Quiz Over Chapter 17 Microbiology

The ability of the body to specifically react to a microbial infection. It usually includes a memory component & is acquired during the life of the individual.

Glycoprotein that reacts with (binds to) antigen

Have at least two binding sites for antigens; valence= number of binding sites

Recognize antigens in association with MHCs on APCs

Based on functions & cell surface glycoproteins called CDs (clusters of differentiations)

Classified as CD4 which are adhesion molecules that bind to MHC class II molecules  on APCs; after binding APC, CD4 cells differentiate into Th1 and Th2 cells; Th1 cells secrete cytokines that stimulate other immune cells and also enable macrophages to degrade microbes that have invaded them; Th2 cells associated with parasitic infections and allergic reactions

Classified as CD8 which are adhesions that bind MHC class I molecules; when activated by Th cell, Tc cells become cytotoxic T lymphocytes (CTLs) which can lyse target cells (target cells have endogenous antigen combined with MHC molecule) or induce apoptosis; CTLs release perforin, then granzymes are allowed to enter cell 

Appear to suppress other T cells

Chemicals by which cells of immune system communicate with each other

1st encounter with pathogen (antigen); appearance of IgM, followed by IgG; antibody increase is slow

More rapid; IgM production same as in primary response, but there is a rapid rise in IgG due to memory cell activity; antibody peak in 2-7 deays