Pharmacology - Cardiovascular SySTEM

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Quizzes Created: 1 | Total Attempts: 358
Questions: 6 | Attempts: 358

Cardiovascular System Quizzes & Trivia

Study Guide Quiz for Pharmacology - Need for Oxygen-Cardiovascular System

Questions and Answers
  • 1. 

    Initial metabolism in liver of a drug absorbed from GI tract before the drug reaches circulation in blood stream

    The first-pass effect refers to the initial metabolism that a drug undergoes in the liver after it is absorbed from the gastrointestinal tract. This metabolism occurs before the drug enters the systemic circulation and reaches the bloodstream. During the first-pass effect, enzymes in the liver can metabolize the drug, leading to a decrease in its concentration and potentially altering its pharmacological effects. This phenomenon is important to consider when determining the dosage and administration of drugs, as it can affect their bioavailability and therapeutic efficacy.

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  • 2. 

    Time required for half of a dose of a drug to be eliminated from the body or reduced by 50% in blood levels

    Half-life refers to the time required for half of a dose of a drug to be eliminated from the body or reduced by 50% in blood levels. In other words, it is the time it takes for the concentration of the drug in the body to decrease by half. This is an important pharmacokinetic parameter as it helps determine the dosing frequency and the rate at which the drug is cleared from the body. A shorter half-life means the drug is eliminated more quickly, while a longer half-life indicates a slower elimination rate.

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  • 3. 

    The process by which a drug enters the body and is available for therapeutic activity

    Absorption refers to the process by which a drug enters the body and becomes available for therapeutic activity. This process typically occurs after the drug is administered through various routes such as oral ingestion, injection, or inhalation. Once the drug is absorbed into the bloodstream, it can then be distributed to its target site and exert its intended therapeutic effects. Absorption plays a crucial role in determining the onset, intensity, and duration of a drug's action, making it an essential pharmacokinetic parameter to consider in drug development and clinical practice.

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  • 4. 

    The process, act or function of discharging or ejecting waste product of metabolism, especially from the system of an organism.

    Excretion refers to the process of eliminating waste products of metabolism from an organism's system. This can include the removal of waste materials such as urine, feces, and sweat. It is an essential process for maintaining the overall health and balance of the organism. Through excretion, harmful substances and excess substances are removed from the body, allowing for proper functioning and homeostasis.

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  • 5. 

    Length of time the concentration of a drug in the blood or tissue is sufficeint to elicit a response

    The duration of action refers to the length of time that the concentration of a drug in the blood or tissue is sufficient to elicit a response. This means that the drug remains active in the body and continues to produce its intended effects for a certain period of time. The duration of action can vary depending on factors such as the specific drug, its dosage, and individual variations in metabolism and excretion. Understanding the duration of action is important in determining the dosing frequency and overall effectiveness of a drug.

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  • 6. 

    One or more biochemical reactions involving a parent drug, occurs in the liver,  and produces a metabolite either active or inactive 

    Biotransformation refers to the process in which one or more biochemical reactions take place in the liver involving a parent drug, resulting in the production of a metabolite. This metabolite can either be active, meaning it still has pharmacological effects, or inactive, meaning it has lost its pharmacological activity. Biotransformation is an important process as it can affect the drug's efficacy, toxicity, and duration of action in the body.

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  • Mar 21, 2023
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