Schizophrenia- Disorder And Treatment

10 Questions | Total Attempts: 293

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Therapeutic Quizzes & Trivia

Pharmaco-Therapeutics Quiz for Schizophrenia


Questions and Answers
  • 1. 
    A patient MZ has recently been diagnosed with schizophrenia. His doctor wants to start him on a second generation antipsychotic that can be taken orally, but later switched over to an IV or IM formulation that is LONG ACTING, since MZ has had a history of non-compliance. The doc can't remember what options he has... you tell him:
    • A. 

      Geodon

    • B. 

      Zyprexa

    • C. 

      Risperdal

    • D. 

      Haldol

    • E. 

      All of the above

  • 2. 
    The two SGA's listed with the HIGHEST tendency to cause QT prolongation as a side effect are:
    • A. 

      Iloperidone and Ziprasidone

    • B. 

      Aripiprazole and Ziprasidone

    • C. 

      Aripiprazole and Thioridizine

    • D. 

      Iloperidone and Thioridizine

    • E. 

      Thioridizine and Ziprasidone

  • 3. 
    Which of the following are a BLACK BOX warning for clozapine
    • A. 

      Agranulocytosis

    • B. 

      Myocarditis

    • C. 

      Respiratory Depression

    • D. 

      A and C

    • E. 

      All of the above

  • 4. 
    A patient is taking clozapine for over a month at a dose of 200mg per day. WBC is being monitored weekly and today the patients WBC count is at 2550/mm^3. You suggest:
    • A. 

      Keep the patient going on the medication; the drop in WBC is expected

    • B. 

      Perform twice weekly WBC counts now

    • C. 

      Stop therapy until WBC counts go back above 3000 with no signs of infection

    • D. 

      A and B

    • E. 

      B and C

  • 5. 
    Which of the following are positive symptoms of schizophrenia?
    • A. 

      Hallucinations

    • B. 

      Anhedonia

    • C. 

      Poor hygeine/grooming

    • D. 

      Alogia

    • E. 

      None of the above

  • 6. 
    Choose the INCORRECT pair of EPS and its treatment:
    • A. 

      Acute dystonia- Benztropine IM

    • B. 

      Akathisia- Diphenhydramine PO

    • C. 

      Pseudoparkinsonism- Trihexyphenidyl PO

    • D. 

      Neuroleptic Malignant Syndrome- Bromocriptine and Dantroline

    • E. 

      All of the above are correct

  • 7. 
    Which is true of antipsychotics in the treatment of shizophrenia?
    • A. 

      A perfect drug would INCREASE dopamine in the Mesocortical pathway but DECREASE dopamine in the Mesolimbic pathway.

    • B. 

      FGA's tend to treat the positive symptoms of shizophrenia, while SGA's tend to treat both positive AND negative symptoms.

    • C. 

      FGA's differ from SGA's in the fact that SGA's have less incidence of EPS and better mood stabilizing properties.

    • D. 

      A common side effect of antipsychotics is that they decrease the seizure threshold.

    • E. 

      All of the above.

  • 8. 
    Select the true statement regarding FGAs.
    • A. 

      Haloperidol, a low potency agent, tends to have more EPS but less anticholinergic effects.

    • B. 

      Haloperidol, a high potency agent, tends to have more EPS but less anticholinergic effects.

    • C. 

      Chlorpromazine, a low potency agent, tends to have more EPS but less anticholinergic effects.

    • D. 

      Chlorpromazine, a high potency agent, tends to have more EPS but less anticholinergic effects.

  • 9. 
    When switching from oral Haldol to Haldol Depot injection:
    • A. 

      Oral medication should be tapered over 16 weeks.

    • B. 

      It is okay to start the depot formulation if the patient was not on oral haloperidol first.

    • C. 

      The depot injection dose given should be 10X the oral dose.

    • D. 

      None of the above.

    • E. 

      All of the above.

  • 10. 
    What is your favorite SGA and why?
    • A. 

      Clozapine because it's got so many black box warnings

    • B. 

      Ziprasidone because it has very few side effects besides its silly QT prolongation warnings

    • C. 

      Paliperidone because its brand name is so awesome: Invega Sustena

    • D. 

      Olanzapine because it makes people Fatties!

    • E. 

      All of the above