Biochem Hemoglobin

20 Questions | Total Attempts: 3866

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Biochem Hemoglobin

Biochem quiz about hemoglobin and immunoglobin. 20 questions.


Questions and Answers
  • 1. 
    What contains 2 alpha chains and 2 beta chains that assume a quarternary higher order conformation?
    • A. 

      Maternal hemoglobin

    • B. 

      Myoglobin

    • C. 

      Immunoglobin

    • D. 

      Fetal hemoglobin

  • 2. 
    Which of the following is in red muscle and consists of a single polypeptide with a prosthetic heme group?
    • A. 

      Materal hemoglobin

    • B. 

      Myoglobin

    • C. 

      Immunoglobin

    • D. 

      Fetal hemoglobin

  • 3. 
    If iron in hemoglobin is oxidized to 3+, what disease may occur?
    • A. 

      Sickle cell anemia

    • B. 

      Methemoglobinemia

    • C. 

      Carbon monoxide poisoning

    • D. 

      Cystic fibrosis

  • 4. 
    When binding with oxygen, what type of binding curve does myoglobin have?
    • A. 

      Linear

    • B. 

      Sigmoidal

    • C. 

      Hyperbolic

    • D. 

      It has none

  • 5. 
    When binding with oxygen, what type of binding curve does hemoglobin have?
    • A. 

      Linear

    • B. 

      Sigmoidal

    • C. 

      Hyperbolic

    • D. 

      It has none

  • 6. 
    When will hemoglobin have the highest affinity for oxygen?
    • A. 

      When ph is low

    • B. 

      When carbon monoxide levels are high

    • C. 

      At high elevations

    • D. 

      When 2,3-bisphosphoglycerate levels are low

  • 7. 
    What phenomenon occurs when decreased ph causes hemoglobin to release oxygen into tissues?
    • A. 

      Allosteric effect

    • B. 

      ELISA

    • C. 

      Bohr shift

    • D. 

      Western blotting

    • E. 

      B and D

  • 8. 
    What consists of 2 alpha chains and 2 gamma chains?
    • A. 

      Materal hemoglobin

    • B. 

      Myoglobin

    • C. 

      Immunoglobin

    • D. 

      Fetal hemoglobin

  • 9. 
    What has the highest affinity for oxygen?
    • A. 

      Materal hemoglobin without 2,3-bisphosphoglycerate

    • B. 

      Myoglobin

    • C. 

      Materal hemoglobin with 2,3-bisphosphoglycerate

    • D. 

      Fetal hemoglobin with 2,3- bisphosphoglycerate

  • 10. 
    What will happen at high elevations?
    • A. 

      2,3-bisphosphoglycerate concentration increases and hemoglobins affinity for oxygen decreases

    • B. 

      2,3-bisphosphoglycerate concentration decreases and hemoglobins affinity for oxygen decreases

    • C. 

      2,3-bisphosphoglycerate concentration decreases and hemoglobins affinity for oxygen decreases

    • D. 

      2,3-bisphosphoglycerate concentration increases and hemoglobins affinity for oxygen increases

  • 11. 
    A point mutation in the beta-globin gene changing the codon from glutamate to valine will likely cause what disease?
    • A. 

      Sickle cell anemia

    • B. 

      Methemoglobinemia

    • C. 

      Carbon monoxide posioning

    • D. 

      Cystic fibrosis

  • 12. 
    What produced by B lymphocytes and are responsible for humoral immunity?
    • A. 

      Materal hemoglobin

    • B. 

      Myoglobin

    • C. 

      Immunoglobin

    • D. 

      Fetal hemoglobin

  • 13. 
    Immunoglobin consists of what?
    • A. 

      2 heavy chains and 2 light chains

    • B. 

      2 heavy chains and 3 light chains

    • C. 

      3 heavy chains and 2 light chains

    • D. 

      3 heavy chains and 3 light chains

  • 14. 
    Chains of immunoglobin are held together by what?
    • A. 

      Hydrogen bonds

    • B. 

      Disulfide bonds

    • C. 

      Ionic bonds

    • D. 

      Van der waals interctions

  • 15. 
    What contains 3 hypervariable regions called complimentarity determining regions (CDRs)?
    • A. 

      Fab region

    • B. 

      Fc region

    • C. 

      Papain cleavage sites

    • D. 

      Variable domain

  • 16. 
    In what region do antigens bind to immunoglobin in an extremely specific manner?
    • A. 

      Fab region

    • B. 

      Fc region

    • C. 

      Papain cleavage sites

    • D. 

      Variable domain

  • 17. 
    The constant region of an immunoglobin is known as what?
    • A. 

      Fab region

    • B. 

      Fc region

    • C. 

      Papain cleavage sites

    • D. 

      Variable domain

  • 18. 
    What can be used to test for pregnancy, HIV and a patients cholesterol level?
    • A. 

      Allosteric effect

    • B. 

      ELISA

    • C. 

      Bohr shift

    • D. 

      Western blotting

    • E. 

      B and D

  • 19. 
    WHich of the following is true?
    • A. 

      Hemoglobin is involved in transporting oxygen

    • B. 

      Myoglobin is involved in oxygen storage

    • C. 

      Compared to oxygen, carbon monoxide has a higher affinity for hemoglobin

    • D. 

      A, B and C

    • E. 

      A and C

  • 20. 
    Which of the following is false?
    • A. 

      The binding curve of oxygen and hemoglobin is sigmiodal for a patient with carbon monoxide poisoning

    • B. 

      In the presence of 2,3-bisphosphoglycerate, the affinity for oxygen in fetal hemoglobin is unaffected

    • C. 

      Myoglobin does not use an allosteric effect

    • D. 

      The allosteric effect will increase the binding of oxygen to hemoglobin

    • E. 

      None of the above

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