Hmp Shunt - High Yield Topic Series
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HMP shunt is significant in cellular metabolism because it produces
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NADH
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NADPH
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Acetyl CoA
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ATP
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Explore the HMP shunt through this High Yield Topic Series quiz. Assess your understanding of the pentose phosphate pathway, its energy yield, significance in producing NADPH, and the metabolic activities in various tissues. This quiz is essential for students and professionals in biochemistry and medical fields.
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- 2.
Net Energy yield from pentose phosphate pathway is
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+2 ATP
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0 ATP
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+4 ATP
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-2 ATP
Correct Answer
A. 0 ATPExplanation
The correct answer is 0 ATP. The pentose phosphate pathway is an alternative pathway to glycolysis for the breakdown of glucose. It primarily functions to generate NADPH and ribose-5-phosphate for nucleotide synthesis. While it does produce some ATP, the net energy yield from the pentose phosphate pathway is 0 ATP. This is because the ATP consumed in the initial steps of the pathway is later regenerated in subsequent steps, resulting in no net gain or loss of ATP.Rate this question:
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- 3.
HMP shunt is active in all of the following EXCEPT
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RBC, liver & adipose tissue
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Adrenal cortex & Thyroid
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Testis & lactating mammary gland
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Skeletal muscle
Correct Answer
A. Skeletal muscleExplanation
The HMP (hexose monophosphate) shunt is a metabolic pathway that occurs in various tissues and is responsible for the production of NADPH, which is important for cellular processes such as lipid synthesis and antioxidant defense. The HMP shunt is active in RBCs, liver, adipose tissue, adrenal cortex, thyroid, testis, and lactating mammary gland. However, it is not active in skeletal muscle. This is because skeletal muscle primarily relies on glycolysis for energy production and does not require the NADPH produced by the HMP shunt.Rate this question:
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- 4.
NADpH is produced only by HMP shunt
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True
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False
Correct Answer
A. FalseExplanation
cytoplasmic isocitrate dehydrogenase and malic enzyme can also produce NADPH.Rate this question:
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- 5.
Which is NOT true about the 2 phases of HMP shunt
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Oxidative Phase Generates NADPH
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Oxidative Phase is irreversible
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Nonoxidative Phase Generates Ribose Precursors
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NAD+ is the proton acceptor in oxidative phase
Correct Answer
A. NAD+ is the proton acceptor in oxidative phaseExplanation
NADP+ is the proton acceptorRate this question:
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- 6.
Transketolase reaction requires
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Mg2+
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Thiamin diphosphate
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Both
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None
Correct Answer
A. BothExplanation
The correct answer is "Both". The transketolase reaction requires both Mg2+ and thiamin diphosphate. Mg2+ acts as a cofactor for the enzyme, helping to stabilize the reaction intermediates. Thiamin diphosphate, also known as vitamin B1, is a coenzyme that plays a crucial role in the transfer of two-carbon units during the reaction. Without either of these components, the transketolase reaction would not be able to proceed efficiently.Rate this question:
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Current Version
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Mar 22, 2023Quiz Edited by
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Jun 02, 2012Quiz Created by
Kar
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