NCLEX Pharmacology Quiz 24 Hormonal And Reproductive Drugs

1. Julia is a mother who is receiving oxytocin therapy. The nurse must continuously evaluate:

Membrane integrity

Uterine contractions

Cervical dilation

Cervical effacement

A client receiving oxytocin therapy requires continuous monitoring of maternal vital signs. fluid intake and output. electronic fetal monitoring. and uterine contractions.

Explanation

A client receiving oxytocin therapy requires continuous monitoring of maternal vital signs. fluid intake and output. electronic fetal monitoring. and uterine contractions.

2. Which of the following is a contraindication for use of oxytocin to induce labor?

Missed abortion

Placenta previa

Hyperbilirubinemia

Pregnancy past due date

Use of oxytocin is contraindicated in the presence of placenta previa. Labor induction in this condition could be fatal to the fetus. Placenta previa is an indication for cesarean section.

Explanation

Use of oxytocin is contraindicated in the presence of placenta previa. Labor induction in this condition could be fatal to the fetus. Placenta previa is an indication for cesarean section.

3. During labor induction with oxytocin. the nurse knows that relaxation of vascular smooth muscle can cause:

Hypertension. premature atrial contractions

Hyperglycemia. premature ventricular contractions

Hyperglycemia. hypertension

Hypotension and flushing

Relaxation of vascular smooth muscle will cause vasodilation leading to hypotension and flushing.

Explanation

Relaxation of vascular smooth muscle will cause vasodilation leading to hypotension and flushing.

4. Estrogen is given in the management of all of the following conditions except:

Dysfunctional uterine bleeding

Primary hypogonadism

Suppression of ovulation

Endometrial carcinoma

Estrogen is given in the management of dysfunctional uterine bleeding. primary hypogonadism. and suppression of ovulation. Choices A. B. and C are all indicators for estrogen treatment.

Explanation

Estrogen is given in the management of dysfunctional uterine bleeding. primary hypogonadism. and suppression of ovulation. Choices A. B. and C are all indicators for estrogen treatment.

5. A constant dose of estrogen with varying doses of progestin are found in:

Monophasic pills

Depo-Provera

Triphasic pills

Biphasic pills

Choice A is incorrect because monophasic pills have a constant dose of estrogen and progestin throughout the month. Choice B is incorrect because Depo-Provera is a progestin product only. Choice C is incorrect because triphasic pills may have variations in estrogen as well as progestin levels.

Explanation

Choice A is incorrect because monophasic pills have a constant dose of estrogen and progestin throughout the month. Choice B is incorrect because Depo-Provera is a progestin product only. Choice C is incorrect because triphasic pills may have variations in estrogen as well as progestin levels.

6. Androgens are medically indicated in the management of all of the following except:

Hirsutism

Hypogonadism

Metabolic stimulation in prepubertal boys

Body building

Androgens can be dangerous drugs and are medically indicated only in severe conditions. such as female hirsutism or male hypogonadism. and as metabolic stimulator.

Explanation

Androgens can be dangerous drugs and are medically indicated only in severe conditions. such as female hirsutism or male hypogonadism. and as metabolic stimulator.

7. Progestins have been known to cause which of the following:

Decrease HDL level

Increase aspartate transaminase

Increase HDL levels

Decrease aspartate transaminase

Progestins decrease HDL levels. which may predispose the client to increased cardiac risk.

Explanation

Progestins decrease HDL levels. which may predispose the client to increased cardiac risk.

8. A relative contraindication to therapy with androgens is:

Hepatic failure

Pregnancy

Prostate cancer

Hypogonadism

Hepatic failure is considered a relative contraindication because antiandrogens have been known to cause hepatic toxicity. Choice B is incorrect because pregnancy is considered an absolute contraindication. Prostate cancer is an indication for antiandrogen administration. Hypogonadism would not be considered a contraindication. but it most certainly is not an indication for therapy.

Explanation

Hepatic failure is considered a relative contraindication because antiandrogens have been known to cause hepatic toxicity. Choice B is incorrect because pregnancy is considered an absolute contraindication. Prostate cancer is an indication for antiandrogen administration. Hypogonadism would not be considered a contraindication. but it most certainly is not an indication for therapy.

9. Which drug is used to manage preterm labor by causing smooth muscle relaxation?

Oxytocin

Prostaglandin

Ritodrine

Estrogen

Ritodrine is used to arrest uterine contractions in preterm labor. Oxytocin is used to stimulate labor.

Explanation

Ritodrine is used to arrest uterine contractions in preterm labor. Oxytocin is used to stimulate labor.

10. Which of the following drugs poses the greatest threat to an insulin-dependent diabetic who is pregnant?

Ritodrine hydrochloride

Oxytocin

Prostaglandin

Ergotrate

The only drug that poses a threat to diabetics who are pregnant is ritodrine.

Explanation

The only drug that poses a threat to diabetics who are pregnant is ritodrine.