Human A&p 2 - Endocrine System

Gonadotrophins are hormones that stimulate the gonads (ovaries in females and testes in males). LH (luteinizing hormone) and FSH (follicle-stimulating hormone) are both types of gonadotrophins. LH is responsible for triggering ovulation and the production of testosterone in males, while FSH stimulates the growth and development of follicles in females and sperm production in males. Therefore, the combination of LH and FSH is required for the production of gonadotrophins.

TSH stands for thyroid stimulating hormone. This hormone is produced by the pituitary gland and plays a crucial role in regulating the production and release of thyroid hormones by the thyroid gland. TSH stimulates the growth and function of the thyroid gland, ensuring that it produces an adequate amount of thyroid hormones to maintain overall metabolic balance in the body.

The pineal gland secretes melatonin. Melatonin is a hormone that regulates sleep-wake cycles and is involved in the body's internal clock. The pineal gland is located in the brain and is responsible for producing and releasing melatonin in response to darkness. Melatonin levels increase at night, signaling to the body that it is time to sleep, and decrease during the day, promoting wakefulness.

The thyroid gland is located in the anterior trachea just below the larynx. It is responsible for producing hormones that regulate metabolism, growth, and development in the body. The placement of the thyroid gland in this specific location allows it to have direct access to the trachea and larynx, enabling it to efficiently release its hormones into the bloodstream for distribution throughout the body.

The correct answer is "Infundibulum." The pituitary gland is connected to the hypothalamus through a stalk-like structure called the infundibulum. The infundibulum acts as a bridge between the two structures, allowing for communication and the transfer of hormones.

Gonadocorticoids include sex hormones, primarily androgens such as testosterone. While the amounts produced by the gonads are more significant, gonadocorticoids may still play a role in the onset of puberty. In women, they may also be involved in sex drive.

The anterior pituitary is a gland located in the brain that is responsible for releasing hormones into the bloodstream. These hormones play a crucial role in regulating various bodily functions such as growth, metabolism, and reproduction. Therefore, the correct answer is "releases hormones."

The adrenal medulla is responsible for secreting epinephrine and norepinephrine into the blood. It is a sympathetic nervous tissue that is activated by sudden stress and produces the fight-or-flight response.

The correct answer is Hypophysis. The Pituitary Gland is commonly known as the Hypophysis. It is a small gland located at the base of the brain and is often referred to as the "master gland" because it plays a crucial role in regulating various bodily functions. The Pituitary Gland produces and releases hormones that control the activities of other endocrine glands in the body, influencing growth, metabolism, reproduction, and many other essential processes.

The thymus is an organ that is large in infants and children and shrinks with age. As it shrinks, it is replaced by adipose (fat) tissue and connective tissue. The thymus is involved in producing T cells, which are a type of white blood cell that plays a key role in the immune system. Therefore, the correct answer is Thymus.

Mineralocorticoids are a type of corticosteroids that regulate electrolyte concentrations, especially sodium and potassium. They are produced in the adrenal cortex and play a crucial role in maintaining the balance of these electrolytes in the body. Sodium and potassium are essential for various bodily functions, including nerve and muscle function, fluid balance, and blood pressure regulation. Mineralocorticoids help in reabsorbing sodium and excreting potassium in the kidneys, thus controlling their levels in the body. This regulation is vital for maintaining overall health and proper functioning of the body's systems.

Cortisol, cortisone, and corticosterone are all types of glucocorticoids. Glucocorticoids are a group of steroid hormones that are produced by the adrenal glands. They play a crucial role in regulating various processes in the body, including metabolism, immune response, and stress response. Cortisol, in particular, is often referred to as the "stress hormone" because it is released in response to stress and helps the body cope with it. Therefore, glucocorticoids, including cortisol, cortisone, and corticosterone, are the most important hormones in this group.

Insulin-Dependent diabetes Mellitus, also known as Type 1 Diabetes, is the correct answer because it matches the given information. Type 1 Diabetes accounts for 3% of people with diabetes Mellitus, is characterized by decreased insulin secretion, develops from an autoimmune destruction of pancreatic islets, and most commonly develops in young people. The therapy for Type 1 Diabetes is insulin injections.

Calcitonin is a hormone produced by the parafollicular cells of the thyroid gland. It helps to regulate calcium levels in the body by inhibiting the activity of osteoclasts, which are responsible for breaking down bone tissue. This hormone plays a crucial role in maintaining bone health and preventing excessive calcium release into the bloodstream.

GH stands for Growth Hormone and is produced by the Anterior Pituitary gland. Its major target is Bones and Skeletal Muscle. GH is a nontrophic hormone, meaning it does not directly stimulate growth in its target tissues but instead promotes the secretion of insulin-like growth factors (IGFs) which are responsible for growth.

Insufficient insulin is a characteristic feature of diabetes mellitus, a chronic metabolic disorder. Diabetes mellitus is caused by the body's inability to produce enough insulin or effectively use the insulin it produces. Insulin is a hormone that regulates blood sugar levels, and when there is insufficient insulin, blood sugar levels become elevated, leading to various symptoms and complications associated with diabetes mellitus. Diabetes insipidus, on the other hand, is a different condition characterized by excessive thirst and urination due to a problem with the hormone vasopressin, not insulin.

Excess cortisol, which is a hormone produced by the adrenal glands, leads to Cushing's Disease. This condition occurs when there is an overproduction of cortisol in the body. Symptoms of Cushing's Disease include weight gain, particularly in the face, neck, and upper body, thinning skin, easy bruising, high blood pressure, and muscle weakness. It can also cause mood swings, irritability, and depression. Treatment options for Cushing's Disease may include medication, surgery, or radiation therapy to reduce cortisol levels and alleviate symptoms.

The correct answer is Zona Reticularis, Zona Glomerulosa, Zona Fasiculata. The adrenal cortex is composed of three distinct layers: the Zona Glomerulosa, which produces mineralocorticoids such as aldosterone; the Zona Fasiculata, which produces glucocorticoids such as cortisol; and the Zona Reticularis, which produces androgens. These three layers work together to regulate various physiological processes in the body.

ADH (antidiuretic hormone) deficiency can lead to diabetes insipidus, a condition characterized by excessive thirst and urination. ADH is responsible for regulating the body's water balance by controlling the amount of water reabsorbed by the kidneys. When there is a deficiency of ADH, the kidneys are unable to properly reabsorb water, leading to the production of large volumes of dilute urine and increased thirst. This condition is known as diabetes insipidus, which is different from diabetes mellitus (type 1 and type 2 diabetes). Therefore, the given statement is true.

Adrenocorticotrophic Hormone (ACTH) stimulates the adrenal cortex to release corticosteroid hormones. ACTH is a hormone produced by the pituitary gland that acts on the adrenal cortex to promote the synthesis and release of corticosteroid hormones, such as cortisol. These hormones play important roles in regulating metabolism, immune function, and stress response in the body.

Glucagon is a hormone produced by the pancreas that stimulates the release of glucose into the blood. It mainly targets the liver and signals it to break down stored glucose, also known as glycogen. This process helps to increase blood sugar levels when they are low, ensuring that the body has a steady supply of energy.

Parafollicular cells in the thyroid produce calcitonin. Calcitonin is a hormone that helps regulate calcium levels in the body. It works by inhibiting the activity of osteoclasts, which are cells responsible for breaking down bone tissue and releasing calcium into the bloodstream. By reducing the activity of osteoclasts, calcitonin helps to lower blood calcium levels. This hormone is produced and released by the parafollicular cells, also known as C cells, which are located in the thyroid gland.

The pancreas is both endocrine and exocrine tissue because it functions as an endocrine gland by producing and releasing hormones such as insulin and glucagon into the bloodstream to regulate blood sugar levels. It also acts as an exocrine gland by secreting digestive enzymes into the small intestine to aid in the digestion and absorption of nutrients.

TH refers to thyroid hormone, which is the body's major metabolic hormone. It is produced by the thyroid gland and affects almost every cell in the body. Thyroid hormone plays a crucial role in regulating metabolism, growth, and development. It helps to control the rate at which the body uses energy, influences protein synthesis, and affects the function of various organs and tissues. Therefore, TH is the correct answer in this context.

PTH (parathyroid hormone) and calcitonin are two hormones that regulate calcium levels in the body. While PTH increases blood calcium levels by stimulating the release of calcium from bones and increasing calcium absorption in the intestines, calcitonin does the opposite. Calcitonin decreases blood calcium levels by inhibiting bone breakdown and increasing calcium excretion by the kidneys. Therefore, PTH and calcitonin have opposing effects on calcium regulation in the body.

Noninsulin-Dependent Diabetes Mellitus, also known as Type 2 Diabetes, is the correct answer because it accounts for 97% of people with Diabetes Mellitus. This type of diabetes is characterized by the inability of tissues to respond to insulin. Additionally, it is suggested that leptin may play a role in the development of Type 2 Diabetes, and in some cases, abnormal receptors may be produced or antibodies may bind to receptors and deactivate them.

Down regulation refers to the decrease in the number of receptors on a target cell. This process occurs in response to a prolonged exposure to a high concentration of a signaling molecule. The decrease in receptors reduces the cell's sensitivity to the signaling molecule, resulting in a decreased cellular response. Down regulation is an important regulatory mechanism that helps maintain homeostasis and prevent overstimulation of cells.

Up regulation refers to the increase in the number of receptors on a target cell. This process occurs in response to a decrease in the concentration of a signaling molecule or hormone in the body. By increasing the number of receptors, the target cell becomes more sensitive to the signaling molecule, allowing for a stronger response. Up regulation is a regulatory mechanism that helps maintain homeostasis in the body.

The anterior pituitary is a glandular organ located at the base of the brain, and it is not directly connected to the hypothalamus through neural connections. Instead, the hypothalamus controls the anterior pituitary through a hormonal pathway. The hypothalamus releases hormones into the bloodstream, which then travel to the anterior pituitary and stimulate or inhibit the release of hormones from the pituitary gland. Therefore, the statement that the anterior pituitary has no neural connection to the hypothalamus is true.

Aldosterone is the most important and abundant mineralocorticoid. It is produced by the adrenal glands and plays a crucial role in regulating the body's electrolyte balance, particularly by promoting the reabsorption of sodium and the excretion of potassium in the kidneys. This hormone helps to maintain blood pressure, fluid balance, and overall homeostasis in the body.

The thyroid gland is the largest pure endocrine gland in the body. It is responsible for producing and releasing thyroid hormones, which regulate metabolism and energy levels in the body. The adrenal gland, pituitary gland, pineal gland, and parathyroid gland also produce hormones, but they are either smaller in size or have additional functions beyond purely endocrine functions. Therefore, the correct answer is the thyroid gland.

Cushing's Disease is the correct answer because it is a condition caused by prolonged exposure to high levels of cortisol, a hormone produced by the adrenal glands. This excess cortisol can lead to muscle and bone loss, water and salt retention, hypertension (edema/moon face), redistribution of fat to the posterior neck, and increased susceptibility to severe infections. Addison's Disease, Graves Disease, and Myxedema are not associated with these specific symptoms.

When blood becomes too concentrated, the hormone ADH (antidiuretic hormone) is released. ADH acts on the kidney tubules, causing them to reabsorb water from the urine back into the bloodstream. This process helps to dilute the blood and maintain its normal concentration. As a result, less urine is produced and the body retains more water.

The kidneys are responsible for producing erythropoietin (EPO), which is a hormone that signals the bone marrow to increase the production of red blood cells. Red blood cells are important for carrying oxygen throughout the body. Therefore, the kidneys play a crucial role in maintaining the body's oxygen levels by producing EPO and regulating red blood cell production.

Graves Disease is the correct answer because it is an autoimmune disease where abnormal antibodies mimic thyroid-stimulating hormone (TSH), leading to an overproduction of thyroid hormones. This results in high levels of blood thyroid hormone (TH), causing symptoms such as weight loss, rapid heartbeat, and bulging eyes. Paget's Disease is a bone disorder, myxedema is a severe form of hypothyroidism, and cretinism is a congenital form of hypothyroidism, none of which involve high TH levels.

Cortisol's primary effects include gluconeogenesis, the breakdown of proteins and reuse of amino acids for repair, working with adrenaline to increase blood pressure for rapid delivery of fuel and nutrients to cells, and preventing over-activity of the immune system. During periods of stress, blood levels of glucose, fatty acids, and amino acids dramatically rise.

Adipose tissue is responsible for releasing leptin into the body. Leptin is a hormone that regulates energy balance by suppressing appetite and signaling satiety to the central nervous system (CNS). This means that when adipose tissue releases leptin, it sends signals to the CNS that the body is full and does not need to eat anymore. Therefore, the correct answer is Adipose.

Addison's Disease can occur due to a lack of either Aldosterone or Cortisol. This condition is characterized by the adrenal glands not producing enough of these hormones. Aldosterone helps regulate blood pressure and electrolyte balance, while Cortisol is involved in managing stress response and metabolism. When there is a deficiency in either of these hormones, it can lead to symptoms such as fatigue, weight loss, low blood pressure, and electrolyte imbalances. Therefore, Addison's Disease is the correct answer as it fits the description of a condition caused by a lack of Aldosterone or Cortisol.

Gluconeogenesis is the process in which glucose is synthesized from non-carbohydrate sources such as amino acids, glycerol, and lactate. This process occurs mainly in the liver and kidneys when the body needs glucose for energy but there is a limited supply of carbohydrates available. Glycogen is a storage form of glucose in the body, glucagon is a hormone that increases blood sugar levels, and insulin is a hormone that lowers blood sugar levels. Therefore, the correct answer is gluconeogenesis, as it specifically refers to the production of glucose from molecules other than starch and sugar.

The adrenal glands consist of two parts: the adrenal cortex and the adrenal medulla. The adrenal cortex is the outer layer of the gland and is responsible for producing hormones such as cortisol and aldosterone. The adrenal medulla, on the other hand, is the inner part of the gland and is involved in the production of adrenaline and noradrenaline, which are responsible for the body's response to stress and emergencies.

This answer suggests that a trophic hormone is responsible for instructing the body on how to produce the final hormone. In other words, it acts as a signal or guide for the body to synthesize and release the final hormone.

The hypothalamus is known as the neuroendocrine gland because it plays a crucial role in regulating both the nervous system and the endocrine system. It produces and releases various hormones that control the release of hormones from the pituitary gland, which in turn regulates many other glands in the body. The hypothalamus also helps maintain homeostasis by controlling body temperature, hunger, thirst, and sleep. Therefore, it is the correct answer for the neuroendocrine gland.

Aldosterone pumps sodium out of kidney tubules and into the blood while it pumps potassium out of blood and into the kidney tubules. This process helps regulate the balance of these ions in the body and plays a crucial role in maintaining proper fluid and electrolyte balance.

Calcitonin is a hormone that helps regulate calcium levels in the body. It inhibits bone breakdown by decreasing the activity of osteoclasts, the cells responsible for bone resorption. Paget's disease is a condition characterized by abnormal bone remodeling, leading to weakened and deformed bones. Calcitonin can be used as a treatment for Paget's disease to help slow down the excessive bone turnover and reduce bone pain. It is not commonly used for the other conditions listed, such as myxedema (severe hypothyroidism), Graves Disease (hyperthyroidism), or cretinism (congenital hypothyroidism).