Laboratory Measurement Of Prolactin

The statement is true because the prolactin-PEG result needs to be multiplied by 2 in order to obtain the final concentration. This suggests that there is a specific conversion factor or adjustment that needs to be applied to the initial result in order to accurately determine the final concentration of prolactin-PEG.

Monomeric prolactin is the biologically active form of prolactin variant. This suggests that the monomeric form of prolactin is responsible for the physiological functions of prolactin in the body. The other variants, big prolactin and big-big prolactin, may have different molecular structures or modifications that render them inactive or less active in terms of their biological effects.

Anti-diuretic hormone (ADH) is released from the posterior pituitary in response to dehydration. The loss of water from body fluids increases their salt concentration, which stimulates the hypothalamic neurons to release ADH. ADH signals the kidneys to conserve water.

Prolactin is mainly secreted by the anterior pituitary gland.

The posterior half of the pituitary gland is of neural origin and is an extension of the brain. This means that it is derived from the same embryonic tissue as the brain and is connected to it. The posterior pituitary gland is responsible for storing and releasing hormones that are produced in the hypothalamus of the brain. These hormones include oxytocin and antidiuretic hormone (ADH), which play important roles in regulating various bodily functions.

There are three major variants of circulating prolactin.

Hyperprolactinemia is a condition characterized by high levels of prolactin hormone in the blood. This hormone is responsible for milk production in females. Symptoms of hyperprolactinemia in females typically include anovulation (lack of ovulation), irregular periods, and amenorrhea (absence of menstruation). However, fever is not a symptom associated with hyperprolactinemia. Fever is usually caused by an infection or inflammation in the body and is not directly related to hormonal imbalances. Therefore, fever is not a symptom of hyperprolactinemia in females.

The gel filtration result shows that the sample consists mainly of monomeric prolactin. This means that the prolactin molecules in the sample are mostly in their individual, single-unit form rather than being aggregated or bound together. This information is important in understanding the structure and composition of the prolactin sample being tested.

The correct answer is "Mixed equal volume of (25% w/v) PEG with serum. Centrifuged the mixture at 14000 rcf for 10 mins." This protocol is used for prolactin PEG screening because it specifies the correct concentration of PEG (25% w/v) and the correct centrifugation conditions (14000 rcf for 10 mins). This protocol ensures that the PEG and serum are mixed in equal volumes and that the mixture is properly centrifuged to separate the prolactin.

Prolactin is a hormone primarily responsible for stimulating breast development and milk production in females. It also plays a role in maintaining the corpus luteum during pregnancy, which is important for supporting the pregnancy. Additionally, prolactin is involved in testicular function in males. However, it does not stimulate the ovary by promoting FSH and LH production. FSH (follicle-stimulating hormone) and LH (luteinizing hormone) are primarily regulated by other hormones such as gonadotropin-releasing hormone (GnRH).

Reflex test will only be done for all initially tested high cases.

Primary hyperthyroidism is not a common cause of hyperprolactinemia. Hyperthyroidism is associated with increased levels of thyroid hormones, which can lead to symptoms such as weight loss, increased heart rate, and tremors. However, it does not typically cause an increase in prolactin levels. The other options listed, including benign pituitary tumor (prolactinoma), dopamine antagonist drugs, and primary hypothyroidism, are all known causes of hyperprolactinemia.

Adrenocorticotropic hormone (ACTH) is a hormone released by cells of the anterior pituitary into the general circulation of the body.