag

    • B.

      Positive for HBeAg

    • C.

      Positive for anti-HBeAg

    • D.

      Negative for p24 Ag

    Correct Answer
    B. Positive for HBeAg
    Explanation
    Hepatitis B virus (HBV) is most commonly transmitted through blood that is positive for HBeAg. HBeAg is a marker of active viral replication and indicates a high level of infectiousness. When blood is positive for HBeAg, it means that the person is highly contagious and can easily transmit the virus to others. Therefore, this is the most likely mode of transmission for Hepatitis B.

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  • 26. 

    អ្នកជំងឺដែលមានជំងឺរាំរ៉ៃសកម្មជាទូទៅ Hepatitis Bជាទូទៅនៅក្នុងឈាមឃើញមាន(Patients with chronic active Hepatitis B virus will most likely have measurable of:)

    • A.

      HBs Ab

    • B.

      HBe Ab

    • C.

      HBs Ag

    • D.

      IgG HBs Ab

    Correct Answer
    C. HBs Ag
    Explanation
    Patients with chronic active Hepatitis B virus will most likely have measurable levels of HBs Ag, which stands for Hepatitis B surface antigen. HBs Ag is a protein on the surface of the Hepatitis B virus and is used to diagnose and monitor the infection. HBs Ab (Hepatitis B surface antibody) is produced by the immune system in response to the virus and indicates immunity or past infection. HBe Ab (Hepatitis B e antibody) is an antibody that develops during the early stages of infection. IgG HBs Ab refers to the IgG class of antibodies against HBs Ag.

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  • 27. 

    តើតេស្តHepatitis Bអ្វីដែលរកឃើញវិជ្ជមាននៅដំណាក់កាលចាប់ផ្ដើមឆ្លងស្រួចស្រាវ?What hepatitis B markers are detected in early acute infection?

    • A.

      HBs-Ag និង Anti-HBs

    • B.

      HBe-Ag និង Anti-HBs

    • C.

      HBs-Ag និង IgM anti-HBc

    • D.

      HBc-Ag និង Anti-HBe

    Correct Answer
    C. HBs-Ag និង IgM anti-HBc
    Explanation
    In early acute infection of Hepatitis B, the markers HBs-Ag (Hepatitis B surface antigen) and IgM anti-HBc (IgM antibody to Hepatitis B core antigen) are detected. HBs-Ag is a protein on the surface of the Hepatitis B virus, and its presence indicates active infection. IgM anti-HBc is an antibody produced in response to the core antigen of the virus, and its presence indicates recent infection. The other options listed do not include both HBs-Ag and IgM anti-HBc, which are the markers typically detected in early acute infection.

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  • 28. 

    តើតេស្តអ្វីដែលវិជ្ជមាននៅលើមនុស្សដែលបានជាដោយឯកឯងពីការឆ្លងមេរោគHBV?What markers are detected in a person who has recovered from HBV infectinon?

    • A.

      Anti-HBs និង Anti-HBc IgM

    • B.

      Anti-HBs និង Anti-HBe

    • C.

      Anti-HBc IgM និង Anti-HBe

    • D.

      Anti-HBc IgG និង Anti-HBs

    Correct Answer
    D. Anti-HBc IgG និង Anti-HBs
  • 29. 

    តើ Marker ណាមួយខាងក្រោមនេះនៃមេរោគរលាកថ្លើមប្រភេទបេ(HBV)ដែលគេមិនអាចវិភាគលើសេរ៉ួសាស្ត្របាន?

    • A.

      HBc Total

    • B.

      HBc-Ag

    • C.

      HBe-Ag

    • D.

      HBs-Ag

    Correct Answer
    B. HBc-Ag
    Explanation
    HBc-Ag refers to the hepatitis B core antigen. This antigen is not detectable in the blood of individuals infected with the hepatitis B virus (HBV) who are in the window period, which is the time between the disappearance of HBsAg (hepatitis B surface antigen) and the appearance of anti-HBs (hepatitis B surface antibody). During this period, HBc-Ag is the only marker that can be detected, making it the correct answer.

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  • 30. 

    50. តើតេស្តប្រភេទណាខាងក្រោមនេះ​មានលក្ខណះជាក់លាក់ខ្លាំងសំរាប់ការរោគវិនិច្ឆ័យរក​Ab នៃមេរោគអេដស៏?

    • A.

      Serodia

    • B.

      Wester Blot Tests

    • C.

      PCR quantitative tests

    • D.

      PCR qualitative test

    Correct Answer
    B. Wester Blot Tests
    Explanation
    Western Blot Tests are known for their high sensitivity in detecting specific antibodies, making them effective in diagnosing diseases caused by Ab (antibodies) such as HIV, Lyme disease, and certain types of cancer. This test involves separating proteins by size using gel electrophoresis and then transferring them to a membrane for antibody detection. The strong binding affinity of antibodies in Western Blot Tests makes them highly reliable for identifying specific antibodies in a sample.

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  • 31. 

    51. ពេលដែលដឺងថាអ្នកណាម្នាក់ប្រឈមនឺងការឆ្លងមេរោគអេដស៏​(ប្រហែល១ខែ)​តើអ្នកត្រូវណែនាំអោយគាត់ធ្វើតេស្តអ្វីដែលត្រឺមត្រូវ​សំរាប់មើលនូវការឆ្លងនៃមេរោគ?

    • A.

      Immunochromatographic tests

    • B.

      PCR qualitative test

    • C.

      PCR quantitative test

    • D.

      Wester Blot (WB) test

    Correct Answer
    B. PCR qualitative test
    Explanation
    The correct answer is PCR qualitative test. This test is recommended when someone suspects that they have been infected with a particular pathogen, such as HIV. It is used to detect the presence or absence of the pathogen's genetic material in a person's sample. This test can provide a yes or no answer regarding the presence of the pathogen, but it does not provide information about the quantity or amount of the pathogen in the sample.

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  • 32. 

    52. ដើម្បីបកស្រាយលទ្ធផលតេស្តនិមួយៗ​បានត្រឺមត្រូវ អ្នកមន្ទីរពិសោធន៏​ត្រូវតែ:

    • A.

      មានចំណេះដឺងទូទៅពីមន្ទីរពិសោធន៏ជ្រៅជ្រះ

    • B.

      យល់ច្បាស់ពីគោលការណ៏នៃតេស្តនិមួយបានច្បាស់លាស់

    • C.

      ជាអ្នកបច្ចេកទេសមន្ទីរពិសោធន៏

    • D.

      អ្នកមានជំនាញយូរឆ្នាំនៅក្នុងមន្ទីរពិសោធន៏

    Correct Answer
    B. យល់ច្បាស់ពីគោលការណ៏នៃតេស្តនិមួយបានច្បាស់លាស់
    Explanation
    To accurately solve each question, the examiner must have a good understanding of the subject matter. In this case, the correct answer suggests that the examiner should have a deep understanding of the principles and concepts related to the specific topic. This knowledge will allow them to accurately interpret and analyze the given data or information, enabling them to arrive at the correct solution.

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  • 33. 

    53. តើសមាសធាតុមួយណានៅក្នុងតេស្ត​ELISA ដែលប្រើសំរាប់បញ្ឈប់ប្រតិកម្មបំឡែងនៃEnzyme របស់វាគឺ

    • A.

      Conjugate

    • B.

      Buffered solution

    • C.

      Acid solution

    • D.

      Substrate

    Correct Answer
    C. Acid solution
    Explanation
    The correct answer is "Acid solution". In ELISA, the acid solution is used to stop the enzyme reaction and terminate the assay. This is done by changing the pH of the solution, which inactivates the enzyme and prevents further substrate conversion. By adding an acid solution, the enzyme activity is effectively stopped, allowing for accurate measurement of the reaction.

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  • 34. 

    54. ការធ្វើតេស្តELISA សំរាប់HIV-1 និងឃើញលទ្ធផលរបស់កុងត្រូលវិជ្ជមានទៅជាអវិជ្ជមាន

    • A.

      យល់ព្រមទៅលើលទ្ធផលតេស្តរបស់អ្នកជំងឺអវិជ្ជមាន

    • B.

      ធ្វើតេស្តឡើងវិញគ្រប់វត្ថុវិភាគអ្នកជំងឺដែលមានលទ្ធផលតេស្តអវិជ្ជមាន

    • C.

      ធ្វើតេស្តឡើងវិញគ្រប់វិភាគអ្នកជំងឺដែលមានលទ្ធផលតេស្តវិជ្ជមាន

    • D.

      ធ្វើតេស្តឡើងវិញគ្រប់វិត្ថុភាគរបស់អ្នកជំងឺ

    Correct Answer
    D. ធ្វើតេស្តឡើងវិញគ្រប់វិត្ថុភាគរបស់អ្នកជំងឺ
    Explanation
    The correct answer suggests that the ELISA test should be repeated for all the different components of the patient's blood in order to confirm the presence of HIV-1 and obtain accurate results. This ensures that all aspects of the test are thoroughly examined and any potential errors or inconsistencies are minimized.

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  • 35. 

    55. នៅក្នុងតេស្តELISA , ប្រតិកម្មនៃEnzyme នៃsubstrate បណ្ដាលអោយមានការដូរពណ៏ដែលពណ៏នោះសមាមាត្រទៅនឺង

    • A.

      HIV-1/2 Ags របស់អ្នកជំងឺចាប់ទៅនឹង Ab to HIV-1/2 នៃតេស្ត

    • B.

      HIV-1/2 Abs របស់អ្នកជំងឺចាប់នឺងទៅនឹង Ag to HIV -1/2

    • C.

      ក្នុងចំនួននៃSubstrate (amount of substrate)

    • D.

      ក្នុងចំនួននៃលទ្ធផលរាប់វិរុស amount of viral load result

    Correct Answer
    B. HIV-1/2 Abs របស់អ្នកជំងឺចាប់នឺងទៅនឹង Ag to HIV -1/2
    Explanation
    In ELISA, the enzyme of the substrate changes color based on the color of the substrate. The amount of substrate used corresponds to the amount of viral load result. Therefore, the answer is that the HIV-1/2 Abs of the patient will react with the Ag to HIV-1/2.

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  • 36. 

    56. ការធ្វើវិភាគរាប់កោសិកាCD4សំរាប់:

    • A.

      រកមេរោគអេដស៏

    • B.

      កំណត់នូវស្ថានភាពប្រពន្ធភាពសាំុរបស់អ្នកជំងឺ

    • C.

      តាមដានការព្យាបាលជាមួយនឹងមេរោគអេដស៏

    • D.

      កំណត់នូវកំរិតភាពសាំុនិងតាមដានការព្យាបាលនឹងមេរោគអេដស៏

    Correct Answer
    D. កំណត់នូវកំរិតភាពសាំុនិងតាមដានការព្យាបាលនឹងមេរោគអេដស៏
    Explanation
    This answer states that CD4 count and monitoring of immune function are important for determining the severity of HIV infection and assessing the progression of the disease. CD4 count is a measure of the number of CD4 T cells in the blood, which are a key component of the immune system. Monitoring CD4 count can help determine the level of immune suppression and guide treatment decisions. Additionally, monitoring for signs and symptoms of opportunistic infections and assessing the level of immune activation can provide further information about the progression of HIV infection.

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  • 37. 

    57. ខាងក្រោមនេះតើមួយណាជាបច្ចេកទេសដែលប្រើសំរាប់រាប់កោសិកា​ CD4?

    • A.

      Hematology analyzer

    • B.

      Chemiluomination assay

    • C.

      Flow cytometry

    • D.

      Real-time PCR

    Correct Answer
    C. Flow cytometry
    Explanation
    Flow cytometry is a technique commonly used to measure the number of CD4 cells in a blood sample. It involves labeling the CD4 cells with fluorescent antibodies and passing them through a flow cytometer, which can detect and quantify the labeled cells. This method allows for quick and accurate measurement of CD4 cell count, making it an essential tool in the diagnosis and monitoring of HIV/AIDS. Hematology analyzers, chemilumination assays, and real-time PCR are not typically used for CD4 cell count measurement.

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  • 38. 

    58. ការធ្វើវិភាគរាប់កោសិកា​CD4 ប្រើវត្ថុវិភាគជាឈាមមិនកកដែលបូមដាក់ទីបដែលមានសារធាតុមិនអោយឈាមកកប្រភេទ: 

    • A.

      សារធាតុHeparin

    • B.

      សារធាតុSodium cytrat

    • C.

      សារធាតុEDTA

    • D.

      សារធាតុpostassium oxalate

    Correct Answer
    C. សារធាតុEDTA
    Explanation
    EDTA ជាសារធាតុដែលប្រើសម្រាប់ធ្វើវិភាគរាប់កោសិកាកែលម្អិតនៃវត្ថុវិភាគជាឈាម។ វាធ្វើឲ្យសារធាតុដែលមានប្រភេទកកិតគ្រប់ប្រភេទជាឈាមកកប្រភេទដែលកើតមានក្នុងវត្ថុវិភាគមិនអាចឈាមកកប្រភេទបាន។

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  • 39. 

    59. តើការរាប់មេរោគអេដស៏​(HIV Viral Load) សំរាប់តាមដានការព្យាបាលគេប្រើនូវបច្ចេកទេសអ្វី?

    • A.

      PCR Qualitative

    • B.

      PCR Quantitative

    • C.

      Chemiluminescent assay

    • D.

      Fluorescence –activated

    Correct Answer
    B. PCR Quantitative
    Explanation
    PCR Quantitative is used to measure the amount of HIV viral load in a person's blood. This test detects and quantifies the genetic material (RNA) of the virus in the blood sample. It is a highly sensitive and specific test that can provide important information about the level of viral replication and the effectiveness of antiretroviral therapy. This information helps healthcare providers monitor the progression of the disease and make informed decisions regarding treatment options.

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  • 40. 

    60. លក្ខណះខាងក្រោមនេះជានិយមន័យនៃagglutination ផ្ទាល់: ( the following is charateristic of the definition off direct agglutiation )

    • A.

      Ag ដែលមាននៅលើ Red Cells ស្រោបហើយប្រតិកម្មនឺងAb

    • B.

      ត្រូវការAgភ្ជាប់ទៅនឹងLatex particle

    • C.

      ប្រើAbភ្ជាប់ទៅនឹងgalactine particle

    • D.

      ប្រើAg ជាពិសេសភ្ជាប់ទៅនឹងគ្រាប់ឈាមក្រហម

    Correct Answer
    A. Ag ដែលមាននៅលើ Red Cells ស្រោបហើយប្រតិកម្មនឺងAb
    Explanation
    The characteristic of direct agglutination is the presence of Ag (antigen) on Red Cells and the interaction with Ab (antibody). In this process, the Ag needs to be connected to a latex particle, while the Ab is connected to a galactine particle. Additionally, Ag can also be connected to various types of red blood cells.

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  • 41. 

    30. តើបច្ចេកទេសតេស្តមួយណាដែលជាទូទៅប្រើសំរាប់ធ្វើរោគវិនិច្ជ័យនៅដំណាក់កាលដំបូងនៃការឆ្លងមេរោគថ្លើម?(Which of the laboratory technique are commonly used fordiagnostic of hepatitis for early stage of infection?)

    • A.

      Fluorescent tests

    • B.

      Immunochromatographic tests

    • C.

      Molecular diagnostic (PCR)

    • D.

      Agglutination tests

    • E.

      Chemilumination assay

    Correct Answer
    C. Molecular diagnostic (PCR)
    Explanation
    Molecular diagnostic (PCR) is commonly used for the early stage diagnosis of hepatitis. PCR stands for Polymerase Chain Reaction, which is a technique used to amplify and detect specific DNA sequences. In the case of hepatitis, PCR can detect the presence of viral DNA or RNA in the blood, even at very low levels. This makes PCR a highly sensitive and specific method for early detection of hepatitis infections. Other techniques like fluorescent tests, immunochromatographic tests, agglutination tests, and chemilumination assays may also be used for hepatitis diagnosis, but PCR is specifically mentioned as the commonly used technique for early stage detection.

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  • 42. 

    31. តើមេរោគរលាកថ្លើមមួយណាដែលមានVacinneសំរាប់បង្ការ? (Which of the following areavailable vaccin for hepatitis virus?)

    • A.

      Hepatitis B virus (HBV)

    • B.

      Hepatitis C virus (HCV)

    • C.

      Hepatitis D virus (HDV)

    • D.

      Hepatitis E virus (HEV)

    Correct Answer
    A. Hepatitis B virus (HBV)
    Explanation
    Hepatitis B virus (HBV) is a vaccine-preventable viral infection that affects the liver. It is transmitted through contact with the blood or other body fluids of an infected person. The HBV vaccine is highly effective in preventing infection and has been available since the 1980s. It is recommended for all infants, as well as for adults at risk of infection. Hepatitis C virus (HCV), Hepatitis D virus (HDV), and Hepatitis E virus (HEV) do not currently have vaccines available for prevention.

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  • 43. 

    32. តើមួយណាខាងក្រោមប្រើសំរាប់បង្ការការចំលងនៅក្រោយពេលប្រឈមនឹងការឆ្លងHBV? (Which of the following is used for preventing after exposed to HBV infection?)

    • A.

      Hepatitis B vaccine

    • B.

      Hepatitis B Antibody

    • C.

      Antiviral drug

    • D.

      Vaccine និង Antibody

    Correct Answer
    B. Hepatitis B Antibody
    Explanation
    Hepatitis B Antibody is used for preventing after exposed to HBV infection. This is because the hepatitis B antibody, also known as hepatitis B immunoglobulin (HBIG), is a concentrated form of antibodies that can provide immediate protection against the hepatitis B virus (HBV) after exposure. It is given to individuals who have been exposed to HBV through activities such as needlestick injuries, sexual contact with an infected person, or contact with contaminated blood or body fluids. The antibody helps to neutralize the virus and prevent it from causing an infection.

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  • 44. 

    33. ខាងក្រោមនេះជាប្រយោគដែលត្រឹមត្រូវសំរាប់HBc marker លើកលែងតែ(The followingare the property of HBc marker, Except:

    • A.

      Antigen not measurable

    • B.

      Recent infection IgM HBc-Ab

    • C.

      Test in dornor blood

    • D.

      Identify new HBV infection

    Correct Answer
    C. Test in dornor blood
    Explanation
    The correct answer is "Test in donor blood". The other options are all properties of the HBc marker. The HBc marker can be used to identify new HBV infection, detect recent infection using IgM HBc-Ab, and the antigen can be measured. However, testing in donor blood is not a property of the HBc marker.

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  • 45. 

    34 . លក្ខណះនៃការបង្ករជំងឺស្វាយដោយមេរោគTreponema Palidum ទាំងអស់លើកលែងតែ(Characteristics of the causative agent of syphilis, Treponema Pallidum, includesall EXCEPT :)

    • A.

      ជាគ្រួសាររបស់Spirochaetaceae

    • B.

      មិនមានកន្លែងស្នាក់ធម្មជាតិនៅក្នុងបរិយាកាស(Has no natural reservoir in theenvironment)

    • C.

      បង្ករកំណើតនៅនឹងម្ចាស់(Multiplies within the living host)

    • D.

      មិនមានPhospholipidsនៅនឹងសំបកក្រៅ( no phospholipids in its outer membrane)

    Correct Answer
    D. មិនមានPhospholipidsនៅនឹងសំបកក្រៅ( no phospholipids in its outer membrane)
    Explanation
    The correct answer is that Treponema Pallidum does not have phospholipids in its outer membrane. Phospholipids are a major component of the cell membrane in most bacteria, but Treponema Pallidum lacks them. This characteristic makes it unique compared to other bacteria.

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  • 46. 

    35. លទ្ធផលវិជ្ជមានខុសនៃតេស្តNon-Treponemalសំរាបើមេរោគស្វាយ តើបណ្ដាលមកពីអ្វី? (False-positive non-treponemal tests for syphilis may be due to which of thefollowing?)

    • A.

      Systemic lupus

    • B.

      Pregnancy

    • C.

      Infectious mononucleosis

    • D.

      Pregrancy; SLE; Infectious monoclonal

    Correct Answer
    D. Pregrancy; SLE; Infectious monoclonal
    Explanation
    False-positive non-treponemal tests for syphilis may be due to pregnancy, systemic lupus erythematosus (SLE), and infectious mononucleosis. This means that individuals who are pregnant, have SLE, or have infectious mononucleosis may test positive for syphilis even if they do not actually have the infection. These conditions can cause antibodies to be produced that cross-react with the antigens used in the non-treponemal tests, leading to a false-positive result.

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  • 47. 

    36. វិធីសាស្ត្រទីមួយនៃការចំលងមេរោគស្វាយ(T.Pallidum)គឺ(The primary mode oftransmission of T.Pallidum is):

    • A.

      តាមការប្រលាក់ទៅនឹងម្ជុល(Through contaminated needles)

    • B.

      តាមការរួមភេទ(Sexual transmission)

    • C.

      ប៉ះទៅនឹងឈាម(With blood contact)

    • D.

      មិនប៉ះផ្ទាល់(Indirect contact)

    Correct Answer
    B. តាមការរួមភេទ(Sexual transmission)
  • 48. 

    37. តើខាងក្រោមនេះមួយណាជាតេស្តដែលមិនមានលក្ខណះជាក់លាក់ទៅនឹងមេរោគស្វាយ?

    • A.

      RPR និង TPPA

    • B.

      TPPA និង TPHA

    • C.

      VDRL និង RPR

    • D.

      TPHA និង VDRL

    Correct Answer
    C. VDRL និង RPR
    Explanation
    The correct answer is VDRL and RPR. This is because VDRL (Venereal Disease Research Laboratory) and RPR (Rapid Plasma Reagin) are both blood tests used to detect syphilis, a sexually transmitted infection. They are screening tests that look for antibodies produced by the body in response to the infection. TPHA (Treponema pallidum hemagglutination assay) is another blood test used to confirm a positive result from VDRL or RPR. TPPA (Treponema pallidum particle agglutination assay) is also a confirmatory test for syphilis. Therefore, the combination of VDRL and RPR is the correct answer as they are both screening tests for syphilis.

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  • 49. 

    38. តើតេស្តមួយណាដែលប្រើសំរាប់វិភាគទឹកស្រោមខួរ(CSF) រកជំងឺNeurosyphilis? (Whichtest is recommended for testing cerebrospinal fluid for detection of neurosyphilis?)

    • A.

      RPR

    • B.

      VDRL

    • C.

      FTA-ABS

    • D.

      TPHA

    Correct Answer
    B. VDRL
    Explanation
    The correct answer is VDRL. VDRL (Venereal Disease Research Laboratory) is a test used to detect the presence of antibodies against the bacteria that causes syphilis in the cerebrospinal fluid. Neurosyphilis is a form of syphilis that affects the nervous system, and testing the cerebrospinal fluid is necessary for its diagnosis. The VDRL test is commonly used for this purpose as it is sensitive and specific in detecting neurosyphilis. RPR (Rapid Plasma Reagin), FTA-ABS (Fluorescent Treponemal Antibody Absorption), and TPHA (Treponema pallidum Hemagglutination Assay) are other tests used for syphilis diagnosis, but they are not specifically recommended for testing cerebrospinal fluid.

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  • 50. 

    39. តើមួយណាខាងក្រោមត្រឹមត្រូវសំរាប់Reagin? (Which of the following is true of reagin?)

    • A.

      វាអាចរកឃើញគ្រប់អ្នកជំងឺនៅដំណាក់កាលទីមួយនៃជំងឺស្វាយ

    • B.

      រកAbប្រឆាំងផ្ទាល់ទៅនឹងកំទេចកំទីកោសិកាខូចដោយសារមេរោគស្វាយ

    • C.

      Reagent Testsនៅវិជ្ជមានបន្ទាប់ពីព្យាបាលបានជោគជ័យក្រោយមួយឆ្នាំ

    • D.

      វារកឃើញនៅលើតែអ្នកជំងឺស្វាយប៉ុណ្ណោះ

    Correct Answer
    B. រកAbប្រឆាំងផ្ទាល់ទៅនឹងកំទេចកំទីកោសិកាខូចដោយសារមេរោគស្វាយ
    Explanation
    Reagin is a type of antibody that is produced in response to the presence of syphilis bacteria in the body. It is used in reagent tests to detect the presence of syphilis antibodies in a person's blood. This answer states that reagin can be found in individuals with active syphilis infection, as it reacts with the specific antigen produced by the syphilis bacteria.

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    Quiz Edited by
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