Hello and welcome to a wonderful quiz on pharmacology, where today we’ll be looking at the topic of immunomodulators – drugs used to help regulate the immune system, which are used for such ailments as asthma and angioedema. What can you tell us about these drugs? Let’s find out.
Kidney failure
Lymphomas
Infections
Neurologic disorders
Myelosuppression
Hepatic failure
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Tacrolimus - increases the catabolism of IgG antibodies
Azathioprine - stimulates interleukin-2 synthesis in CD4 helper cells
Sirolimus - inhibits mammalian kinase
Cyclophosphamide - inhibits inosine monophosphate dehydrogenase
Muromonab-CD3 - inhibits calcineurin
Daclizumab - blocks interleukin-2 receptors
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Azithromycin
Azathioprine
Tacrolimus
Cyclosporine
Tobramycin
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Etanercept
Infliximab
Muromonab CD3
Tacrolimus
Aldesleukin
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Infliximab
Prednisone
BCG vaccine
Interferon-beta-1b
Aldesleukin
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Inhibition of plasma cholinesterase
Activation of Nm receptors
Stimulation of synthesis of interleukin 2
Inhibition of T cell activation and proliferation
Stimulation of synthesis of interleukin 1
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Azathioprine, prednisone, aldesleukin
Cyclosporine, azathioprine, prednisone
Prednisone, triamcinolone, cyclosporine
Aldesleukin, infliximab, etanercept
Infliximab, etanercept, triamcinolone
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Prednisone and cyclosporine
Cyclosporine and erythromycin
Cyclophosphamide and doxorubicin
Vinblastine and prednisone
Doxorubicin and vinblastine
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Macrophages
Dendritic cells
T-helper cells
Plasma cells
Natural killer cells
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Prednisone
Cyclosporine
Azathioprine
Theophylline
Diltiazem
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Aldesleukin
Vinblastine
Tacrolimus
Fluorouracil
Paclitaxel
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Blockade of receptors of TNF-alpha
Inhibition of clonal expansion of T and B lymphocytes
Inhibition of antigen presentation by dendritic cells
Stimulation of genetic expression of interleukin 2
Stimulation of macrophage phagocytic activity
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Cyclosporine
Dobutamine
Dopamine
Azathioprine
Fluorouracil
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It inhibits antibody formation by plasma cells
It inhibits several enzymes involved in purine metabolism
It inhibits calcineurin enzyme in T cell cytoplasm
It stimulates the synthesis of interleukin-1 in T cells
It neutralize a surface protein receptor complex in T cells
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It prevents placental crossing of Rho(D) positive erythrocytes in subsequent pregnancies
It blocks the production of maternal antibodies against Rho(D) positive erythrocytes
It prevents the hemolytic disease of the mother in subsequent pregnancies
It blocks the production of fetal Rho(D) positive erythrocytes in subsequent pregnancies
It prevents the placental crossing of fetal Rho(D) antibodies in subsequent pregnancies
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Its immunosuppressant activity is definitely superior to that of azathioprine
It has significantly less adverse effects than azathioprine
It has drastically reduced the risk of graft versus host disease
It selectively inhibits macrophage-mediated production of several interleukins
It selectively inhibits antigen recognition by antigen presenting cells
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It induces proliferation and differentiation of B and T lymphocytes
It inhibits macrophage phagocytic activity
It inhibits antigen presentation by dendritic cells
It decreases the synthesis of calcineurin
It inhibits the activity of natural killer cells
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Trastuzumab
Infliximab
Interferon beta-1b
Prednisone
Tacrolimus
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Inhibition of catabolism of IgG antibodies
Inhibition of macrophage-mediated production of interleukin 1
Activation of several immunophilins
Early activation of T lymphocytes
Activation of phospholipase A2
Inhibition of T cell-mediated production of interleukin 2
Direct lympholythic effect on cytotoxic T cells
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