Hemolytic Disease In The Newborn

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I affirm, by submitting this online test and evaluation, that I have read the material in this educational offering. � I verify that the personal information submitted is mine and for the purpose of obtaining continuing education credit. � Contact hours are offered for continuing education. �Therefore, they are valid only for the first time this activity is completed. �I affirm that this is the first time I have submitted the test and evaluation for credit for this activity. There are 25 questions on this test. A score of 85% is required to be successful; no more than 3 questions may be incorrect. Good Luck! Questions 26-36 are your evaluation of this learning activity. This evaluation must be completed to receive credit. Thank you.


Questions and Answers
  • 1. 
    _________________ is an immunoglobulin that provides protection against most common infections.  It is a glycoprotein that stimulates phagocytosis.
    • A. 

      Antigen

    • B. 

      Antibody

  • 2. 
    ________________ is an oligosaccharide and is a marker on the surface of cells that identifies the cell type.  The T- and B-Cells respond to these as part of the immune response.
    • A. 

      Antigen

    • B. 

      Antibody

  • 3. 
    The term autosome, or autosomal, refers to all of the chromosomes, including the sex, or X and Y, chromosomes.
    • A. 

      True

    • B. 

      False

  • 4. 
    A person's blood type is determined by the presence or absence of specific antigen(s) on the surface of their red blood cells (RBCs).
    • A. 

      True

    • B. 

      False

  • 5. 
    ______________ measures the effect of the infant's serum on unrelated adult RBCs.
    • A. 

      Indirect Coombs' test

    • B. 

      Direct Coombs' test

  • 6. 
    ______________ measures the amount of maternal antibody coating an infant's RBC.
    • A. 

      Indirect Coombs' test

    • B. 

      Direct Coombs' test

  • 7. 
    _________________ is a protein or starch that is commonly used as an intravascular volume expander.
    • A. 

      Crystalloid solution

    • B. 

      Colloid solution

  • 8. 
    The production of blood cells is known as -
    • A. 

      Hemolysis

    • B. 

      Hematopoiesis

    • C. 

      Hematoblast

  • 9. 
    The production of red blood cells is know as -
    • A. 

      Erythrocyte

    • B. 

      Erythroblast

    • C. 

      Erythropoiesis

  • 10. 
    By 24 weeks gestation, production of RBCs in the __________ surpasses that of the liver.
    • A. 

      Spleen

    • B. 

      Kidneys

    • C. 

      Bone marrow

    • D. 

      All of the above

  • 11. 
    RBCs are able to release oxygen into the systemic tissues because of higher oxygen tension in the systemic capillaries than in the surrounding tissues.
    • A. 

      True

    • B. 

      False

  • 12. 
    Hemolytic disease in the newborn results in a shortened life of the fetal and/or newborn RBCs because of the mother's sensitization to the fetal RBC antigens inherited from the father.
    • A. 

      True

    • B. 

      False

  • 13. 
    Sensitization of the mother's immune system to the fetus' RBCs stimulates the production of the immunoglobulin, _____ , that is transplacentally transferred to the fetus.
    • A. 

      IgA

    • B. 

      IgM

    • C. 

      IgG

    • D. 

      IgD

  • 14. 
    For the following question, please check all answer(s) that apply. From the maternal blood groups listed below, which infant(s) need testing at birth?
    • A. 

      O negative

    • B. 

      O positive

    • C. 

      AB negative

    • D. 

      B positive

  • 15. 
    For the following question, please check all answer(s) that apply. Nursing care of the infant receiving phototherapy includes -
    • A. 

      Increasing and/or changing feeding frequency, using glycerin suppositories

    • B. 

      Monitoring temperature every 30 minutes, monitoring blood glucose as needed

    • C. 

      Maintaining bank lights 12 inches above the infant with an intensity of at least 12

    • D. 

      Initiating IV therapy, turning phototherapy lights off during lab draws

  • 16. 
    For the following question, please check all answer(s) that apply. Nursing care during an exchange transfusion includes -
    • A. 

      Verifying parental consent and maintaining all emergency equipment nearby

    • B. 

      Monitoring vital signs every 10 minutes and blood glucose every 30 minutes during the procedure

    • C. 

      Constant 1:1 observation and recording blood volume in and out

  • 17. 
    For the following question, please check all answer(s) that apply. Considerations when administering intravenous immunoglobulin (IVIG) include -
    • A. 

      The solution is reconstituted by pharmacy, keep it refrigerated until it is used

    • B. 

      The solution foams easily and is compatible with all dextrose solutions

    • C. 

      Monitoring vital signs, glucose, and IV site every 30 minutes during the procedure

  • 18. 
    Rh incompatibility is also known as erythroblastosis fetalis.
    • A. 

      True

    • B. 

      False

  • 19. 
    Rh incompatibility occurs when Rh-negative maternal blood is exposed to Rh-positive fetal RBCs.
    • A. 

      True

    • B. 

      False

  • 20. 
    Recommended testing at birth includes -
    • Maternal cord blood for Rh and grouping, Coombs' test, and bilirubin
    • Infant blood for type and screen, direct Coombs' test, and bilirubin
    • A. 

      True

    • B. 

      False

  • 21. 
    Rho(D) immune globulin (RhoGAM®) is -
    • A. 

      Immunoglobulin M

    • B. 

      Immunoglobulin A

    • C. 

      Immunoglobulin G

    • D. 

      None of the above

  • 22. 
    With the widespread use of Rho(D) immune globulin , non-immune mechanisms are the major causes of hydrops fetalis.
    • A. 

      True

    • B. 

      False

  • 23. 
    For the following question, please check all answer(s) that apply. Infants with hydrops fetalis may present with -
    • A. 

      Pericardial and/or pleural effusions

    • B. 

      Ascites and/or enlarged liver and spleen

    • C. 

      Respiratory distress and/or hypotension

    • D. 

      Anemia and/or hypoalbuminemia

  • 24. 
    Each blood group (A, B, AB, O) has an antigen on the surface of the RBC and the corresponding antibody to the antigen that is missing in the plasma.
    • A. 

      True

    • B. 

      False

  • 25. 
    ABO incompatibility is more common than Rh incompatibility, is less severe, can result in RBC hemolysis, and can occur during the first pregnancy.
    • A. 

      True

    • B. 

      False

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