Nausea And Vomiting Quiz

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  • 1/52 Questions

    Which 5HT-3 receptor antagonist is used for acute AND delayed N/V?

    • Ondansetron
    • Palonsetron
    • Granisetron
    • Dolasetron
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About This Quiz

Explore the management of nausea and vomiting in this quiz, focusing on anti-emetic drugs like 5HT-3 receptor antagonists and NK1RA. Learn about drug interactions, appropriate dosages, and the neurotransmitters involved, essential for healthcare professionals dealing with chemotherapy patients.

Nausea And Vomiting Quiz - Quiz

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  • 2. 

    Which dose is correct when used in combination with aprepitant?

    • Ondansetron 32mg IV

    • Dexamethasone 12mg IV

    • Dexamethasone 20mg IV

    • Palonsetron 0.5mg IV

    Correct Answer
    A. Dexamethasone 12mg IV
    Explanation
    Ondansetron 32mg can cause QT prolongation. This is the correct dosing for dexamethasone in combo with any NK1RA.

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  • 3. 

    Which neurotransmitter does NK1RA (Neurokinin-1 Receptor Antagonist) affect?

    • Substance P

    • Dopamine

    • GABA

    • Serotonin

    Correct Answer
    A. Substance P
    Explanation
    NK1RAs block binding of Substance P in the CNS and GI to treat N/V.

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  • 4. 

    Acute N/V occurs within the first...

    • 24 hours

    • 6 hours

    • 48 hours

    • 12 hours

    Correct Answer
    A. 24 hours
    Explanation
    Acute N/V (nausea and vomiting) refers to the sudden onset of these symptoms. The correct answer, 24 hours, suggests that acute N/V typically occurs within the first day after a triggering event or condition. This timeframe aligns with common causes of acute N/V such as food poisoning, viral gastroenteritis, or adverse reactions to medications. It is important to note that this is a general guideline and individual experiences may vary.

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  • 5. 

    Which drugs cause significant delayed N/V? (select all that apply)

    • Carboplatin

    • Cyclophosphamide

    • Cisplatin

    • Doxorubicin

    • Vincristine

    • Etoposide

    Correct Answer(s)
    A. Carboplatin
    A. Cyclophosphamide
    A. Cisplatin
    Explanation
    Carboplatin, cyclophosphamide, and cisplatin are known to cause significant delayed nausea and vomiting (N/V) as side effects. These drugs are commonly used in chemotherapy treatments for various types of cancer. The delayed onset of N/V can occur several hours to days after the administration of these drugs and can significantly impact the patient's quality of life. Doxorubicin, vincristine, and etoposide, on the other hand, are not typically associated with significant delayed N/V.

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  • 6. 

    Which NK1RA does NOT inhibit CYP3A4?

    • Rolapitant

    • Netupitant

    • Aprepitant

    • All inhibit CYP3A4

    Correct Answer
    A. Rolapitant
    Explanation
    This drug also has a long half life (180 hours)!

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  • 7. 

    Which drug causes severe extravasation reactions?

    • Promethazine

    • Metoclopramide

    • Aprepitant

    • Haloperidol

    Correct Answer
    A. Promethazine
    Explanation
    Must dilute with 10mL NS if giving IV. Try to use oral if possible.

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  • 8. 

    Which is correct dosing (Highly Emetogenic Cheotherapy) HEC?

    • Zofran 16mg IV, Dexamethasone 20mg IV, Fosaprepitant 150mg IV

    • Zofran 32mg IV, Dexamethasone 20mg IV, Olanzapine 10mg PO

    • Aloxi 0.25mg IV, Dexamethasone 12mg IV, Olanzapine 10mg PO

    • Zofran 16mg PO, Dexamethasone 12mg PO, Aprepitant 125mg PO

    Correct Answer
    A. Zofran 16mg PO, Dexamethasone 12mg PO, Aprepitant 125mg PO
    Explanation
    Zofran 32 mg is too high. Dexamethasone when used with an NK1RA, the dose needs to be 12mg.

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  • 9. 

    Neurotransmitters involved in N/V include: (select all that apply)

    • Dopamine

    • Histamine

    • Endorphins

    • Serotonin

    • Acetylcholine

    • Substance P

    • GABA

    • Norepinephrine

    • Glutamate

    Correct Answer(s)
    A. Dopamine
    A. Histamine
    A. Endorphins
    A. Serotonin
    A. Acetylcholine
    A. Substance P
    A. GABA
    Explanation
    The neurotransmitters involved in N/V (nausea/vomiting) include dopamine, histamine, endorphins, serotonin, acetylcholine, substance P, and GABA. Nausea and vomiting can be caused by a variety of factors, including imbalances in these neurotransmitters. Dopamine, histamine, serotonin, and substance P are known to play a role in the chemoreceptor trigger zone (CTZ) in the brain, which is responsible for initiating the vomiting reflex. Endorphins, acetylcholine, and GABA can also contribute to nausea and vomiting by affecting the gastrointestinal tract and the central nervous system. Norepinephrine and glutamate are not typically associated with N/V.

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  • 10. 

    Risk factors for Chemotherapy Induced Nausea and Vomiting (CINV) include:

    • Age < 50

    • Females

    • Males

    • Infrequent alcohol use

    • Frequent alcohol use

    • History of motion sickness

    • Prior exposure to chemotherapy

    • No previous exposure to chemotherapy

    Correct Answer(s)
    A. Age < 50
    A. Females
    A. Infrequent alcohol use
    A. History of motion sickness
    A. Prior exposure to chemotherapy
    Explanation
    The risk factors for Chemotherapy Induced Nausea and Vomiting (CINV) include being under the age of 50, being female, having infrequent alcohol use, having a history of motion sickness, and having prior exposure to chemotherapy. These factors have been found to increase the likelihood of experiencing nausea and vomiting as a side effect of chemotherapy treatment.

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  • 11. 

    What is the correct dosing and route for Dolasetron for CINV?

    • 100mg PO

    • 100mg IV

    • 100mg topically

    • 50mg PO

    Correct Answer
    A. 100mg PO
    Explanation
    Dolasetron is only available PO.

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  • 12. 

    What is the correct dosing and route for Granisetron for CINV? (select all that apply)

    • 2mg PO

    • 1mg IV

    • 3.1mg/hr topically (patch)

    • 1mg/hr topically (patch)

    • 2mg IV

    • 1mg PO

    Correct Answer(s)
    A. 2mg PO
    A. 1mg IV
    A. 3.1mg/hr topically (patch)
    Explanation
    Granisetron is a medication commonly used for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). The correct dosing and route for Granisetron for CINV are as follows: 2mg PO (oral administration), 1mg IV (intravenous administration), and 3.1mg/hr topically (patch). These routes and doses are appropriate for managing CINV and can provide effective relief for patients undergoing chemotherapy.

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  • 13. 

    What is the correct dosing and route for Ondansetron for CINV? (select all that apply)

    • 16-24mg PO

    • 8-16mg IV

    • 4-8mg IV

    • 4-8mg PO

    Correct Answer(s)
    A. 16-24mg PO
    A. 8-16mg IV
    Explanation
    A way to help you remember: IV starts at 8 and you add 8 for the max (16). PO starts at the max of IV (16) and you add 8 again for the max (24)

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  • 14. 

    What is the correct dosing and route for Palonsetron for CINV?

    • 0.25mg IV

    • 0.25mg PO

    • 25mg IV

    • 25mg PO

    Correct Answer
    A. 0.25mg IV
    Explanation
    The PO dosing of Palonsetron is in a combo product.

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  • 15. 

    5-HT3 antagonists are effective for delayed CINV (Chemotherapy Induced Nausea and Vomiting).

    • True

    • False

    Correct Answer
    A. False
    Explanation
    They are effective for acute CINV, with the exception of Palonsetron which is effective for both acute and delayed CINV.

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  • 16. 

    5-HT3 antagonist work by blocking enterochromaffin cells in the GI and blocking serotonin receptors in the medulla.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    5-HT3 antagonists are a class of drugs that work by blocking the action of serotonin (5-HT3) receptors. These receptors are found in both the gastrointestinal (GI) tract and the medulla, which is a part of the brainstem. By blocking these receptors, 5-HT3 antagonists can prevent the activation of enterochromaffin cells in the GI tract, which are involved in the release of serotonin. Additionally, blocking serotonin receptors in the medulla can help to reduce nausea and vomiting, making 5-HT3 antagonists useful in the treatment of these symptoms. Therefore, the statement that 5-HT3 antagonists work by blocking enterochromaffin cells in the GI and blocking serotonin receptors in the medulla is true.

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  • 17. 

    Increasing the dose of a 5-HT3 antagonist will always increase the antiemetic effect but will also increase the side effects.

    • True

    • False

    Correct Answer
    A. False
    Explanation
    The receptors that 5-HT3 antagonists work on will eventually become saturated and the response will plateau and you will not get any greater response with increasing the dose. You will however increase the side effects risk.

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  • 18. 

    IV 5HT-3 antagonists should be given ____ prior to chemo, while PO should be given ____ prior to chemo.

    • 30; 60

    • 60; 30

    • 10; 30

    • 15; 30

    Correct Answer
    A. 30; 60
    Explanation
    IV 5HT-3 antagonists should be given 30 minutes prior to chemotherapy, while PO (oral) 5HT-3 antagonists should be given 60 minutes prior to chemotherapy.

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  • 19. 

    To avoid QT prolongation, the dose of ondansetron should not exceed ____mg/dose.

    • 32

    • 16

    • 12

    • 48

    Correct Answer
    A. 32
    Explanation
    To avoid QT prolongation, the dose of ondansetron should not exceed 32 mg/dose. QT prolongation is a condition where the heart takes longer than usual to recharge between beats, which can lead to abnormal heart rhythms. Ondansetron is a medication commonly used to prevent nausea and vomiting. However, it has been associated with QT prolongation at higher doses. Therefore, to minimize the risk of this side effect, the recommended maximum dose of ondansetron is 32 mg per dose.

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  • 20. 

    Dexamethasone is FDA approved for the prevention of CINV (Chemotherapy Induced Nausea and Vomiting).

    • True

    • False

    Correct Answer
    A. False
    Explanation
    It is used for this purpose but it is not FDA approved for this purpose.

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  • 21. 

    Dexamethasone works synergistically with ___________ and __________ to increase effectiveness by 20-30%

    • Metoclopramide

    • 5-HT3 antagonists

    • Olanzapine

    • Lorazepam

    Correct Answer(s)
    A. Metoclopramide
    A. 5-HT3 antagonists
    Explanation
    Dexamethasone works synergistically with Metoclopramide and 5-HT3 antagonists to increase effectiveness by 20-30%. This means that when Dexamethasone is combined with these medications, their overall effectiveness is enhanced and they work better together than if used individually. The combination of Dexamethasone with Metoclopramide and 5-HT3 antagonists leads to a greater therapeutic effect, potentially improving patient outcomes.

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  • 22. 

    Dexamethasone is used in acute and delayed N/V.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Dexamethasone is a corticosteroid medication that is commonly used to treat inflammation and suppress the immune system. It has been found to be effective in reducing nausea and vomiting (N/V) in both acute and delayed cases. This is especially useful in patients undergoing chemotherapy or radiation therapy, as these treatments often cause severe nausea and vomiting. Therefore, the statement that dexamethasone is used in acute and delayed N/V is true.

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  • 23. 

    Dexamethasone can cause transient perineal, vaginal, and renal burning so it should be at a slow rate for IV administration.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Dexamethasone, a medication commonly used to reduce inflammation, can cause temporary burning sensations in the perineal area, vagina, and kidneys when administered intravenously. To minimize discomfort, it is recommended to administer the medication at a slow rate. Therefore, the statement "Dexamethasone can cause transient perineal, vaginal, and renal burning so it should be at a slow rate for IV administration" is true.

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  • 24. 

    Dexamethasone does not have any major drug-drug interactions.

    • True

    • False

    Correct Answer
    A. False
    Explanation
    Dexamethasone interacts with Warfarin and the INR should be checked during concomitant use. Dexamethasone can increase the effects of warfarin sou counsel the patient to watch for dark stools.

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  • 25. 

    Which is the correct dosing and route for Fosaprepitant for CINV?

    • 150mg IV

    • 125mg PO

    • 150mg IV

    • 80mg PO

    Correct Answer
    A. 150mg IV
    Explanation
    The correct dosing and route for Fosaprepitant for CINV is 150mg IV. This means that Fosaprepitant should be administered intravenously at a dose of 150mg.

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  • 26. 

    Which is the correct dosing and route for Aprepitant? (Select all that apply)

    • 125mg PO

    • 80mg PO

    • 150mg IV

    • 40mg PO

    Correct Answer(s)
    A. 125mg PO
    A. 80mg PO
    A. 40mg PO
    Explanation
    40mg PO is for PONV and 125mg and 80mg are for CINV

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  • 27. 

    Neurokinin-1 Receptor Antagonists (NK1RA) are used in combination with ____________ and _____________ for prevention of acute and delayed N/V associated with highly and moderately emetogenic chemotherapy.

    • Steroids

    • 5HT-3

    • Olanzapine

    • Benzodiazepines

    • Promethazine

    Correct Answer(s)
    A. Steroids
    A. 5HT-3
    Explanation
    The three drugs should be taken 1 hour prior to chemo.

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  • 28. 

    Neurokinin-1 Receptor Antagonists (NK1RA) are only approved for CINV.

    • True

    • False

    Correct Answer
    A. False
    Explanation
    They are approved for CINV and PONV.

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  • 29. 

    What are some drug interactions for Aprepitant?

    • Oral contraceptives

    • Warfarin

    • 5-HT3 antagonists

    • Benzodiazepines

    • Corticosteroids

    Correct Answer(s)
    A. Oral contraceptives
    A. Warfarin
    A. Corticosteroids
    Explanation
    Reduces the effectiveness of oral contraceptives so patients need to use back up birth control for at least one month after using aprepitant or fosaprepitant. Aprepitant can increase the INR with Warfarin. The coritcosteroid DDI is why the dexamethasone dose needs to be decreased.

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  • 30. 

    What is the typical dose and route(s) for prochlorperazine for CINV?

    • 10mg IV/PO q6h scheduled or PRN

    • 12.5-25mg IV q4-6h schedule or PRN

    • 1-3mg IV/PO q2-4h PRN

    • 10-40mg IV/PO q6h

    Correct Answer
    A. 10mg IV/PO q6h scheduled or PRN
    Explanation
    The typical dose and route for prochlorperazine for CINV is 10mg IV/PO q6h scheduled or PRN. This means that the recommended dose is 10mg, which can be administered either intravenously or orally every 6 hours as scheduled or as needed. This dosage regimen allows for flexibility in the administration of the medication based on the patient's symptoms and response to treatment.

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  • 31. 

    What is the typical dose and route(s) for Promethazine for CINV?

    • 12.5-25mg IV/PO/IM/PR q4-6h schedule or PRN

    • 10mg IV/PO q6h scheduled or PRN

    • 1-3mg IV/PO q2-4h PRN

    • 10-40mg IV/PO q6h

    Correct Answer
    A. 12.5-25mg IV/PO/IM/PR q4-6h schedule or PRN
    Explanation
    The typical dose and route for Promethazine for CINV is 12.5-25mg, which can be administered intravenously, orally, intramuscularly, or rectally every 4-6 hours according to a schedule or as needed.

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  • 32. 

    Which drug has a black box warning for irreversible tardive dyskinesias.

    • Metoclopramide

    • Haloperidol

    • Promethazine

    • Prochlorperazine

    Correct Answer
    A. Metoclopramide
    Explanation
    Metoclopramide has a black box warning for irreversible tardive dyskinesias. Tardive dyskinesia is a movement disorder characterized by involuntary, repetitive movements of the face, tongue, and extremities. It is a potentially irreversible condition that can occur with the long-term use of certain medications, particularly antipsychotics and metoclopramide. The black box warning is the strongest warning issued by the FDA, indicating the serious and potentially life-threatening risk associated with the use of metoclopramide. Therefore, it is important for healthcare providers to carefully consider the risks and benefits before prescribing metoclopramide to patients.

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  • 33. 

    Which drug has a black box warning for QT prolongation

    • Droperidol

    • Promethazine

    • Prochlorperazine

    • Metoclopramide

    Correct Answer
    A. Droperidol
    Explanation
    Droperidol is the correct answer because it has a black box warning for QT prolongation. A black box warning is the strongest warning issued by the FDA, indicating that a drug carries a significant risk of serious or life-threatening side effects. QT prolongation is a condition that affects the heart's electrical activity and can lead to a potentially dangerous irregular heartbeat. Therefore, it is important to be cautious when prescribing or using droperidol due to this known risk.

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  • 34. 

    What is the drug of choice for anticipatory N/V?

    • Lorazepam

    • Olanzapine

    • Metoclopramide

    • Aprepitant

    Correct Answer
    A. Lorazepam
    Explanation
    Lorazepam is the drug of choice for anticipatory N/V because it is a benzodiazepine that acts as an anxiolytic and antiemetic. It helps to reduce anxiety and prevent nausea and vomiting that can occur before a chemotherapy session or surgery. By calming the patient's nerves, Lorazepam can effectively alleviate anticipatory N/V symptoms. Olanzapine, Metoclopramide, and Aprepitant may also be used to treat N/V, but Lorazepam is specifically recommended for anticipatory N/V.

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  • 35. 

    What is the appropriate dosing and route(s) for Lorazepam for CINV?

    • 1-2mg IV/PO/SL q4-6h PRN

    • 12.5-25mg IV/PO q4-6h PRN

    • 10-40mg IV/PO q4-6h scheduled or PRN

    • 1-2mg IV/IM q4-6h PRN

    Correct Answer
    A. 1-2mg IV/PO/SL q4-6h PRN
    Explanation
    Can also be take 1 dose prior to chemo

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  • 36. 

    Olanzapine works for N/V because it works on multiple dopaminergic, seratonergic, muscarinic, and histmainic receptors.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Olanzapine is a medication that works on multiple receptors in the brain, including dopaminergic, serotonergic, muscarinic, and histaminic receptors. These receptors play a role in regulating nausea and vomiting (N/V). By affecting these receptors, olanzapine can help alleviate N/V symptoms. Therefore, the statement that "Olanzapine works for N/V because it works on multiple dopaminergic, serotonergic, muscarinic, and histaminic receptors" is true.

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  • 37. 

    What is the dosing for Olanzapine for CINV?

    • 10mg PO daily x4d

    • 1-2mg PO daily x3d

    • 10-20mg PO daily x4d

    • 20mg PO daily x4d

    Correct Answer
    A. 10mg PO daily x4d
    Explanation
    Used in combo with 5-HT3 and steroids for prevention of highly emetogenic chemotherapy.

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  • 38. 

    What drug/drug class can be used for breakthrough N/V? (select all that apply)

    • 5-HT3

    • NK1RA

    • Benzodiazepines

    • Dopamine Antagonists

    • Steroids

    • Dronabinol

    Correct Answer(s)
    A. Benzodiazepines
    A. Dopamine Antagonists
    A. Steroids
    A. Dronabinol
    Explanation
    Benzodiazepines, dopamine antagonists, steroids, and dronabinol can be used for breakthrough N/V. Benzodiazepines are central nervous system depressants that can help relieve anxiety and nausea. Dopamine antagonists, such as metoclopramide or prochlorperazine, block dopamine receptors and can reduce nausea and vomiting. Steroids, such as dexamethasone, have anti-inflammatory properties and can help reduce nausea and vomiting. Dronabinol is a synthetic form of THC, the active component of marijuana, and can help relieve nausea and vomiting.

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  • 39. 

    Which drugs can be used for delayed N/V?

    • Palonsetron

    • Ondansetron

    • Olanzapine

    • Lorazepam

    • Aprepitant

    • Dexamethasone

    Correct Answer(s)
    A. Palonsetron
    A. Olanzapine
    A. Aprepitant
    A. Dexamethasone
    Explanation
    Palonsetron, Olanzapine, Aprepitant, and Dexamethasone can be used for delayed N/V. These drugs are commonly prescribed to prevent and treat delayed nausea and vomiting, which can occur after chemotherapy or surgery. Palonsetron is a serotonin receptor antagonist that helps in reducing nausea and vomiting. Olanzapine, an antipsychotic medication, has antiemetic properties and is effective in managing delayed N/V. Aprepitant is a neurokinin-1 receptor antagonist that works by blocking the signals that trigger nausea and vomiting. Dexamethasone, a corticosteroid, helps in reducing inflammation and suppressing the immune system, thereby alleviating symptoms of delayed N/V.

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  • 40. 

    Which drugs CANNOT be used for acute N/V?

    • Lorazepam

    • Promethazine

    • Prochlorperazine

    • Dronoabinol

    • Dexamthasone

    • Olanzapine

    Correct Answer(s)
    A. Lorazepam
    A. Promethazine
    A. Prochlorperazine
    A. Dronoabinol
    Explanation
    Lorazepam, Promethazine, Prochlorperazine, and Dronabinol are all drugs that can be used for acute N/V. Lorazepam is a benzodiazepine that can help relieve nausea and vomiting by reducing anxiety. Promethazine and Prochlorperazine are both antiemetic medications that can help control nausea and vomiting. Dronabinol is a synthetic form of THC, the active component of marijuana, and is used to treat chemotherapy-induced nausea and vomiting. Therefore, the correct answer is Olanzapine, which is an antipsychotic medication and is not typically used for acute N/V.

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  • 41. 

    Not all patients should have PRN option for breakthrough N/V.

    • True

    • False

    Correct Answer
    A. False
    Explanation
    ALL patients should have a PRN option. If one fails, try another or add. Use IV or PR formulations for uncontrolled N/V.

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  • 42. 

    What should be used for a patient who has a multiple day regimen of chemo?

    • 5-HT3 antagnoist

    • NK1RA

    • Dopamine antagonist

    • Benzodiazepine

    Correct Answer
    A. 5-HT3 antagnoist
    Explanation
    Palonsetron does not need to be given daily due to long half life.

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  • 43. 

    What is the dose for Granisetron for PONV?

    • 0.5-1mg IV at end of surgery

    • 2mg IV at end of surgery

    • 0.5-1mg at induction

    • 2mg IV at induction

    Correct Answer
    A. 0.5-1mg IV at end of surgery
    Explanation
    Granisetron is a medication commonly used for the prevention and treatment of postoperative nausea and vomiting (PONV). The recommended dose of Granisetron for PONV is 0.5-1mg administered intravenously at the end of surgery. This dose helps to control nausea and vomiting that may occur after the surgical procedure. Administering the medication at the end of surgery allows for optimal effectiveness in preventing PONV.

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  • 44. 

    What is the dose of Dolasetron in PONV?

    • 12.5mg IV at end of surgery

    • 100mg IV at end of surgery

    • 125mg IV at end of surgery

    • 25mg IV at end of surgery

    Correct Answer
    A. 12.5mg IV at end of surgery
    Explanation
    Dolasetron is a medication used to prevent postoperative nausea and vomiting (PONV). The correct dose of Dolasetron in PONV is 12.5mg IV at the end of surgery. This dose is administered intravenously and is effective in reducing the incidence of PONV. Higher doses, such as 100mg or 125mg, are not necessary and may increase the risk of side effects. A lower dose of 25mg may not provide sufficient antiemetic effect. Therefore, the recommended dose is 12.5mg IV at the end of surgery.

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  • 45. 

    What is the dose of Ondansetron for PONV?

    • 4mg IV at end of surgery

    • 8-16mg IV at induction

    • 8-16mg IV at end of surgery

    • 4mg IV at induction

    Correct Answer
    A. 4mg IV at end of surgery
    Explanation
    The correct answer is 4mg IV at end of surgery. Ondansetron is commonly used to prevent postoperative nausea and vomiting (PONV). The recommended dose for PONV is 4mg administered intravenously at the end of surgery. This timing ensures that the medication is in the patient's system when they wake up, reducing the likelihood of experiencing nausea and vomiting as a result of anesthesia. Higher doses (8-16mg) may be used in certain cases, but the standard dose is 4mg.

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  • 46. 

    What is the dose of Palonosetron in PONV?

    • 0.075mg IV at induction

    • 0.075mg IV at end of surgery

    • 0.25mg IV at induction

    • 0.25mg IV at end of surgery

    Correct Answer
    A. 0.075mg IV at induction
    Explanation
    Palonosetron is a medication used to prevent post-operative nausea and vomiting (PONV). The correct dose of Palonosetron in PONV is 0.075mg IV at induction. This means that the medication should be administered intravenously at the beginning of the surgery. This dose is effective in preventing nausea and vomiting that may occur after the surgery. It is important to administer the correct dose at the right time to ensure its effectiveness in managing PONV.

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  • 47. 

    What is the dose of Dexamethasone in PONV?

    • 2.5-5mg IV at induction

    • 2.5-5mg IV at end of surgery

    • 12-20mg IV at induction

    • 12-20mg IV at end of surgery

    Correct Answer
    A. 2.5-5mg IV at induction
    Explanation
    Dexamethasone is a corticosteroid commonly used to prevent postoperative nausea and vomiting (PONV). The recommended dose of Dexamethasone in PONV is 2.5-5mg IV at induction. This means that the medication should be administered intravenously (IV) at the beginning of the surgery to help prevent nausea and vomiting from occurring during the postoperative period. The dose range of 2.5-5mg is considered effective in reducing the incidence of PONV.

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  • 48. 

    What is the dosing for Promethazine in PONV?

    • 12.5-25mg IV at the end of surgery

    • 12.5-25mg IV at induction

    • 5-10mg IV at end of surgery

    • 5-10mg IV at induction

    Correct Answer
    A. 12.5-25mg IV at the end of surgery
    Explanation
    Promethazine is a medication commonly used for the prevention and treatment of postoperative nausea and vomiting (PONV). The correct dosing for Promethazine in PONV is 12.5-25mg IV at the end of surgery. This means that the medication should be administered intravenously in a dosage range of 12.5 to 25 milligrams at the conclusion of the surgical procedure. This timing allows for the medication to take effect and help prevent or alleviate any nausea and vomiting that may occur after surgery.

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  • 49. 

    What is the dosing for Prochlorperazine in PONV?

    • 5-10mg IV at end of surgery

    • 5-10mg IV at induction

    • 2.5-5mg IV at induction

    • 2.5-5mg IV at end of surgery

    Correct Answer
    A. 5-10mg IV at end of surgery
    Explanation
    Prochlorperazine is a medication commonly used for the prevention and treatment of postoperative nausea and vomiting (PONV). The correct dosing for Prochlorperazine in PONV is 5-10mg intravenously (IV) at the end of surgery. This timing ensures that the medication is administered after the surgical procedure is completed, reducing the risk of PONV during the immediate postoperative period. The dose range of 5-10mg allows for individualized treatment based on the patient's needs and response to the medication. IV administration is preferred for faster onset of action and reliable absorption.

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Quiz Review Timeline (Updated): Mar 22, 2023 +

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  • Current Version
  • Mar 22, 2023
    Quiz Edited by
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  • May 01, 2017
    Quiz Created by
    Ashleynecole

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