Diabetes Quiz: How Well You Really Know?

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2. In the beta cell, increased intracellular potassium ____________ the cell and opens a voltage-gated calcium channel.

Depolarizes

Hyperpolarizes

3. In a lazy person, more glucose is going into glycogen storage.

True

False

4. Glut4 is always expressed.

True

False

5. The net effect of amylin is to...

Slow the influx of exogenous glucose into the blood

Slow the influx of endogenous glucose into the blood

Slow both the influx of endogenous and exogenous glucose into the blood

6. Glucagon activates phosphorylase to stimulate glycogenolysis.

True

False

7. LJ's wife comes into your pharmacy. She is a 40-year-old caucasian female coffee drinker with high triglycerides but no family history. She is wondering if the ADA recommends that she be screened for diabetes? She has never been screened before. You tell her...

Yes, be screened

No, do not be screened

8. Insulin in the portal vein, _________ gluconeogenesis in the liver.

Decreases

Increases

9. Epinephrine may also increase glycogenolysis and gluconeogenesis.

True

False

10. Glut 2 is a non-inducible glucose transporter?

True

False

11. Nephrogenic DI and genetic DI are deficiencies in AVP ________

Secretion

Action

12. How much glucose should you take (to try to get your blood sugar up) before you call the hospital?

15 grams

30 grams

45 grams

60 grams

13. The muscles lack of G6P phosphatase ensures oxidation?

True

False

14. Normal urine output is between _____ mL/kg/day.

2 to 6

6 to 12

12 to 24

24 to 48

Greater than 50

15. Amylin

Slows the influx of glucose into the blood

Increases gastric emptying

Increases postprandial glucose secretion

Opposes the action of insulin

Helps match glucose concentration with the rate of insulin-induced glucose clearance

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16. Hexokinase II has a high Km.

True

False

17. Glucagon stimulates acetyl Co-A carboxylase.

True

False

18. In type 2 diabetics, GIP and GLP-1 secretion are usually reduced.

True

False

19. DKA is generally seen in...

Type II diabetics and young adults

Type I diabetics and African Americans

Type II diabetics and African Americans

Type I diabetics and young adults

20. Insulin secretion from the beta-cell involves what?

ATP sensitive Ca channel

Glut2

Hexokinase

Depolarization

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21. GLP-1

Enhances satiety

Slows gastric emptying

Suppresses glucagon in a glucose-independent manner

Suppresses glucagon in a glucose-dependent manner

Improves insulin sensivity

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22. What drugs can cause secondary diabetes mellitus?

Lithium

Beta blockers

Cisplatin

Diuretics

Glucocorticoids

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23. GLP-1

Stimulates insulin-dependent glucose secretion

Suppresses insulin secretion

Suppresses glucagon secretion

Promotes b-cell neogenesis in animal models

Increases gastric emptying

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24. The diagnostic triad of DKA involves

Fruity breath

Hyperglycemia (600+)

Hyperglycemia (250+)

Acidosis

Low ketone levels

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25. Insulin

Increases proteolysis

Increases triglyceride formation

Blocks synthesis and release of glucagon

Increases glycogenesis

Inhibits glucose oxidation in the muscle

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Diabetes Quiz: How Well You Really Know?

1. The main physiologic stimulus for AVP secretion is plasma _________.

2.

What first name or nickname would you like us to use?

2. In the beta cell, increased intracellular potassium ____________ the cell and opens a voltage-gated calcium channel.

3. In a lazy person, more glucose is going into glycogen storage.

4. Glut4 is always expressed.

5. The net effect of amylin is to...

6. Glucagon activates phosphorylase to stimulate glycogenolysis.

7. LJ's wife comes into your pharmacy. She is a 40-year-old caucasian female coffee drinker with high triglycerides but no family history. She is wondering if the ADA recommends that she be screened for diabetes? She has never been screened before. You tell her...

8. Insulin in the portal vein, _________ gluconeogenesis in the liver.

9. Epinephrine may also increase glycogenolysis and gluconeogenesis.

10. Glut 2 is a non-inducible glucose transporter?

11. Nephrogenic DI and genetic DI are deficiencies in AVP ________

12. How much glucose should you take (to try to get your blood sugar up) before you call the hospital?

13. The muscles lack of G6P phosphatase ensures oxidation?

14. Normal urine output is between _____ mL/kg/day.

15. Amylin

16. Hexokinase II has a high Km.

17. Glucagon stimulates acetyl Co-A carboxylase.

18. In type 2 diabetics, GIP and GLP-1 secretion are usually reduced.

19. DKA is generally seen in...

20. Insulin secretion from the beta-cell involves what?

21. GLP-1

22. What drugs can cause secondary diabetes mellitus?

23. GLP-1

24. The diagnostic triad of DKA involves

25. Insulin