Biochemistry And Analytical Biochemistry Quiz

58 Questions | Total Attempts: 406

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Questions and Answers
  • 1. 
    1. The glycolytic pathway (glucose to 2 Pyruvate) is found
    • A. 

      In most living organisms

    • B. 

      In all living organisms

    • C. 

      Primarily in animals

    • D. 

      Only in eukaryotes

  • 2. 
    In Eukaryotic cells, the enzymes of glycolysis are located in the
    • A. 

      Plasma membrane

    • B. 

      Inner mitochondrial membrane

    • C. 

      Cytosol

    • D. 

      Mitochondrial matrix

  • 3. 
    In glycolysis ATP synthesis is catalysed by
    • A. 

      Hexokinase

    • B. 

      6-phosphofructo-1-kinase

    • C. 

      Glyceraldehaye 3-phosphate dehaydrogenase

    • D. 

      Phosphoglycerate kinase

  • 4. 
    The regulation of the glycolytic pathway involves
    • A. 

      Feedback inhibition by ATP.

    • B. 

      Allosteric inhibition by ATP.

    • C. 

      Allosteric stimulation by ADP

    • D. 

      All three are correct.

  • 5. 
    In Glycolysis, the metabolism of 3 molecules of Glucose will consume how many molecules of ATP?
    • A. 

      2

    • B. 

      6

    • C. 

      12

    • D. 

      36

  • 6. 
    The irreversible reactions of glycolysis include that catalysed by
    • A. 

      Phosphoglucose isomerase

    • B. 

      Phosphofructokinase

    • C. 

      Fructose bisphosphate aldolase

    • D. 

      Glyceraldehydes 3-phosphate dehydrogenase

  • 7. 
    In a eukaryotic cell, most of the enzymes of the citric acid cycle are located in the
    • A. 

      Mitochondrial matrix

    • B. 

      Inner mitochondrial membrane.

    • C. 

      Intermembrane space.

    • D. 

      Outer mitochondrial membrane.

  • 8. 
    In a eukaryotic cell, most of the enzymes of the electron transport chain are located in the
    • A. 

      Cytosol

    • B. 

      Outer mitochondrial membrane.

    • C. 

      Intermembrane space.

    • D. 

      Inner mitochondrial membrane.

  • 9. 
    Pyruvate, the end product of glycolysis, enters the citric acid cycle after it has been converted to
    • A. 

      Acetaldehyde.

    • B. 

      Lactic acid.

    • C. 

      Acetic acid.

    • D. 

      Acetyl-CoA.

  • 10. 
    Most of the ATP made during cellular respiration is generated by:
    • A. 

      Substrate-level phosphorylation.

    • B. 

      Oxidative phosphorylation.

    • C. 

      Glycolysis.

    • D. 

      Photophosphorylation.

  • 11. 
    A biological redox reaction always involves:
    • A. 

      A loss of electrons

    • B. 

      A gain of electrons.

    • C. 

      A reducing agent.

    • D. 

      All of the above.

  • 12. 
    Which of the following is not a significant biological oxidizing agent?
    • A. 

      Fe3+

    • B. 

      FAD

    • C. 

      NAD+

    • D. 

      Ubiquinone (a.k.a. CoQ)

  • 13. 
    During electron transport, protons are pumped out of the mitochondrion at each of the major sites except for:
    • A. 

      Complex I

    • B. 

      Complex II

    • C. 

      Complex III

    • D. 

      Complex IV

  • 14. 
    Gluconeogenesis is
    • A. 

      The formation of glycogen

    • B. 

      The formation of starches

    • C. 

      The formation of glucose from non-carbohydrates

    • D. 

      The formation of glucose from other carbohydrates

  • 15. 
    The sequence of glucose oxidation to lactate in peripheral tissues, delivery of lactate to the liver, formation of glucose from lactate in the liver, and delivery of glucose back to peripheral tissues is known as theā€¦
    • A. 

      Glyoxylate cycle

    • B. 

      Krebs cycle

    • C. 

      Cori Cycle

    • D. 

      Gluconeogenesis cycle

  • 16. 
    Where is the site of most gluconeogenesis in mammals?
    • A. 

      Liver

    • B. 

      Pancreas

    • C. 

      Kidney

    • D. 

      Small Intestine

  • 17. 
    Which molecule cannot be directly transported from the mitochondria to the cytosol?
    • A. 

      Oxaloacetate

    • B. 

      Acetate

    • C. 

      Malate

    • D. 

      Phosphoenolpyruvate

  • 18. 
    Hormonal induction of PEP carboxylase (PEPCK) refers to
    • A. 

      The increase of enzyme activity by glucagon

    • B. 

      The decrease of enzyme activity by insulin

    • C. 

      Triggering gene expression increasing transcription

    • D. 

      The elevation of cAMP on fasting

  • 19. 
    At high glucagon concentrations, gluconeogenesis will be favoured over glycolysis
    • A. 

      True

    • B. 

      False

  • 20. 
    Regulation of the tricarboxylic acid cycle activity in vivo may involve the concentration of all of the followingEXCEPT
    • A. 

      Acetyl CoA

    • B. 

      ADP

    • C. 

      ATP

    • D. 

      CoA

  • 21. 
    Gluconeogenesis uses the same enzymatic reactions of glycolysis except for
    • A. 

      Pyruvate Kinase

    • B. 

      4 irreversible reactions in glycolysis

    • C. 

      3 irreversible reactions in glycolysis

    • D. 

      2 irreversible reactions in glycolysis

  • 22. 
    Glycogen synthesis requires ( ) to activate glucose 1 phosphate
    • A. 

      ATP

    • B. 

      ADP

    • C. 

      UTP

    • D. 

      UDP

  • 23. 
    Glycogenolysis (breakdown of glycogen) occurs in
    • A. 

      Muscle

    • B. 

      Liver

    • C. 

      Muscle and liver

    • D. 

      Pancreas

  • 24. 
    The enzyme which catalyzes the key regulatory step in glycogen biosynthesis is
    • A. 

      Glycogen synthase

    • B. 

      Debranching enzyme

    • C. 

      Phosphoglucomutase

    • D. 

      UDP-glucose pyrophosphorylase

  • 25. 
    Glycogen Phosphorylase is (more/less) active when phosphorylated and it is (activated/inhibited) by glucose 6 phosphate
    • A. 

      More; activated

    • B. 

      Less; activated

    • C. 

      More; inhibited

    • D. 

      Less; inhibited

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