Alzheimer's Pharmacology (Hoyt)

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1. Rivastigmine (Exelon), an cholinesterase inhibitor used in AD, has a greater potency for one of the two isoforms of AChE in the brain because with AD progression, there is preferential loss of one of the isoforms and thus the drug targets the one that IS remaining. Which isoform does rivastigmine (Exelon) target?

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Pharmacology Quizzes & Trivia

A person suffering from Alzheimer’s disease calls for specialized care and treatment. As a medical practitioner how well do you understand the disease and drugs prescribed to the patient? Take up the simple quiz on Alzheimer’s pharmacology and let the results speak for themselves. All the best as you tackle... see moreit! see less

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2. Memantine (Namenda) is a ______ antagonist at the NMDA receptor which is a channel of ____ and ____ ions.

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3. Which of the following enzymes are important in choline signaling that is considerably reduced in the development of AD? (Check TWO that apply)

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4. Which of the cholinesterase inhibitors used in AD is also a positive allosteric modulator of nicotinic acetylcholine receptors to synergistically increase the [acetylcholine] in the synapse?

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5. The pathogenesis of AD is associated with loss of brain tissue and neurons in which areas of the brain? (Check all that apply)

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Rivastigmine (Exelon), an cholinesterase inhibitor used in AD, has a...
Memantine (Namenda) is a ______ antagonist at the NMDA receptor which...
Which of the following enzymes are important in choline signaling that...
Which of the cholinesterase inhibitors used in AD is also a positive...
The pathogenesis of AD is associated with loss of brain tissue and...
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