The Hardest Microbiology Questions And Answers! Quiz

70 Questions | Total Attempts: 779

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The Hardest Microbiology Questions And Answers! Quiz

The study of microbiology has made a significant impact on the medical industry, and there are a lot of things that one can learn through it and come up with solutions to some of the issues we are facing with some illnesses. Do you think you have what it takes to tackle the hardest microbiology exam? Take up the quiz below and get to find out!


Questions and Answers
  • 1. 
    Who is usually credited with the discovery of penicillin?  
    • A. 

      Fleming

    • B. 

      Florey and Chain

    • C. 

      Duchesne

    • D. 

      Ehrlich

  • 2. 
    Whose discovery of streptomycin stimulated an intense search for other antibiotics?  
    • A. 

      Waksman

    • B. 

      Ehrlich

    • C. 

      Fleming

    • D. 

      Pasteur

  • 3. 
    The use of arsenic compound Salvarsan as a treatment for syphilis is credited to  
    • A. 

      Fleming

    • B. 

      Ehrlich

    • C. 

      Waksman

    • D. 

      Chain

  • 4. 
    Chemotherapeutic agents that are natural products of microorganisms are most specifically referred to as __________.  
    • A. 

      Antimicrobial agents


    • B. 

      Synthetic drugs

    • C. 

      Antibiotics

    • D. 

      Semisynthetic drugs

  • 5. 
    Who is generally credited with the discovery of sulfanilamide as a chemotherapeutic agent?  
    • A. 

       Gerhard Domagk

    • B. 

      Ernest Duchesne

    • C. 

      Ernst Chain

    • D. 

       Robert Koch

  • 6. 
    ________ __________ are activities of a chemotherapeutic agent that damage the host either by inhibiting the same process in the host as in the target cell or by damaging other processes. (2 words)  
  • 7. 
     The minimum lethal concentration (MLC) is the lowest concentration of drug from which organisms fail to recover when removed from the drug.  
    • A. 

      True

    • B. 

      False

  • 8. 
    Agents that are static and, therefore, do not kill infecting microorganisms are not useful as chemotherapeutic agents.  
    • A. 

      True

    • B. 

      False

  • 9. 
    A drug that disrupts a microbial function not found in animal cells usually has a higher therapeutic index.  
    • A. 

      True

    • B. 

      False

  • 10. 
    The drug level required for the clinical treatment of a particular infection is called the  
    • A. 

      Therapeutic dose.


    • B. 

      Toxic dose.

    • C. 

      Therapeutic index.


    • D. 

      Minimal inhibitory concentration.

  • 11. 
    Which of the following inhibits protein synthesis?  
    • A. 

      Dapsone

    • B. 

      Erythromycin

    • C. 

      Penicillin

    • D. 

      Isoniazid

  • 12. 
    Which of the following is likely to have the most toxic side effects to humans?  
    • A. 

      inhibitors of cell wall synthesis

    • B. 

        inhibitors of protein synthesis 


    • C. 

      disrupters of cell membrane structure 


    • D. 

      Inhibitors of DNA synthesis

  • 13. 
     Isoniazid is a narrow-spectrum antibiotic that  
    • A. 

      Is not useful as a chemotherapeutic agent.

    • B. 

      Is one of the few drugs effective against Mycobacterium tuberculosis.

    • C. 

       is one of the few drugs effective against systemic fungal infections.


    • D. 

      None of the choices

  • 14. 
    Consider an antibacterial drug. In which of the following cases would the action of the drug be considered primarily bacteriostatic?  
    • A. 

      The minimal lethal concentration (MLC) is equal to the minimal inhibitory concentration (MIC).

    • B. 

      The MLC is lower than the MIC.

    • C. 

      The MLC is 2-4 times higher than the MIC.

    • D. 

      The MLC is 10-20 times higher than the MIC.

  • 15. 
    Chemotherapeutic agents that are chemically modified natural products of microorganisms are most specifically referred to as __________.  
    • A. 

      Antimicrobial agents


    • B. 

      Synthetic drugs


    • C. 

      Antibiotics


    • D. 

       semisynthetic drugs

  • 16. 
    Chemotherapeutic agents that are artificially produced are most specifically referred to as __________.  
    • A. 

      Antimicrobial agents


    • B. 

      Synthetic drugs

    • C. 

      Antibiotics

    • D. 

      Semisynthetic drugs

  • 17. 
    The ratio of toxic dose to therapeutic dose is called the  
    • A. 

      Toxicity index.

    • B. 

      Phenol coefficient.


    • C. 

      Therapeutic index.

    • D. 

      Susceptibility quotient.

  • 18. 
    The minimal lethal concentration (MLC) is the  
    • A. 

      lowest concentration of a drug that prevents growth of a particular pathogen.

    • B. 

      Highest concentration of a drug that prevents growth of a particular pathogen.

    • C. 

      Lowest concentration of a drug that kills a particular pathogen.

    • D. 

      Highest concentration of a drug that kills a particular pathogen.

  • 19. 
     The lowest concentration of an antibiotic that prevents growth is the  
    • A. 

      Minimal inhibitory concentration (MIC). 


    • B. 

      Minimal lethal concentration (MLC). 


    • C. 

      50% inhibitory dose.

    • D. 

      All of the choices

  • 20. 
    Which of the following is a desirable general characteristic of antimicrobial drugs?  
    • A. 

       selective toxicity


    • B. 

      Broad-spectrum of activity


    • C. 

      Bactericidal rather than bacteriostatic

    • D. 

      All of the choices

  • 21. 
    When a chemotherapeutic agent is effective against many different pathogens, it is said to be a __________ antibiotic.  (2 words)  
  • 22. 
     In a disk diffusion assay for drug susceptibility, a drug producing a larger clear zone is always more effective than a drug than to one producing a smaller clear zone.  
    • A. 

      True

    • B. 

      False

  • 23. 
    Which of the following affects the size of the clear zone in a disk diffusion test of antimicrobial susceptibility?  
    • A. 

       the initial concentration of the drug


    • B. 

       the solubility of the drug


    • C. 

      The diffusion rate of the drug

    • D. 

      All of the choices

  • 24. 
    The E test is  
    • A. 

      A rapid serological test used to detect the presence of eastern equine encephalitis virus in cerebrospinal fluid.

    • B. 

      A quantitative antibiotic sensitivity test that utilizes plastic strips impregnated with an antibiotic of interest.

    • C. 

      Used to quantify levels of IgE antibody in serum samples. 


    • D. 

      Used to measure esculine levels in pasteurized milk.

  • 25. 
    In the broth dilution test, the highest concentration of the antibiotic resulting in no growth after 16 to 20 hours of incubation is the MIC.  
    • A. 

      True

    • B. 

      False

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