2.
Powdered drugs compressed into pills or disks
Explanation
The given answer "Tablet, Tablets" is the correct answer because powdered drugs are often compressed into pills or disks, which are commonly known as tablets. Tablets are a common form of medication that are easy to consume and transport. Therefore, the answer accurately describes the process of compressing powdered drugs into pills or disks.
3.
Powdered drugs enclosed within a gelatin coat.
Explanation
Capsules are a type of pharmaceutical dosage form that consists of powdered drugs enclosed within a gelatin coat. They are commonly used to administer medications orally. The gelatin coating helps to protect the drug from degradation and allows for easier swallowing. Capsules can come in different sizes and can be filled with a single drug or a combination of drugs. They are often used when the drug substance is not easily compressed into a solid tablet form or when multiple drugs need to be combined in a single dose.
4.
Most drugs that are oil-based or have suspended particles should not be given IV.
Explanation
Oil-based drugs or drugs with suspended particles should not be given intravenously because they can cause blockages in the blood vessels, leading to serious complications such as embolism or organ damage. Intravenous administration is typically reserved for drugs that are water-based and can be easily dissolved in the bloodstream. Giving oil-based or particle-containing drugs intravenously can be potentially life-threatening and should be avoided.
5.
The greater the blood supply to an area, the slower the drug is absorbed.
Explanation
The faster the drug is absorbed.
6.
Drug suspended in liquid that tends to settle out if left standing.
Correct Answer
Suspension
Explanation
A suspension is a drug that is mixed with a liquid but tends to settle out if left standing. In a suspension, the drug particles are dispersed throughout the liquid but are not completely dissolved. This causes the drug particles to settle at the bottom of the container over time. To use a suspension, it needs to be shaken or mixed before administration to ensure an even distribution of the drug particles in the liquid.
7.
The main site of biotransformation is
Explanation
The liver is the main site of biotransformation. Biotransformation refers to the process by which the body metabolizes or transforms various substances, such as drugs or toxins, into different forms that can be easily eliminated from the body. The liver plays a crucial role in this process as it contains enzymes that are responsible for breaking down and modifying these substances. This allows for their elimination through urine or bile. The kidneys and heart are not primarily involved in biotransformation, and Speedo is not a relevant organ in this context.
8.
1 gm = ______ mg
Correct Answer
1000
Explanation
The conversion factor between grams and milligrams is 1000. This means that 1 gram is equal to 1000 milligrams.
9.
Generic drugs are not the same as the original drug.
Explanation
Generic drugs are actually the same as the original drug in terms of active ingredients, dosage, strength, route of administration, and intended use. The only difference is that generic drugs are typically cheaper because they are produced by different manufacturers after the patent for the original drug has expired. The generic version must meet the same quality and safety standards as the original drug, making it a suitable alternative for many patients. Therefore, the statement "Generic drugs are not the same as the original drug" is false.
10.
The _____________ is the amount of time it takes for the amount of the drug to be reduced by one-half.
Correct Answer
Half-life
Half life
Explanation
The term "half-life" refers to the amount of time it takes for the concentration of a drug to decrease by half in the body. This is an important concept in pharmacology as it helps determine the dosing frequency and duration of a medication. Understanding the half-life of a drug can also provide insights into its elimination from the body and potential drug interactions.
11.
This route of administration is not usually performed. Accidental administration by this route can be fatal.
Correct Answer
A. Intra-arterial
Explanation
Intra-arterial administration refers to the delivery of a substance directly into an artery. This route is not commonly used due to its invasive nature and potential risks. Accidental administration by this route can be fatal because it bypasses the body's natural defense mechanisms and can lead to severe complications such as embolism or tissue damage. Therefore, it is important to avoid administering substances intra-arterially unless it is specifically intended and performed by trained medical professionals.
12.
_____________ drugs are placed on the skin or mucous membranes.
Correct Answer
Topical
Explanation
Topical drugs are applied directly on the skin or mucous membranes. They are designed to act locally and are absorbed into the tissues to provide relief or treatment for various conditions such as skin infections, inflammation, or pain. These drugs are available in various forms such as creams, ointments, gels, or patches, and are commonly used for dermatological conditions, wound healing, or local pain management. Applying drugs topically allows for targeted treatment and avoids potential side effects associated with systemic absorption.
13.
Enteric-coated and solution drugs are not common.
Explanation
Enteric-coated and sustained release forms are not common.
14.
__________ injections deliver drugs into the dermis of the skin.
Correct Answer
ID
Intradermal
Explanation
Intradermal injections deliver drugs into the dermis of the skin. The abbreviation "ID" stands for "Intradermal," which refers to the administration of medication into the layer of skin just below the epidermis. This type of injection is commonly used for diagnostic tests, such as tuberculosis screening or allergy testing, as well as for certain vaccinations. By delivering the drug directly into the dermis, intradermal injections allow for efficient absorption and distribution of the medication throughout the body.
15.
Generic drugs are usually much cheaper than the "name brand" drug.
Explanation
Generic drugs are typically less expensive than brand-name drugs because they are not marketed or advertised as heavily as brand-name drugs. Generic drugs are copies of brand-name drugs that have the same active ingredients, dosage, strength, and intended use. They are approved by the FDA and must meet the same quality and safety standards as brand-name drugs. The lower cost of generic drugs is due to the fact that generic manufacturers do not have to invest in research and development or the extensive marketing campaigns associated with brand-name drugs.
16.
Some drugs are given at a high dose to begin with, followed by smaller amounts to replace what the body has eliminated. The initial high dose is called the __________ dose.
Correct Answer
Loading
Explanation
In pharmacology, the term "loading dose" refers to the initial high dose of a drug that is administered to quickly achieve a therapeutic level in the body. This loading dose is often followed by smaller maintenance doses to replace the drug that has been eliminated by the body. The purpose of the loading dose is to rapidly establish the desired drug concentration in the body, especially when immediate therapeutic effects are required.
17.
The dose of the drug that is lethal to 50% of patients in a trial.
Correct Answer
LD50
Explanation
LD50 stands for "Lethal Dose 50," which refers to the dose of a drug that is lethal to 50% of patients in a trial. This measurement is commonly used in toxicology studies to determine the toxicity or lethality of a substance. LD50 provides valuable information about the potential harm or risk associated with a drug, helping researchers and regulators assess its safety profile.
18.
It is the LVT's responsibility to administer and chart the medication.
Explanation
The given statement is true. The responsibility of administering and charting medication lies with the LVT (Licensed Veterinary Technician). LVTs are trained professionals who have the knowledge and skills to safely administer medications to animals and accurately record the details of the medication given in the medical charts. This ensures proper documentation and monitoring of the animal's medication history, helping to provide effective and appropriate healthcare.
19.
An ________ drug reaction is an undesirable response to a drug and can be mild to life threatening.
Correct Answer
adverse
Explanation
An adverse drug reaction refers to any negative or undesirable response that occurs after taking a medication. These reactions can range from mild side effects to severe and life-threatening complications. Therefore, the term "adverse" accurately describes the nature of the reaction, highlighting its undesirability and potential harm.
20.
The patient's five rights include:
Correct Answer(s)
A. Right drug
A. Right time
A. Right dose
A. Right route
A. Right patient
Explanation
The patient's five rights refer to the essential elements that must be ensured when administering medication. These include giving the right drug, at the right time, in the right dose, through the right route, and to the right patient. These rights are crucial to prevent medication errors and ensure patient safety.
21.
_____________ is splitting the drug and adding a H2O molecule to the split products.
Correct Answer(s)
Hydrolysis
Explanation
Hydrolysis is a chemical reaction in which a compound is broken down by the addition of water molecules. In the context of the given question, hydrolysis is the process of splitting a drug molecule and adding a water molecule to the resulting products. This reaction can be important in pharmacology and drug metabolism, as it can lead to the breakdown of drugs into smaller, more easily excreted compounds.
22.
The amount of drug given at one time (in units of mass g, mg).
Correct Answer(s)
Dose
Explanation
The term "dose" refers to the amount of a drug that is given to an individual at one time. It is typically measured in units of mass, such as grams (g) or milligrams (mg). The dose is an important factor in determining the effectiveness and safety of a medication, as it determines the concentration of the drug in the body. The correct answer is "dose".
23.
________________________ are circumstances when drugs should not be used.
Correct Answer(s)
Contraindications
Explanation
Contraindications refer to specific circumstances or conditions in which the use of drugs is not recommended or should be avoided. These contraindications could be based on factors such as the patient's medical history, current health status, or potential adverse effects of the drug. It is important to identify contraindications before prescribing or administering medication to ensure patient safety and prevent any potential harm or complications.
24.
The series of events that occur after a drug has been administered including absorption and distribution are known as _______________________.
Correct Answer(s)
Pharmacokinetics
Explanation
Pharmacokinetics refers to the series of events that take place after a drug has been administered, including absorption and distribution. It involves the study of how drugs are absorbed, distributed, metabolized, and eliminated by the body. Understanding pharmacokinetics is important in determining the dosage and frequency of drug administration to achieve the desired therapeutic effect.
25.
1 tsp = ____ ml
Correct Answer(s)
5
Explanation
The given answer is correct because 1 teaspoon (tsp) is equal to 5 milliliters (ml).
26.
The dose of the drug that produces the desired effect in 50% of the patients in a trial.
Correct Answer(s)
ED50
Explanation
ED50 stands for Effective Dose 50, which refers to the dose of a drug that produces the desired effect in 50% of the patients in a clinical trial. This means that half of the patients in the trial experienced the desired effect when given this particular dose of the drug. ED50 is commonly used in pharmacology and clinical research to determine the optimal dosage for a drug to achieve the desired therapeutic effect in a population.
27.
___________________ is the body's ability to change a drug chemically from the form in which it was administered into a form that can be eliminated from the body.
Correct Answer(s)
Biotransformation
Metabolism
Explanation
Biotransformation, also known as metabolism, refers to the body's ability to chemically change a drug from its administered form into a form that can be eliminated from the body. This process involves various enzymatic reactions that convert the drug into metabolites, which are then excreted through urine or feces. Biotransformation is an essential process in drug elimination and helps to detoxify and remove drugs from the body.
28.
NEVER, NEVER, NEVER give ampicillin IV.
29.
Used as a last resort if other areas are not available.
Explanation
The given sequence is a combination of two-letter codes. Each code represents a specific area or location. The correct answer, "IP," suggests that it is used as a last resort if other areas are not available. This implies that IP is likely a code for a backup or alternative location that is utilized when other options are unavailable.
30.
A drug that has been transformed is called a
Correct Answer
metabolite
Explanation
A drug that has been transformed is called a metabolite. Metabolites are the products that result from the metabolism of a drug in the body. When a drug is metabolized, it undergoes various chemical reactions that break it down into different compounds, known as metabolites. These metabolites may have different pharmacological properties compared to the original drug, and they can be further processed and eliminated from the body. Therefore, metabolites play a crucial role in drug metabolism and are important for understanding the effects and fate of drugs in the body.
31.
The unique name given to a drug by the company that develops it is known as the ___________________.
Correct Answer
Trade name
Explanation
The unique name given to a drug by the company that develops it is known as the trade name. This name is used for marketing and branding purposes and is typically registered as a trademark. It helps to distinguish the drug from other similar products in the market and is often easier to remember and recognize for healthcare professionals and consumers. The trade name is different from the generic name, which is the common name of the drug based on its chemical composition.
32.
Solutions of drugs with water and sugar.
Correct Answer
Syrup
Syrups
Explanation
The correct answer is Syrup or Syrups because the question mentions "solutions of drugs with water and sugar." Syrups are commonly used to administer medication, where drugs are dissolved in water and mixed with sugar to make them more palatable. Syrups are thick, viscous liquids that are easy to swallow and often used for children or individuals who have difficulty swallowing pills. Therefore, Syrup or Syrups is the appropriate answer.
33.
TB or allergy testing uses which of the following routes:
Explanation
TB or allergy testing uses the ID (intradermal) route. This involves injecting a small amount of the test substance just under the skin. This allows for a localized reaction to occur, which can help determine if the individual is allergic to the substance or if they have been exposed to tuberculosis. Other routes such as IM (intramuscular), SQ (subcutaneous), and IP (intraperitoneal) are not typically used for TB or allergy testing.
34.
____________ is a loss of electrons.
Correct Answer
Oxidation
Explanation
Oxidation is a chemical process in which a substance loses electrons. This loss of electrons results in an increase in the oxidation state of the substance. Therefore, oxidation can be described as a loss of electrons.
35.
Drugs/metabolites do not pass directly into the milk of the mammary glands.
Explanation
Yes, they do.
36.
_______________ of a drug is why the drug is being used.
Correct Answer
Indication
Explanation
The term "indication" refers to the specific reason or purpose for which a drug is being used. It provides information about the medical condition or symptoms that the drug is intended to treat or manage. Understanding the indication of a drug is crucial for healthcare professionals to ensure appropriate and effective use of the medication. It helps guide the decision-making process when prescribing or administering drugs to patients.
37.
In books, the generic name usually starts with an uppercase letter (Ketamine), while the trade name starts with a lowercase letter (ketaject).
Explanation
Generic is lowercase, trade name is uppercase.
38.
Drugs that do not have a high toxicity and do not require a prescription are called _____________________ drugs.
Correct Answer
Over-the-counter
Over the counter
Explanation
Over-the-counter drugs are medications that are safe to use without a prescription from a healthcare professional. These drugs have low toxicity levels, meaning they are not harmful when taken in recommended doses. They are readily available for purchase at pharmacies, supermarkets, and other retail stores without the need for a prescription. The terms "over-the-counter" and "over the counter" are both correct ways to refer to these types of drugs.
39.
_____________ is a gain of electrons
Correct Answer
Reduction
Explanation
Reduction is a process in which a substance gains electrons. This can occur when a molecule or ion accepts electrons from another molecule or ion. The reduction process leads to a decrease in the oxidation state of the substance and is often accompanied by a gain of negative charge. In chemical reactions, reduction is typically paired with oxidation, which involves the loss of electrons. Together, these processes are known as redox reactions. Therefore, the given correct answer, "Reduction," accurately describes the gain of electrons.
40.
1 tbl = ______ ml
Correct Answer
15
Explanation
The question is asking for the conversion of 1 tablespoon (tbl) to milliliters (ml). The correct answer is 15 ml, as 1 tablespoon is equal to 15 milliliters.
41.
Which of the following routes of administration have the shortest duration?
Correct Answer
A. Intravenous
Explanation
Intravenous administration involves directly injecting a substance into the veins, allowing for rapid absorption and immediate effect. This route bypasses the digestive system, avoiding the time required for absorption and metabolism. Therefore, drugs administered intravenously have the shortest duration compared to other routes such as oral, intramuscular, or subcutaneous, which may involve slower absorption and metabolism processes.
42.
High potential for abuse: may lead to severe physical or psychological dependence (morphine, cocaine, pentobarbital).
Explanation
The correct answer is CII. This classification is given to drugs that have a high potential for abuse and may lead to severe physical or psychological dependence. Examples of drugs in this category include morphine, cocaine, and pentobarbital.
43.
______ medication is placed into the oral cavity or by a nasogastric or orogastric tube to the stomach.
Correct Answer
Oral
Explanation
The correct answer is "Oral" because it refers to the administration of medication through the mouth, either by swallowing it or by placing it directly into the oral cavity. This route of administration allows the medication to be absorbed through the gastrointestinal tract and enter the bloodstream. It is a common and convenient method of medication administration.
44.
Which of the following routes of administration usually last the longest?
Explanation
Oral administration usually lasts the longest compared to other routes of administration. This is because when a medication is taken orally, it has to go through the digestive system, where it is absorbed into the bloodstream. This process can take some time, resulting in a slower onset of action and a longer duration of effect. In contrast, intravenous, intramuscular, and subcutaneous routes of administration deliver medications directly into the bloodstream or muscle tissue, resulting in a faster onset of action but a shorter duration of effect.
45.
Drugs that block receptors (from other drugs or hormones) are called
Correct Answer
Antagonists
Explanation
Antagonists are drugs that block receptors, whether they are blocking the action of other drugs or hormones. They work by binding to the receptors and preventing the natural substances from binding and activating them. This inhibition of receptor activation can have various effects on the body, such as blocking the effects of certain hormones or other drugs. Therefore, the correct answer is Antagonists.
46.
1 kg = ______ g or ______ lbs. (include a comma between answers)
Correct Answer
1000, 2.2
Explanation
The conversion factor for kilograms to grams is 1000, which means that 1 kilogram is equal to 1000 grams. The conversion factor for kilograms to pounds is 2.2, which means that 1 kilogram is equal to 2.2 pounds.
47.
______________ administration delivers drugs through the skin. The most common application is of Fentanyl.
Correct Answer
Transdermal
Explanation
Transdermal administration refers to the delivery of drugs through the skin. This method allows the drug to be absorbed directly into the bloodstream, bypassing the digestive system. Fentanyl is a commonly used drug that is administered transdermally. It is typically delivered through a patch that is applied to the skin, allowing for slow and controlled release of the medication over a period of time. This route of administration is often used for drugs that need to be delivered continuously or for long-term treatment.
48.
Species, pH of drug, solubility of drug, size and shape of drug molecule, presence or absence of food in the GI tract, and degree of GI motility/disease process are all factors that determine the ____________ of a drug.
Correct Answer
Absorption
Explanation
The factors listed in the question, such as species, pH of the drug, solubility of the drug, size and shape of the drug molecule, presence or absence of food in the GI tract, and degree of GI motility/disease process, all contribute to the process of drug absorption. These factors affect how well and how quickly a drug is absorbed into the bloodstream after administration. Therefore, the correct answer is absorption.
49.
The degree to which drugs are absorbed and reach general circulation is called ____________________.
Correct Answer
Bioavailability
Explanation
Bioavailability refers to the extent to which a drug is absorbed into the bloodstream and reaches the general circulation. It indicates the fraction of the administered dose that actually reaches the systemic circulation and is available to produce a pharmacological effect. Factors such as the route of administration, drug formulation, and metabolism can affect the bioavailability of a drug.