Mini-end Of Module 5
.
- 1.All of the following are not true aboute dabigatrane except:
- A.
It undergo cytoplasmic p450 metabolism
- B.
It is irriversible competitive inhibitor of thrombin
- C.
It require frequant laboratory monitoring of clotting parameter
- D.
It has few drug -food interaction
- E.
It isnot potent and has many drug -drug interaction
- 2.A 50 year old female had come to the hospital 6 monthes ago suffering from severe pain in his right side investigations showed that she has proteinurea and she had been diagnosed as chronic renal failure she undergo dialysis and now she suffer from decreased in heamatocrite value that indicate that she has a severe anemia .. so the drug of choice for treatment of this case is:
- A.
Metformine
- B.
Erythropoitein
- C.
Methotrexate
- D.
Cyanochobolamine oral tablet
- 3.All of the following are true about crenation except
- A.
RBCs lose thier content of water and shrinkage occure
- B.
It occure when RBCsbis present in hypotonic solution
- C.
Their surface is not uniform with spiny protrusions
- D.
This process called echinocytosis
- 4.All of the following are of the content of eosinophils except :
- A.
Mojor basic proteins
- B.
Peroxidase enzyme
- C.
Histamin granules
- D.
Lysosomal hydrolytic enzymes
- 5.-lymphocytosis occure in all of the following except
- A.
Lymphatic leukemia
- B.
Syphilis
- C.
Tuberculosis
- D.
Small box infection
- 6.According to the cortex of the thymic lobule which is false:
- A.
T-lymphocytes present with all thier sizes
- B.
Epithelial reticular cells are of the content
- C.
They donnot has reticular connective tissue
- D.
Contain mocrophages larger in number than that of the medulla
- E.
Non of them is false
- 7.All of the following are ag presenting cell excepet
- A.
Follicular dendritic cell of the stromal lymph nodes
- B.
Langerhans dendritic cell of the skin
- C.
Macrophages
- D.
Epithelial reticular cell of the thymus
- 8.Concerning the structure of the marginal zone of the spleen, the true statement is
- A.
Contain B,T lymphocytes
- B.
Contain macrophages
- C.
Contain APCs
- D.
Doesn't contain plasma cells
- 9.All of the following are true about daap inguinal lymph nodes except :
- A.
They are few in number
- B.
They lie deep to the upper part of fascia lata lateral to femoral vein
- C.
They drain popliteal lymph nodes
- D.
They drain external illiac lymph nodes
- 10.Lymphatic arround cephalic vein drain into
- A.
Apical lymph nodes
- B.
Brachial lymph nodes
- C.
Subscapular lymph node
- D.
Centeral lymph nodes
- 11.All of the following is false about spleen except :
- A.
It lies parallel to the right ribs nomber 9,10,11 with long axis parallel to 10th rib
- B.
Its lower border is sharp and notched
- C.
Renal impression is found above the hilum
- D.
Lienorenal ligament is from lower border of spleen to the anterior surface of the kidney
- 12.All of the following is true about erythropoitein hormone except
- A.
The stimulus causes its production is hypoxia
- B.
Most of it is secreted by the kidney
- C.
This hormone is mainly formed of glycoprotein
- D.
When level of o2 transported to the tissue raised above normal the rate of erythropoitein formation increasedÂ
- E.
Both c & d
- 13.A nuclear explosion occured , many people dead the most common cause for their death is
- A.
Aplastic anemia
- B.
Hypoplastic anemia
- C.
Heamolytic anemia
- D.
Blood loss anemia
- 14.Blood group O+ persons has the following AB
- A.
Anti- a
- B.
Anti-b
- C.
Anti-D
- D.
All excepet c
- E.
All of them
- 15.Clotting can be prevented in vitro in case of
- A.
Deionizing ca+2 by reacting with sodium oxalate
- B.
Precipetating ca+2 with a substrate such as sodium oxalate
- C.
Precipetating ca+2 by substrate such as sodium citrate
- D.
Non of them
- 16.The following can be only present as in vivo anticoagulant except
- A.
Heparin
- B.
LMWH
- C.
Warfarine
- D.
Non of them
- 17.Maturation factors is/are
- A.
Vit B12
- B.
Vitamin C
- C.
Folic acid
- D.
Copper
- E.
A,b are correct
- 18.Normocytic normochromic anemia is charctarized by all of the following except
- A.
Occur in acute loss of blood and acute heamolytic anemia
- B.
Decrease RBCs content
- C.
Decreased haemoglobin
- D.
Normal hematocrite
- 19.All of the following are true about protein c except :
- A.
Found in the liver
- B.
Inhibit activity of both V , Vlll
- C.
Thrombine- thrombomoduline inhibit protein c
- D.
This protein cannot act without its cofactor protein S
- 20.-all of the following are true about idiopathic thrombocytopenic purpura except
- A.
It is autoimmune disease
- B.
Person has tendency to bleedfrom small capillaries more than large one
- C.
This disease cannot be treated because it is an autoimmune disease
- D.
Skin of this person has many small purplish blotches
- 21.All of the following are correct about heamoglobin synthesis except
- A.
Synthesis of coporphyrinogen is in the cytosole
- B.
Protoprphyrinogen III formed in mitochondoria
- C.
Porphyrinogen is coulerless
- D.
Porphyrines contain 6 extra hydrogen atomes compaired to porphyrinogen
- 22.All of the following is considered true about alpha type of thalassaemias except
- A.
There is decrease or abscent B-chain of heamoglobin
- B.
It is a type of heridatery haemolytic disease
- C.
HbH disease is subtype of it
- D.
It occure due to mutation in regulatory gene
- 23.All are true about congenital methmoglobinemia except
- A.
It may be due to mutation in globin biosynthesis
- B.
It may be due to defficiecy of NADH CYT b5 reductase system
- C.
Treatment with reducing agent is effiecient in case of Met Hb Reductase defficiency
- D.
In case of Hb-M ..treatment with reducing agent is efficient
- 24.All of the following is true about immunoglobulin except:
- A.
It is composed of 2 light and 2 heavy chain
- B.
There are 5 types of heavy chains with high molecular weight
- C.
Each 2 heavy chains are linked by disulphide bond
- D.
Each immunoglobuline has 2 binding site which are different
- 25.What is correct about immunoglobulin E
- A.
Present on the surface of B lymphocytes
- B.
It is produced in 1ry immune response
- C.
When antigen bind to this immunoglobulin they cause vasoconstriction and urtecaria
- D.
IgE protect agaisnt parasidic infection
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