Blood Bank Final

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Blood Bank Final - Quiz

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Questions and Answers
  • 1. 
    What is a cold panel?
  • 2. 
    What are the four different mechanisms of drug induced red cell sensitization?
  • 3. 
    List those who are at risk for TA-GVHD
  • 4. 
    List the disease testing that is performed on ALL allogeneic donor units
  • 5. 
    If your patient is type AB, what type of plasma can they receive?
  • 6. 
    List 5 Different Factors that affect sensitization
  • 7. 
    List the three mechanisms that can cause weak D
  • 8. 
    What is the equation to calculate the number of RhIg needed?
  • 9. 
    Which major types of AIHA has a non reactive eluate?
    • A. 

      WAIHA

    • B. 

      COLD

    • C. 

      MIXED

    • D. 

      PCH

  • 10. 
    Which types of AIHA's show AHG reactivity
    • A. 

      WARM

    • B. 

      COLD

    • C. 

      MIXED

    • D. 

      PCH

  • 11. 
    Which type of hemolysis is destroyed in the bloodstream releasing hemoglobin into plasma?[Blank]
  • 12. 
    Intact red cell is removed from circulation by RE system; coated with IgG
    • A. 

      Intravascular

    • B. 

      Extravascular

  • 13. 
    • Most common @ 4C
    • Low titer @ 4C
      • <64 
      • Negative DAT 
      • Can interfere with ABO typing, Rh and DAT
    • A. 

      Benign Cold Auto

    • B. 

      Pathologic cold Auto

    • C. 

      PCH

  • 14. 
    • Reactivity up to 32 C
    • Idiopathic
    • Spontaneous agglutination that disperses at 37
    • C3 only 
    • Only a problem with heart surgery - when temp is decreased 
    • A. 

      Benign

    • B. 

      Pathologic

    • C. 

      PCH

  • 15. 
    What is associated with Mycoplasma pneumoniae
    • A. 

      Benign cold auto

    • B. 

      Pathologic cold auto

    • C. 

      PCH

  • 16. 
    PCH can be associated with...
    • A. 

      Children

    • B. 

      Viral infections

    • C. 

      Age

    • D. 

      Gender

    • E. 

      Rapid intravascular hemolysis

  • 17. 
    PCH reacts at less than [Blank] C
  • 18. 
    What can aid in the detection of warm autoantibodies
    • A. 

      DAT

    • B. 

      Panels

    • C. 

      Eluates

    • D. 

      Adsorptions

  • 19. 
    Prewarm testing is done to...
    • A. 

      Remove the C3b

    • B. 

      Determine whether there are leukocytes presesnt

    • C. 

      Determine whether warm reacting antibodies are present in the serum that also contains complement binding cold antibody

    • D. 

      Determines host versus graft

  • 20. 
    • Caused by antibodies in the host to the donors WCs
    • Give leuko reduced or washed, deglyced cells 
    • Can be pretreated with anti-pyretics
    • Increase in 1C without any causes
    • A. 

      IHTR

    • B. 

      TRALI

    • C. 

      Febrile

    • D. 

      DHTR

  • 21. 
    Symptoms include: erythema, pruritis, hives IgEVery mild and non-life threateningTreat with benadryl
    • A. 

      Febrile

    • B. 

      TRALI

    • C. 

      TACO

    • D. 

      Allergic

  • 22. 
    • Symptoms: mild jaundice, fever and decrease hct/hgb
    • Anamnestic response - previously sensitized 
    • Extravascular 
    • No complement activation 
    • DAT positive
    • Occurs 3 - 7 days after transfusion
    • A. 

      Immediate Hemolytic Transfusion Rxn

    • B. 

      Febrile

    • C. 

      Transfusion related acute lung Injury

    • D. 

      Delayed Hemolytic Transfusion Rxn

  • 23. 
    • The transfusion of the donor's antibodies to the recipient white cells 
    • Complement is activated
    • Symptoms: chills, cough, fever, cyanosis, hypotension, increased respiratory distress
    • X-ray would show pulmonary edema
    • Give leuko reduced 
    • A. 

      Immediate Hemolytic Transfusion Rxn

    • B. 

      Delayed hemolytic transfusion rxn

    • C. 

      Transfusion Related Acute Lung Injury

    • D. 

      Anaphylactic

  • 24. 
    Transfusion of donor IgA to a patient with IgA antibodies, can be characterized with NO FEVER & abdominal cramps. Symptoms also includes coughing, dyspnea, nausea, flushing, chest pain.  
    • A. 

      TRALI

    • B. 

      Anaphylactic

    • C. 

      TACO

    • D. 

      Bacterial contamination

  • 25. 
    What are common to cause bacterial contamination in TRs?
    • A. 

      Serratia specie

    • B. 

      Pseudomonas aerguginosa

    • C. 

      Campylobacterm pseudomona

    • D. 

      Yersinia enterocolitica

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