Pancreatic Hormones & Antidiabetic Drugs Quiz

18 Questions | By Catherinehalcomb | Last updated: Mar 21, 2022 | Total Attempts: 147

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Pancreatic Hormones & Antidiabetic Drugs Quiz - Quiz

Take this Pancreatic Hormones & Antidiabetic Drugs Quiz to test your knowledge regarding the hormones secreted by pancreas glands and antidiabetic drugs. The following quiz consists of 18 questions. Do you know Insulin hormone controls the body's blood sugar (glucose) level? Also, you'd get a chance to learn more about Insulin and other types of antidiabetic drugs. So, are you ready to take up the quiz? Let's start then. All the best!

Questions and Answers

1.

Which of the following is true in regard to Insulin?
- A.
  
  It needs opening of K+ channels to be secreted from B-cells
- B.
  
  It needs closure of K+ channels to be secreted from B-cells.
- C.
  
  It needs closure of Ca+2 channels to be secreted from B-cells
- D.
  
  The ATP/ADP ratio is in favour of ADP
2.

Regarding Insulin, the following are true, except:
- A.
  
  It causes gluconeogenesis.
- B.
  
  It is a peptide.
- C.
  
  It may cause hypoglycaemia
- D.
  
  Insulin lispro in an ultra short acting preparation
3.

Which of the following is not true in regard to Insulin:
- A.
  
  Insulin is small protein comprising 51 amino acids residues
- B.
  
  Synthesized in the B-cells of (the Langerhans via its precursor, proinsulin
- C.
  
  One molecule of proinsulin is cleaved by enzymes to give one molecule of insulin and one molecule of ( -peptide
- D.
  
  In the muscles, Insulin inhibits anabolism, and induces protein catabolism, and decrease amino acids transport.
4.

Beef Insulin differs from human insulin by
- A.
  
  3 amino acids
- B.
  
  2 amino acids
- C.
  
  1 amino acids
- D.
  
  4 amino acids
5.

Pork Insulin differs from human insulin by
- A.
  
  2 amino acids
- B.
  
  3 amino acids
- C.
  
  1 amino acids
- D.
  
  4 amino acids
6.

In regard to Insulin molecule which of the following is true?
- A.
  
  Pork insulin differs from human insulin by 1 amino acid.
- B.
  
  Beef insulin differs from human insulin by 3 amino acid
- C.
  
  Secreted with C-peptide in equimolar portions from the B-cells.
- D.
  
  All of the above.
7.

Which of the following insulines is rapid and long acting Insulin?
- A.
  
  Insulin lispro
- B.
  
  Insulin aspart
- C.
  
  Insulin exubera
- D.
  
  Insulin glargine.
- E.
  
  Insulin soluble (regular).
8.

Insulin glargine is:
- A.
  
  Short acting clear insulin
- B.
  
  Rapid acting clear insulin
- C.
  
  Short acting cloudy insulin
- D.
  
  All of the above
9.

The most dangerous adverse effects of Insulin is:
- A.
  
  Hypoglycaemia
- B.
  
  Weight gain
- C.
  
  Allergic reactions
- D.
  
  Subcutancous lipodystrophy
10.

Biguanides are :
- A.
  
  Antihypertensive drugs
- B.
  
  Antidiabetic drugs
- C.
  
  Antiemetic drugs
- D.
  
  Antidiarcal drugs
11.

Which one of the following drugs promotes the release of endogenous insulin?
- A.
  
  Acarbose
- B.
  
  Canagliflozin
- C.
  
  Glipizide
- D.
  
  Metformin
- E.
  
  Pioglitazone
12.

Which of the following is an important effect of insulin?
- A.
  
  Increased conversion of amino acids into glucose
- B.
  
  Increased gluconeogenesis
- C.
  
  Increased glucose transport into cells
- D.
  
  Inhibition of lipoprotein lipase
- E.
  
  Stimulation of glycogenolysis
13.

Which of the following drugs is most likely to cause hypoglycemia when used as monotherapy in the treatment of type 2 diabetes?
- A.
  
  Acarbose
- B.
  
  Canagliflozin
- C.
  
  Glyburide
- D.
  
  Metformin
- E.
  
  Miglitol
14.

Which of the following is not true concerning Metformin?
- A.
  
  It works by reducing hepatic glucose output
- B.
  
  It works by enhancing insulin sensitivity in peripheral tissues
- C.
  
  It reduces the plasma triglycerides level.
- D.
  
  It works by enhancing insulin release from the B-cells of pancreas.
15.

A glucosidase inhibitor (Acarbose) is
- A.
  
  Antihypertensive drugs
- B.
  
  Insulin releasing drug
- C.
  
  Antithyroid agent
- D.
  
  Non of the above.
16.

Which of the following about a-glucosidase inhibitors is not true?
- A.
  
  They have a direct effect on insulin release.
- B.
  
  They slow the digestion of complex carbohydrates in GIT.
- C.
  
  Can be used with oral hypoglycacmic drugs
- D.
  
  Their common adverse effects are flatulence and bloating.
- E.
  
  Miglitol is one example of these drugs.
17.

Acarbose is
- A.
  
  Drug that increase complex carbohydrate absorption from GlT.
- B.
  
  Drug that inhibits lactase enzyme.
- C.
  
  Drug that inhibits MAO-B selectivity.
- D.
  
  Abdominal distention and flatulence are common adverse effects
18.

Which of the following oral hypoglycaemic agents can cause lactic acidosis?
- A.
  
  Tolbutamide
- B.
  
  Glyburide
- C.
  
  Glipizide
- D.
  
  Phenfomine