1.
The pulmonary artery carries oxygenated blood.
Correct Answer
B. False
Explanation
The pulmonary artery does not carry oxygenated blood. It carries deoxygenated blood from the heart to the lungs, where it picks up oxygen and gets oxygenated. The oxygenated blood is then returned to the heart through the pulmonary veins. Therefore, the statement that the pulmonary artery carries oxygenated blood is false.
2.
The sympathetic nervous system increases heart rate.
Correct Answer
A. True
Explanation
The sympathetic nervous system is responsible for the "fight or flight" response in the body, which prepares the body for action. One of the effects of this response is an increase in heart rate. When the sympathetic nervous system is activated, it releases epinephrine (adrenaline) which stimulates the heart to beat faster, increasing blood flow to the muscles and organs. Therefore, it can be concluded that the statement "The sympathetic nervous system increases heart rate" is true.
3.
The nephron is the basic unit of the nervous system.
Correct Answer
B. False
4.
Peripheral vascular resistance is the resistance offered by the peripheral blood vessel.
Correct Answer
A. True
Explanation
Peripheral vascular resistance refers to the resistance that the blood encounters as it flows through the peripheral blood vessels. These blood vessels include arteries, arterioles, capillaries, venules, and veins. The resistance is primarily determined by the diameter of the blood vessels and the tone of the smooth muscles in their walls. When the blood vessels constrict or narrow, the resistance increases, and when they dilate or widen, the resistance decreases. Therefore, it is true that peripheral vascular resistance is the resistance offered by the peripheral blood vessels.
5.
Systolic blood pressure the pressure exerted during relaxation.
Correct Answer
B. False
Explanation
Systolic blood pressure is actually the pressure exerted on the walls of the arteries when the heart contracts and pumps blood into the circulation. It is the higher number in a blood pressure reading and represents the maximum pressure in the arteries. On the other hand, diastolic blood pressure is the pressure exerted on the walls of the arteries when the heart is at rest between beats. Therefore, the statement that systolic blood pressure is the pressure exerted during relaxation is incorrect.
6.
Pre-load is directly proportional to peripheral resistance.
Correct Answer
B. False
Explanation
Pre-load is not directly proportional to peripheral resistance. Pre-load refers to the amount of blood in the ventricles at the end of diastole, before it is pumped out during systole. Peripheral resistance, on the other hand, refers to the resistance encountered by the blood flow in the blood vessels. These two factors are not directly related, as pre-load is influenced by factors such as venous return and blood volume, while peripheral resistance is influenced by factors such as vessel diameter and vessel length. Therefore, the correct answer is false.
7.
Renin is released by the liver.
Correct Answer
B. False
Explanation
Renin is not released by the liver. Renin is actually released by specialized cells in the kidneys called juxtaglomerular cells. These cells are located in the walls of the afferent arterioles, which are blood vessels that supply the kidneys. Renin plays a crucial role in the regulation of blood pressure and the renin-angiotensin-aldosterone system.
8.
95% of the hypertensives have primary / essential hypertension.
Correct Answer
A. True
Explanation
The given statement suggests that the majority of people with high blood pressure have primary or essential hypertension. This means that their high blood pressure is not caused by any underlying medical condition or specific cause, but rather it is a chronic condition that develops over time. This is a commonly observed trend in the medical field, where primary hypertension is the most prevalent form of high blood pressure. Therefore, the answer "True" is supported by the statement.
9.
One of the mechanisms of regulation of blood pressure is done through a baroreceptor reflex.
Correct Answer
A. True
Explanation
The statement is true. The baroreceptor reflex is a mechanism that helps regulate blood pressure. Baroreceptors are specialized nerve cells located in the walls of certain blood vessels, particularly in the carotid sinus and aortic arch. They detect changes in blood pressure and send signals to the brain, which then triggers responses to either increase or decrease blood pressure to maintain homeostasis. This reflex helps ensure that blood pressure remains within a normal range and prevents it from becoming too high or too low.
10.
The pancreas is both an endocrine as well as an exocrine organ.
Correct Answer
A. True
Explanation
The pancreas is an organ in the body that serves both endocrine and exocrine functions. As an endocrine organ, it produces and releases hormones such as insulin and glucagon into the bloodstream to regulate blood sugar levels. As an exocrine organ, it secretes digestive enzymes into the small intestine to aid in the digestion of food. Therefore, the statement that the pancreas is both an endocrine and exocrine organ is true.
11.
Glucagon decreases hepatic glucose production.
Correct Answer
B. False
Explanation
Glucagon actually increases hepatic glucose production. It is a hormone that is released by the pancreas in response to low blood sugar levels. Glucagon acts on the liver to stimulate the breakdown of glycogen into glucose, which is then released into the bloodstream to increase blood sugar levels. Therefore, the given statement is incorrect.
12.
99% part of the pancreas is the exocrine part.
Correct Answer
A. True
Explanation
The pancreas is a gland that performs both endocrine and exocrine functions. The exocrine part of the pancreas, which accounts for approximately 99% of its mass, secretes digestive enzymes into the small intestine to aid in the digestion of food. These enzymes include amylase, lipase, and protease. The remaining 1% of the pancreas is made up of endocrine cells called islets of Langerhans, which secrete hormones such as insulin and glucagon directly into the bloodstream to regulate blood sugar levels. Therefore, it is true that 99% of the pancreas is the exocrine part.
13.
The fraction of Drug reaching circulation and available for Action is called Bioavailability.
Correct Answer
A. True
Explanation
Bioavailability refers to the fraction of a drug that reaches the systemic circulation and is available to produce its intended pharmacological effect. This includes the portion of the drug that is absorbed into the bloodstream after administration and is not metabolized or excreted before reaching its target site of action. Therefore, the statement that the fraction of drug reaching circulation and available for action is called bioavailability is true.
14.
Cardiac output = _________________________ X _________________________
Correct Answer
heart rate stroke volume
Explanation
The cardiac output is determined by the heart rate and stroke volume. The heart rate refers to the number of times the heart beats per minute, while the stroke volume is the amount of blood pumped out of the heart with each beat. To calculate the cardiac output, these two factors are multiplied together. Therefore, the correct answer is heart rate multiplied by stroke volume.
15.
(13) Blood pressure = _________________________ X ________________________
Correct Answer
cardiac output peripheral resistance
Explanation
Blood pressure is determined by two factors: cardiac output and peripheral resistance. Cardiac output refers to the amount of blood pumped by the heart per minute, while peripheral resistance refers to the resistance encountered by the blood flow in the blood vessels. When the cardiac output increases or the peripheral resistance decreases, blood pressure tends to rise. Conversely, when the cardiac output decreases or the peripheral resistance increases, blood pressure tends to decrease. Therefore, the correct answer is that blood pressure is determined by the product of cardiac output and peripheral resistance.
16.
Two class of drugs which act on the RAAS system are ____________ & _____________
Correct Answer
ACE inhibitors ARB's
Angiotensin converting enzyme inhibitors Angiotensin receptor blockers
angiotensin converting enzyme inhibitors angiotensin receptor blockers
Explanation
ACE inhibitors and ARBs (Angiotensin receptor blockers) are two classes of drugs that act on the RAAS (Renin-Angiotensin-Aldosterone System) system. ACE inhibitors work by inhibiting the enzyme that converts angiotensin I to angiotensin II, while ARBs work by blocking the receptors that angiotensin II binds to. Both drugs are commonly used to treat hypertension and heart failure.
17.
When RAAS system gets activated __________________is released by the kidney.
Correct Answer
renin
Explanation
When the RAAS (Renin-Angiotensin-Aldosterone System) system gets activated, the kidney releases renin. This is because renin is an enzyme produced and released by the kidney in response to low blood pressure or low blood volume. Renin plays a crucial role in the regulation of blood pressure by initiating a series of reactions that ultimately lead to the production of angiotensin II, a potent vasoconstrictor. This vasoconstriction helps to increase blood pressure and maintain adequate blood flow to vital organs.
18.
Blocking of ----------------- receptor by ARB’s results in to _______________________, ________________________,
Correct Answer
AT1 vasodilation increased aldosterone levels
Explanation
Blocking of AT1 receptors by ARBs (angiotensin receptor blockers) results in vasodilation, which means relaxation and widening of blood vessels. This leads to decreased resistance in the blood vessels, allowing for easier blood flow and lower blood pressure. Additionally, blocking AT1 receptors also causes an increase in aldosterone levels. Aldosterone is a hormone that regulates electrolyte balance and fluid volume in the body. Increased aldosterone levels can result in increased sodium and water retention, which further contributes to the regulation of blood pressure.
19.
Pharmaco kinetics is what drug does to the body.
Correct Answer
B. False
Explanation
The statement that "Pharmacokinetics is what drug does to the body" is false. Pharmacokinetics refers to what the body does to the drug, including its absorption, distribution, metabolism, and excretion. It is the study of how the drug is absorbed, distributed, metabolized, and eliminated by the body over time.
20.
Pharmacodynamics is what body does to the drug.
Correct Answer
B. False
Explanation
The statement is incorrect. Pharmacodynamics is actually the study of what the drug does to the body, not the other way around. It focuses on the effects of the drug on the body, including its mechanism of action, therapeutic effects, and side effects.