RHEUMATOID ARTHRITIS

2.

RA is characterized by

Symmetric synovitis
Joint erosion
Multisystem extra articular manifestations
All of the above
A&b only

Correct Answer

A. All of the above

Explanation

Rheumatoid arthritis (RA) is a chronic autoimmune disease that primarily affects the joints. It is characterized by symmetric synovitis, which means that the inflammation occurs in the same joints on both sides of the body. Joint erosion is another characteristic of RA, where the inflammation leads to the destruction of the joint cartilage and bone. Additionally, RA can also have multisystem extra articular manifestations, meaning that it can affect other parts of the body besides the joints, such as the skin, eyes, heart, and lungs. Therefore, the correct answer is "all of the above."

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2

3.

RA affects lumbar spine

True
False

Correct Answer

A. False

Explanation

It can affect the cervical spine, which in fact can result in paralysis due to C1-C2 subluxation with resultant spinal cord damage

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1

4.

Sulfasalazine is contrainidcated with

Sulfa intolerace
G6PD
Hypertension
All of the above
A&B
A&C

Correct Answer

A. A&B

Explanation

Sulfasalazine is contraindicated with sulfa intolerance and G6PD deficiency. This means that individuals who are allergic or intolerant to sulfa drugs should not take sulfasalazine, as it may cause severe allergic reactions. Additionally, individuals with G6PD deficiency should avoid sulfasalazine, as it can trigger hemolytic anemia in these individuals. Hypertension is not listed as a contraindication for sulfasalazine. Therefore, the correct answer is A&B, meaning that sulfasalazine is contraindicated with sulfa intolerance and G6PD deficiency.

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1

5.

Which cannot be taken in pregnancy

Methotrexate
Leflunomide
Both
None of the above

Correct Answer

A. Methotrexate

Explanation

Methotrexate cannot be taken during pregnancy because it is a medication that can cause harm to the developing fetus. Methotrexate is commonly used to treat conditions such as rheumatoid arthritis and certain types of cancer, but it is known to have teratogenic effects, meaning it can cause birth defects or pregnancy loss. Therefore, it is important for women to avoid taking methotrexate while pregnant or planning to become pregnant. Leflunomide, on the other hand, is also contraindicated during pregnancy due to its potential for harm to the fetus.

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0

6.

Which biologic DMARD is used as a first line for moderate to severe RA

Etanercept
Inliximab
Adalmumab

Correct Answer

A. Adalmumab

Explanation

Adalimumab is used as a first-line treatment for moderate to severe rheumatoid arthritis (RA). It is a biologic disease-modifying antirheumatic drug (DMARD) that works by targeting and inhibiting tumor necrosis factor-alpha (TNF-alpha), a protein involved in the inflammatory process of RA. Adalimumab helps reduce joint inflammation, pain, and swelling, and can slow down the progression of joint damage. It is considered an effective and safe option for treating RA, and is often prescribed as part of a comprehensive treatment plan for managing the disease.

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1

7.

Biologic DMARDS are known for having Adverse effects such as

Infections
CHF
Hypertension
All of the above
A&b only
B&c only

Correct Answer

A. A&b only

Explanation

Biologic DMARDs are known to have adverse effects such as infections and CHF (congestive heart failure). This means that these medications can increase the risk of developing infections and can also potentially lead to heart failure. Hypertension (high blood pressure) is not specifically mentioned as an adverse effect of biologic DMARDs, so it is not included in the answer. Therefore, the correct answer is a&b only.

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Rheumatoid Arthritis

How much of the population is affected by RA?

Quiz Preview

RA is characterized by

RA affects lumbar spine

Sulfasalazine is contrainidcated with

Which cannot be taken in pregnancy

Which biologic DMARD is used as a first line for moderate to severe RA

Biologic DMARDS are known for having Adverse effects such as