Alzheimer's Pharmacology (Hoyt)

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  • 1/5 Questions

    Rivastigmine (Exelon), an cholinesterase inhibitor used in AD, has a greater potency for one of the two isoforms of AChE in the brain because with AD progression, there is preferential loss of one of the isoforms and thus the drug targets the one that IS remaining. Which isoform does rivastigmine (Exelon) target?

    • G1 (monomer)
    • G4 (tetramer)
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About This Quiz

A person suffering from Alzheimer’s disease calls for specialized care and treatment. As a medical practitioner how well do you understand the disease and drugs prescribed to the patient? Take up the simple quiz on Alzheimer’s pharmacology and let the results speak for themselves. All the best as you tackle it!

Pharmacology Quizzes & Trivia

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  • 2. 

    Memantine (Namenda) is a ______ antagonist at the NMDA receptor which is a channel of ____ and ____ ions.

    • Uncompetitive; sodium; potassium

    • Uncompetitive; sodium; calcium

    • Competitive; potassium; magnesium

    • Competitive; magnesium; calcium

    Correct Answer
    A. Uncompetitive; sodium; calcium
  • 3. 

    Which of the following enzymes are important in choline signaling that is considerably reduced in the development of AD? (Check TWO that apply)

    • Acetylcholinesterase

    • Butrylcholinesterase

    • Choline acetyltransferase

    • Nicotinic acetylcholine receptor

    Correct Answer(s)
    A. Acetylcholinesterase
    A. Choline acetyltransferase
  • 4. 

    Which of the cholinesterase inhibitors used in AD is also a positive allosteric modulator of nicotinic acetylcholine receptors to synergistically increase the [acetylcholine] in the synapse?

    • Tacrine (Cognex)

    • Donepezil (Aricept)

    • Galantamine (Razadyne)

    • Memantine (Namenda)

    • Rivastigmine (Exelon)

    Correct Answer
    A. Galantamine (Razadyne)
  • 5. 

    The pathogenesis of AD is associated with loss of brain tissue and neurons in which areas of the brain? (Check all that apply)

    • Amygdala

    • Basal forebrain

    • Frontal cortex

    • Hippocampus

    • Temporal cortex

    Correct Answer(s)
    A. Basal forebrain
    A. Frontal cortex
    A. Hippocampus
    A. Temporal cortex

Quiz Review Timeline (Updated): Mar 20, 2022 +

Our quizzes are rigorously reviewed, monitored and continuously updated by our expert board to maintain accuracy, relevance, and timeliness.

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  • Mar 20, 2022
    Quiz Edited by
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  • Apr 22, 2010
    Quiz Created by
    Teatimebarbie
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