A Practice Test On Anesthesia! Trivia Quiz
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A practice test on anaesthesia trivia quiz! There are different types of drugs given to a patient so that they can be unconscious or some parts of their body made numb of feeling. In some instances, not drugs but gasses are used. As an aspiring anaesthetic, how much do you know about different benzodiazepines, their effect as well as consumption in different types of patients? This quiz will help you find out!
- 1.Which of the following is not one of the Five Principle pharmacological effects of Benzodiazepines?
- A.
Sedation
- B.
Anxiolysis
- C.
Retrograde Amnesia
- D.
Anticonvulsant
- E.
Spinal Cord mediated skeletal muscle relaxation
- 2.Which of the Benzodiazepines reviewed has the slowest onset of action and why?
- A.
Lorazepam- due to lower lipid solubility
- B.
Midazolam- due to its water solubility
- C.
Diazepam- due to rapid redistribution
- 3.While doing a pre-op assessment on an inpatient you find that the pt is currently taking Tagamet (cimetidine) and is on a Heparin regimen. With this knowledge you know to avoid which of the benzodiazepines?
- A.
Lorazepam
- B.
Diazepam
- C.
Midazolam
- D.
Thiopental
- 4.In regards to the adjustments of Benzodiazepines in respect to the elderly patient. Would you expect to have:
- A.
Significant increase in initial dose and anticipate marked decrease in duration of action
- B.
Modest decrease in initial dose and anticipate marked increase in duration of action
- C.
No change in dose or frequency or duration from that of an healthy 25 year old patient.
- D.
None of above
- 5.The dose of Benzodiazepines required to reach a desired clinical end point is increased in the elderly compared to the younger patient.
- A.
True
- B.
False
- 6.Benzodiazepines are extensively protein bound. Therefore, in the presence of renal failure their clinical effect will be:
- A.
Shortened
- B.
Prolonged
- C.
No significant change.
- 7.Define Affinity:
- A.
Inhibit or block responses caused by an agonist
- B.
Drugs which alter the physiology of a cell by binding to plasma membrane or intracellular receptors
- C.
The strength of binding between drug and receptor
- D.
Binds to a site other than the agonist-binding domain
- 8.A drug that alters the physiology of a cell by binding to the plasma membrane or intracellular receptors is known as what?
- A.
Antagonist
- B.
Competitive Agonist
- C.
Competitive Antagonist
- D.
Agonist
- 9.What is an antagonist?
- A.
Inhibit or block responses caused by an agonist
- B.
A drug which alters the physiology of a cell by binding to plasma membrane or intracellular receptors
- C.
Biochemical messengers, often called 2ndmessengers
- D.
The strength of binding between drug and receptor
- 10.What is the MOA of Benzos?
- A.
Blockade of chloride channels leading to depolarization and inhibition of neurotransmitter
- B.
Inhibition of cyclooxygenase activity
- C.
Inhibition of GABA receptor binding which leads to degredation of GABA, preventing it from exerting it's effect.
- D.
Enhances the inhibitory effects of various neurotransmitter by facilitating GABA receptor binding. This opens chloride channels and causes hyperpolarization.
- 11.How do midazolam and diazepam compare to one another?
- A.
Midazolam has 2 times the affinity for benzo receptors
- B.
Diazepam has 3 times the affinity for benzo receptors
- C.
Diazepam is hydrophilic
- D.
Midazolam has a much londer elimination half time
- 12.All benzos share what similarities?
- A.
All are highly alkaline solutions
- B.
Composed of a benzene ring fused to a seven-membered diazepine ring
- C.
They are safe to be given during pregnancy
- D.
Composed of malonic acid and urea
- 13.How is midazolam unique in comparison to other benzos?
- A.
It is the only benzo safe to give to pregnant women.
- B.
Is known to cause pain upon injection, but has minimal respiratory depression
- C.
It is hydrophilic and becomes lipid soluble upon exposure to blood.
- D.
It is not highly protein bound like the other benzo's and thus more is available for use by the body.
- 14.Which of the following drugs will cause pain upon injection due to the solvent propylene glycol?
- A.
Lorazepam
- B.
Flumazenil
- C.
Midazolam
- D.
Diazepam
- 15.What is an appropriate oral dose for pediatric pre-medication with midazolam?
- A.
0.5 mg/kg
- B.
1 mg/kg
- C.
2-3 mg
- D.
10 - 20 mcg/ kg
- 16.What would be an appropirate Adult IV induction dose for midazolam?
- A.
0.5 mg/kg
- B.
0.1 mg/kg
- C.
2-3 mg
- D.
4 mg/kg
- 17.You have just given you pt Midazolam, how long would you expect to wait to see onset of the drug?
- A.
3-5 minutes
- B.
20-25 minutes
- C.
30-60 seconds
- D.
2 minutes
- 18.When doing a pre-op evaluation for a pt you notice the pt has low albumin levels. How would this effect the amount of Midazolam given to the pt for pre-medication?
- A.
You would need to increase the amount given in order to reach the desired effect
- B.
You would not change the dose at all.
- C.
You would decrease the amount of drug given since this pt may be at risk for overdose.
- 19.Put these medications in order of shortest elimination half time to longest: Midazolam, Diazepam, Lorazepam
- A.
Midazolam < Diazepam < Lorazepam
- B.
Diazepam < Lorazepam < Midazolam
- C.
Lorazepam < Midazolam < Diazepam
- D.
Midazolam < Lorazepam < Diazepam
- 20.What is the elimination half time of Midazolam?
- A.
21-37 hours
- B.
1-4 hours
- C.
10-20 hours
- D.
5-10 hours
- 21.What is the elimination half time of Lorazepam?
- A.
1-4 hours
- B.
21-37 hours
- C.
10-20 hours
- D.
5-10 hours
- 22.What is the elimination half time of Diazepam?
- A.
5-10 hours
- B.
1-4 hours
- C.
10-20 hours
- D.
21-37 hours
- 23.Describe the metabolism and excretion of the benzodiazepines?
- A.
Metabolized by liver and excreted in the urine
- B.
Metabolized in kidneys and excreted in feces
- C.
Metabolized by liver and excreted in feces
- D.
Metabolized in kidneys and excreted by urine
- 24.What effects do benzodiazepines exert upon the cardiovascular system?
- A.
No effect on cardiovascular system, even at high doses.
- B.
Decrease BP & PVR, especially in hypovolemic pt
- C.
Decrease ABP, CO & HR
- D.
Increase HR and decrease SV
- 25.Benzodiazepines are preferred as a pre-medication for anesthesia because they do not cause any respiratory depression in patients.
- A.
True
- B.
False
Questions: 25 | Attempts: 14844 | Last updated: Mar 22, 2022
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