Top 200 - Infectious Diseases 1a

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Top 200 - Infectious Diseases 1a - Quiz


Quiz on the first set of Top 200 ID drugs available. Includes Pencillins, Cephalosporins, and Macrolides.


Questions and Answers
  • 1. 

    Which of the following is the generic name for Veetids:

    • A.

      Amoxicillin/Clavulanate

    • B.

      Erythromycin

    • C.

      Penicillin

    • D.

      Ciprofloxacin

    • E.

      Chlorhexidine

    Correct Answer
    C. Penicillin
    Explanation
    Penicillin is the generic name for Veetids. Veetids is a brand name for a medication that contains the antibiotic penicillin. Penicillin is commonly prescribed to treat various bacterial infections. It works by inhibiting the growth of bacteria and preventing them from forming cell walls. Therefore, penicillin is the correct answer as it accurately represents the generic name for Veetids.

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  • 2. 

    The generic for Amoxil is?

    Correct Answer
    Explanation
    Amoxil is a brand name for the generic drug amoxicillin. The generic name of a drug refers to its active ingredient, which is the same regardless of the brand name. Therefore, the generic for Amoxil is amoxicillin.

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  • 3. 

    The brand for amoxicillin is?

    Correct Answer
  • 4. 

    Augment or Augmentin ES-600 has what in it?

    Correct Answer
    amoxicillin/clavulanate
    Explanation
    Augment or Augmentin ES-600 contains amoxicillin/clavulanate. Amoxicillin is an antibiotic that belongs to the penicillin group and is effective against a wide range of bacteria. Clavulanate is a beta-lactamase inhibitor that helps to prevent the breakdown of amoxicillin by certain bacteria, thereby enhancing its effectiveness. The combination of amoxicillin and clavulanate in Augmentin ES-600 provides a broader spectrum of activity against bacteria and helps to overcome resistance.

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  • 5. 

    Amoxicillin/clavulanate is also known as what?

    Correct Answer
    Augmentin
    Augmentin ES-600
    Explanation
    Amoxicillin/clavulanate is commonly known by the brand name Augmentin. Augmentin ES-600 is a specific formulation of Amoxicillin/clavulanate that is used for certain infections in children. Both Augmentin and Augmentin ES-600 contain the same active ingredients, but they may have different strengths or dosage forms. Therefore, both Augmentin and Augmentin ES-600 are alternative names for Amoxicillin/clavulanate.

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  • 6. 

    What do Penicillins do?

    Correct Answer
    inhibit bacterial cell wall synthesis by binding to penicillin binding proteins and inhibiting peptidoglycan synthesis
    Explanation
    Penicillins are a type of antibiotics that work by inhibiting bacterial cell wall synthesis. They achieve this by binding to specific proteins called penicillin binding proteins, which are essential for the formation of the bacterial cell wall. By binding to these proteins, penicillins prevent the synthesis of peptidoglycan, a key component of the cell wall. As a result, the bacterial cell wall becomes weak and fragile, leading to the death of the bacteria.

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  • 7. 

    Penicillin is active for what kind of bacteria?

    • A.

      Strep species

    • B.

      Staph species

    • C.

      Haemophilus species

    • D.

      Escherichia species

    • E.

      Proteus species

    Correct Answer(s)
    A. Strep species
    B. Staph species
    Explanation
    Penicillin is active against both Strep species and Staph species of bacteria. Strep species refer to bacteria belonging to the Streptococcus genus, which includes bacteria that cause various infections such as strep throat and skin infections. Staph species refer to bacteria belonging to the Staphylococcus genus, which includes bacteria that cause infections such as skin infections, pneumonia, and bloodstream infections. Penicillin works by inhibiting the synthesis of the bacterial cell wall, leading to bacterial death. Therefore, it is effective against both Strep and Staph species.

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  • 8. 

    Penicillin is active against:

    • A.

      Gram - bacilli

    • B.

      Gram + bacilli

    • C.

      Gram - cocci

    • D.

      Gram + cocci

    Correct Answer
    D. Gram + cocci
    Explanation
    Penicillin is effective against Gram + cocci because it targets the peptidoglycan layer in the cell wall of bacteria. Gram + cocci have a thick peptidoglycan layer, making them susceptible to penicillin. On the other hand, Gram - bacteria have an outer membrane that acts as a barrier, making them less susceptible to penicillin. Bacilli and cocci refer to the shape of bacteria, and the Gram staining technique is used to classify bacteria based on their cell wall composition.

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  • 9. 

    Penicillin is vulnerable to:

    Correct Answer
    penicillinase bacterial resistance
    Explanation
    Penicillin is vulnerable to penicillinase bacterial resistance. Penicillinase is an enzyme produced by certain bacteria that breaks down penicillin and renders it ineffective. This resistance mechanism is a common problem in the treatment of bacterial infections with penicillin, as it reduces the drug's effectiveness. Bacteria that produce penicillinase are able to survive and multiply even in the presence of penicillin, leading to treatment failure. Therefore, penicillinase bacterial resistance poses a significant challenge in the successful use of penicillin as an antibiotic.

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  • 10. 

    Penicillin is ineffective against:

    Correct Answer
    Staph aureus
    Explanation
    Penicillin is ineffective against Staph aureus because Staph aureus has developed resistance to penicillin. This resistance is primarily due to the production of an enzyme called penicillinase, which breaks down penicillin and renders it ineffective. As a result, penicillin cannot effectively target and kill Staph aureus bacteria, making it an ineffective treatment option for infections caused by this particular bacterium.

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  • 11. 

    Amoxicillin can act against what bacteria:

    Correct Answer
    Haemophilus influenzae, Escherichia coli, Proteus mirabilis
    Haemophilus influenzae
    Escherichia coli
    Proteus mirabilis
    Explanation
    Amoxicillin is an antibiotic that is effective against a wide range of bacteria. It can act against Haemophilus influenzae, Escherichia coli, and Proteus mirabilis. These bacteria are commonly associated with various infections in the body, and amoxicillin works by inhibiting the growth and multiplication of these bacteria. Therefore, it is an effective treatment option for infections caused by these specific bacteria.

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  • 12. 

    Amoxicillin is vulnerable to what?  And where are these found?

    Correct Answer
    beta-lactamase bacterial resistance in clinical isolates
    Explanation
    Amoxicillin is vulnerable to beta-lactamase bacterial resistance in clinical isolates. Beta-lactamase is an enzyme produced by certain bacteria that can break down the beta-lactam ring structure found in antibiotics like amoxicillin. This resistance mechanism allows the bacteria to inactivate the antibiotic and render it ineffective. Clinical isolates refer to bacteria that have been obtained from patients in a clinical setting, such as hospitals or clinics. Therefore, this resistance mechanism can be found in bacteria that have been isolated from patients in these settings.

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  • 13. 

    Clavulanate is what?

    Correct Answer
    beta-lactamase inhibitor
    Explanation
    Clavulanate is a beta-lactamase inhibitor. Beta-lactamase is an enzyme produced by certain bacteria that can break down and inactivate beta-lactam antibiotics, such as penicillins and cephalosporins. Clavulanate works by binding to and inhibiting the beta-lactamase enzyme, allowing the beta-lactam antibiotics to remain effective against the bacteria. This combination of clavulanate with a beta-lactam antibiotic is often used to treat bacterial infections caused by beta-lactamase-producing bacteria, enhancing the effectiveness of the antibiotic treatment.

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  • 14. 

    Clavulanate with amoxicillin does what?

    Correct Answer
    extends the activity of beta-lactamase producing strains of staph, H. flu, and E. coli
    Explanation
    Clavulanate with amoxicillin extends the activity of beta-lactamase producing strains of staph, H. flu, and E. coli. Beta-lactamase is an enzyme produced by certain bacteria that can inactivate antibiotics like amoxicillin. Clavulanate is a beta-lactamase inhibitor that prevents the inactivation of amoxicillin by binding to the enzyme. This combination therapy allows amoxicillin to remain effective against these strains of bacteria, increasing its activity and improving treatment outcomes.

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  • 15. 

    Penicillins are used for the indications of what locations (5 total)?

    Correct Answer
    respiratory tract, otitis media, sinusitis, skin, and urinary tract
    Explanation
    Penicillins are a class of antibiotics that are commonly used to treat various infections caused by bacteria. The indications listed in the answer - respiratory tract, otitis media, sinusitis, skin, and urinary tract - represent different locations in the body where these infections can occur. Penicillins are effective in treating respiratory tract infections such as pneumonia, bronchitis, and tonsillitis. They are also used to treat otitis media (middle ear infection), sinusitis (sinus infection), skin infections like cellulitis and impetigo, and urinary tract infections.

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  • 16. 

    Contraindications for Penicillins are?

    Correct Answer
    anaphylactic reaction to any penicillin
    Explanation
    The contraindications for Penicillins are anaphylactic reactions to any penicillin. This means that if a person has experienced a severe allergic reaction to any type of penicillin in the past, they should not take any form of penicillin medication. Anaphylactic reactions can be life-threatening and can include symptoms such as difficulty breathing, swelling of the face or throat, and a rapid drop in blood pressure. It is important for healthcare providers to be aware of a patient's allergy history and avoid prescribing penicillins to individuals with a known anaphylactic reaction to any penicillin.

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  • 17. 

    What do you do with Penicillin doses with renal impaired patients?

    Correct Answer
    adjust the dose
    Explanation
    In renal impaired patients, the kidneys are not functioning properly, which can affect the clearance of medications from the body. Since Penicillin is primarily eliminated through the kidneys, adjusting the dose is necessary to avoid the accumulation of the drug and potential toxicity. By adjusting the dose, healthcare professionals can ensure that the patient receives an appropriate amount of Penicillin that takes into account their impaired renal function. This helps to maintain therapeutic efficacy while minimizing the risk of adverse effects.

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  • 18. 

    All of the following are adverse reactions with Penicillins EXCEPT?

    • A.

      Mild diarrhea

    • B.

      Nausea

    • C.

      Headache

    • D.

      Thrush

    • E.

      Vaginal candidiasis

    Correct Answer
    C. Headache
    Explanation
    The question asks for an adverse reaction that is NOT associated with Penicillins. Headache is not commonly reported as an adverse reaction to Penicillins, unlike the other options listed. Mild diarrhea, nausea, thrush, and vaginal candidiasis are known adverse reactions that can occur with Penicillins. Therefore, the correct answer is headache.

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  • 19. 

    Which of the following are adverse reactions with Penicillins?

    • A.

      Headache

    • B.

      Nausea

    • C.

      Extreme diarrhea

    • D.

      Allergy-rash

    • E.

      Vaginal candidiasis

    Correct Answer(s)
    B. Nausea
    D. Allergy-rash
    E. Vaginal candidiasis
    Explanation
    Penicillins are a class of antibiotics that can cause certain adverse reactions. Nausea is a common side effect of taking penicillins, which can cause discomfort and an upset stomach. Allergy-rash is another adverse reaction that can occur with penicillins, where individuals may develop a rash or hives as an allergic response to the medication. Vaginal candidiasis, also known as a yeast infection, can also be a side effect of penicillin use, as the antibiotic can disrupt the natural balance of bacteria in the body, leading to an overgrowth of yeast in the vagina.

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  • 20. 

    Which of the following are adverse reactions with Penicillins?

    • A.

      Mild diarrhea

    • B.

      Nausea

    • C.

      Oral candidiasis

    • D.

      Vaginal candidiasis

    • E.

      Hives

    Correct Answer(s)
    A. Mild diarrhea
    B. Nausea
    C. Oral candidiasis
    D. Vaginal candidiasis
    E. Hives
    Explanation
    Penicillins can cause adverse reactions such as mild diarrhea, nausea, oral candidiasis, vaginal candidiasis, and hives. Mild diarrhea and nausea are common side effects of penicillin use. Oral candidiasis, also known as thrush, is a fungal infection that can occur in the mouth as a result of taking penicillins. Vaginal candidiasis, or yeast infection, may also develop in women using penicillins. Hives, or urticaria, are a type of skin rash that can be triggered by an allergic reaction to penicillins.

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  • 21. 

    Which of the following are rare adverse reactions with Penicillins?

    • A.

      Allergy-rash

    • B.

      Nausea

    • C.

      Hives

    • D.

      Thrush

    • E.

      Mild diarrhea

    Correct Answer(s)
    A. Allergy-rash
    C. Hives
    Explanation
    Penicillins are known to cause allergic reactions in some individuals, which can manifest as rashes or hives. These adverse reactions are considered rare because not everyone who takes penicillins will experience them. Nausea, thrush, and mild diarrhea are more common side effects of penicillins and are not considered rare.

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  • 22. 

    Which of the following are rare adverse reactions with Penicillins?

    • A.

      Yeast infection

    • B.

      Mild diarrhea

    • C.

      Shortness of breath

    • D.

      Nausea

    • E.

      Hives

    Correct Answer(s)
    C. Shortness of breath
    E. Hives
    Explanation
    Shortness of breath and hives are considered rare adverse reactions with Penicillins. While yeast infection, mild diarrhea, and nausea are more common side effects, shortness of breath and hives occur less frequently. These reactions may indicate an allergic reaction to the medication and should be reported to a healthcare professional immediately.

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  • 23. 

    Penicillins are eliminated through which process?

    • A.

      Urinary elimination

    • B.

      Renal elimination

    Correct Answer
    B. Renal elimination
    Explanation
    Penicillins are eliminated through renal elimination, which means they are excreted from the body through the kidneys. This process involves the filtration of penicillins from the blood into the urine by the kidneys. Renal elimination is an important route of elimination for many drugs, including penicillins, as it allows for the removal of these substances from the body and helps maintain drug levels within a therapeutic range.

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  • 24. 

    How should a patient be monitored when taking Penicillins?

    Correct Answer
    signs of anaphylaxis during first dose
    white blood cell count and febrile status
    baseline serum creatinine and blood urea nitrogen if renal impairment is suspected
    Explanation
    Patients taking Penicillins should be monitored for signs of anaphylaxis during the first dose. Anaphylaxis is a severe allergic reaction that can occur immediately after taking the medication. Monitoring for signs such as difficulty breathing, hives, swelling, and low blood pressure is important to ensure prompt medical intervention if needed. Additionally, monitoring the white blood cell count and febrile status can help detect any potential infections or adverse reactions to the medication. Lastly, baseline serum creatinine and blood urea nitrogen should be monitored if there is a suspicion of renal impairment, as Penicillins can affect kidney function.

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  • 25. 

    If renal impairment is suspected, how should a patient be monitored for Penicillins?

    Correct Answer
    baseline serum creatinine and blood urea nitrogen
    Explanation
    Patients should be monitored for Penicillins by obtaining baseline serum creatinine and blood urea nitrogen levels. This is because renal impairment can affect the excretion of Penicillins from the body, leading to potential toxicity. By measuring these parameters before starting Penicillin therapy, healthcare providers can assess the baseline kidney function and adjust the dosage accordingly to prevent any adverse effects. Regular monitoring of serum creatinine and blood urea nitrogen levels during treatment can help detect any changes in renal function and guide further management if necessary.

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  • 26. 

    What is increased when Penicillins are taken?

    Correct Answer
    oral contraceptive failure
    Explanation
    When Penicillins are taken, it can increase the risk of oral contraceptive failure. This is because Penicillins can affect the metabolism of hormones in the body, including those found in oral contraceptives. This can lead to a decrease in the effectiveness of the contraceptive and increase the chances of pregnancy. It is important for individuals taking Penicillins to use alternative methods of contraception or consult with their healthcare provider to ensure adequate protection against pregnancy.

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  • 27. 

    When Penicillins are taken what should women on oral contraceptives be told?

    Correct Answer
    there is an increased risk of contraceptive failure
    Explanation
    Women on oral contraceptives should be informed that taking Penicillins can potentially increase the risk of contraceptive failure. This is because Penicillins can interfere with the effectiveness of oral contraceptives, reducing their ability to prevent pregnancy. It is important for women to be aware of this potential interaction and to consider using additional methods of contraception, such as condoms, while taking Penicillins to ensure effective contraception.

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  • 28. 

    What is one drug-drug interaction with Penicillins?

    Correct Answer
    Explanation
    Penicillins can interact with oral contraceptives, reducing their effectiveness and increasing the risk of unintended pregnancy. This interaction occurs because penicillins can alter the gut flora, which in turn affects the metabolism of estrogen in oral contraceptives. It is recommended to use alternative or additional methods of contraception while taking penicillins to ensure effectiveness.

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  • 29. 

    How is Augmentin dosing based?

    Correct Answer
    amoxicillin component
    Explanation
    Augmentin dosing is based on the amoxicillin component. Augmentin is a combination antibiotic that contains amoxicillin and clavulanate potassium. The amoxicillin component is responsible for the antibacterial activity of the medication. The dosing of Augmentin is determined based on the specific condition being treated, the severity of the infection, and the patient's age and weight. The amoxicillin component plays a crucial role in determining the appropriate dosage of Augmentin to ensure effective treatment of bacterial infections.

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  • 30. 

    Which component of Augmentin determines the dosing?

    Correct Answer
    amoxicillin
    Explanation
    The dosing of Augmentin is determined by the component amoxicillin. Amoxicillin is an antibiotic that is commonly used to treat various bacterial infections. The dosage of Augmentin, which is a combination medication containing amoxicillin and clavulanate potassium, is based on the specific condition being treated, the severity of the infection, and the patient's age and weight. Amoxicillin is a crucial component in determining the appropriate dose of Augmentin to effectively treat the infection.

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  • 31. 

    Which of the following counseling highlights should be explained when taking Penicillins?

    • A.

      Take the entire course of medication.

    • B.

      Report mild diarrhea promptly.

    • C.

      Suspensions should be shaken before use.

    • D.

      There may be an increased risk of oral contraceptive failure.

    • E.

      Store tablets in the refrigerator.

    Correct Answer(s)
    A. Take the entire course of medication.
    C. Suspensions should be shaken before use.
    D. There may be an increased risk of oral contraceptive failure.
    Explanation
    When taking Penicillins, it is important to emphasize the following counseling highlights:

    1. Take the entire course of medication: This is crucial to ensure that the infection is completely treated and to prevent the development of antibiotic resistance.

    2. Suspensions should be shaken before use: Shaking the suspension ensures that the medication is evenly distributed, allowing for accurate dosing.

    3. There may be an increased risk of oral contraceptive failure: Penicillins can reduce the effectiveness of oral contraceptives, so it is important to use alternative methods of contraception during antibiotic treatment.

    These counseling points help ensure that the medication is taken correctly, potential drug interactions are addressed, and the efficacy of treatment is maximized.

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  • 32. 

    Which of the following counseling highlights should be explained when taking Penicillins?

    • A.

      Report severe diarrhea promptly.

    • B.

      Stop taking the medication when you feel better.

    • C.

      Suspensions should be taken at intervals around the clock.

    • D.

      Males should report symptoms of vaginitis

    • E.

      Store suspensions in the refrigerator

    Correct Answer(s)
    A. Report severe diarrhea promptly.
    C. Suspensions should be taken at intervals around the clock.
    E. Store suspensions in the refrigerator
    Explanation
    When taking Penicillins, it is important to report severe diarrhea promptly as it could be a sign of a serious side effect. Additionally, suspensions should be taken at intervals around the clock to maintain a consistent level of the medication in the body. Finally, it is advisable to store suspensions in the refrigerator to maintain their effectiveness.

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  • 33. 

    Which of the following counseling highlights should be explained when taking Penicillins?

    • A.

      Females should report symptoms of thrush.

    • B.

      May increase the effectiveness of oral contraceptives.

    • C.

      Suspensions should be stored at room temperature.

    • D.

      Take the entire medication regimen regardless of how they feel.

    • E.

      Report sever diarrhea promptly.

    Correct Answer(s)
    D. Take the entire medication regimen regardless of how they feel.
    E. Report sever diarrhea promptly.
    Explanation
    When taking Penicillins, it is important to emphasize the need to take the entire medication regimen, even if the individual starts feeling better. This is because stopping the medication prematurely can lead to the reoccurrence of the infection or the development of antibiotic resistance. Additionally, severe diarrhea should be reported promptly as it may be a sign of a serious side effect or a superinfection.

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  • 34. 

    Which of the following counseling highlights should be explained when taking Penicillins?

    • A.

      Suspensions should be shaken well before each dose.

    • B.

      Suspensions should be taken at intervals around-the-clock

    • C.

      Suspensions should be saved for later use once the patient feels better.

    • D.

      Suspensions should be stored in the refrigerator.

    • E.

      Suspensions may decrease the effectiveness of oral contraceptives.

    Correct Answer(s)
    A. Suspensions should be shaken well before each dose.
    B. Suspensions should be taken at intervals around-the-clock
    D. Suspensions should be stored in the refrigerator.
    E. Suspensions may decrease the effectiveness of oral contraceptives.
    Explanation
    The counseling highlights that should be explained when taking Penicillins include: suspensions should be shaken well before each dose to ensure proper mixing of the medication, suspensions should be taken at intervals around-the-clock to maintain a consistent level of the medication in the body, suspensions should be stored in the refrigerator to maintain their stability and effectiveness, and suspensions may decrease the effectiveness of oral contraceptives, so alternative methods of contraception should be considered.

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  • 35. 

    Which of the following counseling highlights should be explained when taking Penicillins?

    • A.

      Report severe diarrhea promptly.

    • B.

      Females should report symptoms of vaginitis

    • C.

      Entire medication course should be taken regardless of how the patient feels.

    • D.

      Suspensions should be stored in the refrigerator, shaken before each dose, and taken at intervals around the clock.

    • E.

      May decrease the effectiveness of oral contraceptives.

    Correct Answer(s)
    A. Report severe diarrhea promptly.
    B. Females should report symptoms of vaginitis
    C. Entire medication course should be taken regardless of how the patient feels.
    D. Suspensions should be stored in the refrigerator, shaken before each dose, and taken at intervals around the clock.
    E. May decrease the effectiveness of oral contraceptives.
    Explanation
    When taking Penicillins, it is important to report severe diarrhea promptly as it may indicate a serious side effect of the medication. Females should also report symptoms of vaginitis, as this could be a sign of a vaginal infection that may require treatment. It is crucial to complete the entire medication course, even if the patient starts feeling better, to ensure that the infection is fully treated and prevent antibiotic resistance. Suspensions should be stored in the refrigerator, shaken before each dose, and taken at intervals around the clock to maintain their effectiveness. Additionally, Penicillins may decrease the effectiveness of oral contraceptives, so alternative methods of contraception should be used during treatment.

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  • 36. 

    What is the generic for Keflex?

    Correct Answer(s)
    cephalexin
    Explanation
    The generic name for Keflex is cephalexin. Generic names are the official names given to drugs that are not protected by a brand name patent. Cephalexin is a type of antibiotic medication that is commonly used to treat various bacterial infections. It belongs to the class of drugs known as cephalosporins and works by stopping the growth of bacteria. By using the generic name, healthcare professionals and patients can easily identify and prescribe or purchase the correct medication.

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  • 37. 

    What is the brand for cephalexin?

    Correct Answer(s)
    Keflex
    Explanation
    Keflex is the brand name for cephalexin. This answer is correct because Keflex is a commonly known brand for cephalexin, which is an antibiotic medication used to treat various bacterial infections.

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  • 38. 

    What is the generic for Cefzil?

    Correct Answer(s)
    cefprozil
    Explanation
    Cefzil is a brand name for the generic drug cefprozil. Therefore, the correct answer is cefprozil.

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  • 39. 

    What is the brand for cefprozil?

    Correct Answer(s)
    Cefzil
    Explanation
    Cefzil is the brand name for cefprozil.

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  • 40. 

    What is the generic for Ceftin?

    Correct Answer(s)
    cefuroxime
    Explanation
    The generic name for Ceftin is cefuroxime. Ceftin is a brand name medication, and cefuroxime is the active ingredient in it. Generic drugs are equivalent to their brand name counterparts in terms of safety, effectiveness, and quality. Therefore, cefuroxime can be used as a cheaper alternative to Ceftin while providing the same therapeutic benefits.

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  • 41. 

    What is the brand for cefuroxime?

    Correct Answer(s)
    Ceftin
    Explanation
    Ceftin is the brand name for cefuroxime.

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  • 42. 

    What is the generic for Omnicef?

    Correct Answer(s)
    cefdinir
    Explanation
    The generic name for Omnicef is cefdinir.

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  • 43. 

    What is the brand for cefdinir?

    Correct Answer(s)
    Omnicef
    Explanation
    Omnicef is the brand name for cefdinir.

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  • 44. 

    What is the generic for Suprax?

    Correct Answer(s)
    cefixime
    Explanation
    The generic name for Suprax is cefixime.

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  • 45. 

    What is the brand for cefixime?

    Correct Answer(s)
    Suprax
    Explanation
    Suprax is the brand name for the medication cefixime. Cefixime is an antibiotic that is used to treat various bacterial infections. It works by stopping the growth of bacteria in the body. Suprax is available in the form of tablets or suspension and is commonly prescribed by healthcare professionals to treat conditions such as respiratory tract infections, urinary tract infections, and gonorrhea.

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  • 46. 

    What do Cephalosporins do?

    Correct Answer(s)
    inhibit bacterial cell wall synthesis by binding to penicillin binding proteins and inhibiting peptidoglycan synthesis
    Explanation
    Cephalosporins are a class of antibiotics that work by inhibiting bacterial cell wall synthesis. They achieve this by binding to penicillin binding proteins, which are enzymes involved in the formation of the bacterial cell wall, and inhibiting the synthesis of peptidoglycan, a major component of the cell wall. By disrupting the cell wall, cephalosporins weaken the bacteria and make them more susceptible to destruction by the immune system or other antibiotics.

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  • 47. 

    Cephalexin is what generation of Cephalosporins?

    Correct Answer(s)
    first generation
    Explanation
    Cephalexin belongs to the first generation of Cephalosporins. This generation of antibiotics was among the earliest developed and is effective against a wide range of gram-positive bacteria. First-generation Cephalosporins have a broad spectrum of activity, including coverage against Staphylococcus aureus and Streptococcus pneumoniae. They are commonly used for treating skin and soft tissue infections, respiratory tract infections, and urinary tract infections.

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  • 48. 

    Cephalexin is very active against what kind of bacteria?

    Correct Answer(s)
    gram + bacteria
    Explanation
    Cephalexin is very effective against gram-positive bacteria. Gram-positive bacteria have a thick layer of peptidoglycan in their cell walls, making them more susceptible to the action of cephalexin. This antibiotic works by inhibiting the synthesis of bacterial cell walls, leading to the destruction of the bacteria. Gram-positive bacteria include Staphylococcus, Streptococcus, and Enterococcus species, among others.

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  • 49. 

    Cephalexin is marginally active against what kind of bacteria?

    Correct Answer(s)
    gram - bacteria
    Explanation
    Cephalexin is marginally active against gram-negative bacteria. Gram-negative bacteria have a more complex cell wall structure compared to gram-positive bacteria, making them less susceptible to certain antibiotics. Cephalexin is a first-generation cephalosporin antibiotic that primarily targets gram-positive bacteria, but it also has limited activity against some gram-negative bacteria. However, it is generally less effective against gram-negative bacteria compared to other antibiotics specifically designed to target them.

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  • 50. 

    First Generation Cephalosporins are active with which of the following?

    • A.

      Enterococci

    • B.

      Staph. epidermidis

    • C.

      Methicillin-resistant Staph

    • D.

      All of the Above

    • E.

      None of the Above

    Correct Answer
    E. None of the Above
    Explanation
    First Generation Cephalosporins are not active against Enterococci, Staph. epidermidis, or Methicillin-resistant Staph. These antibiotics are primarily effective against gram-positive bacteria, including some strains of Staphylococcus aureus and Streptococcus pneumoniae. However, they do not have activity against Enterococci, which are gram-positive bacteria that are inherently resistant to first-generation cephalosporins. Staph. epidermidis and Methicillin-resistant Staph, which are both strains of Staphylococcus, are also resistant to first-generation cephalosporins due to the production of beta-lactamases. Therefore, the correct answer is None of the Above.

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