Alkem Diabetology (PLS Attempt Quiz Until You Score At Least 90%.)
.
- 1.The Inhibitory activity of Evogliptin was___fold more potent than that of Sitagliptin.
- A.
10 Fold
- B.
5 Fold
- C.
100 Fold
- D.
2 Fold
- 2.Percentage of Evogliptin excreted via urine____%&Through Hepatic route___%.
- A.
50 & 50
- B.
34 & 66
- C.
30 & 70
- D.
40 & 60
- 3.Half life of Evogliptin______HRS.
- A.
30-50 HRS
- B.
18-24 HRS
- C.
24 HRS
- D.
32-39 HRS
- 4.Evogliptin is hepatically metabolized and it is neutral to_______enzyme unlike Saxagliptin hence no drug-drug interaction.
- A.
CYP1A2
- B.
CYP3A4
- C.
CYP2C19
- D.
CYPA4
- 5.What is the IC50 values of Evogliptin Vs Sitagliptin ?
- A.
0.98 nm & 19 nm
- B.
0.98 nm & 16.9 nm
- C.
7.5 nm &19 nm
- D.
None of these
- 6.M.R.P. of Valera per Tablet ?
- A.
Rs. 23
- B.
Rs. 18.75
- C.
Rs. 19.75
- D.
Rs. 21.85
- 7.Which option is true among following?
- A.
Evogliptin selectively binds to S1,S2 & S2 extensive sub-units.
- B.
Evogliptin selectively binds to S1,S2 sub-units
- C.
Evogliptin selectively binds to S1,S2,S1' & S2' extensive sub-units.
- D.
Evogliptin selectively binds to S1,S2 & S' sub-units
- 8.Zilokem CT offers greater BP control vs Olme+HCTZ and the combination lasting for more than 1.3 years.
- A.
True
- B.
False
- 9.Advantage of SMART Technology
- A.
Maintain 24hrs concentration and reduces toxicity
- B.
Avoid high blood concentration and increased patient compliance
- C.
Both A & B
- D.
Only A
- 10.In overweight & obese T2DM with elevated PPG, this indication related which brand ?
- A.
Glucoryl MV 1/2 0.3
- B.
Glucoryl MV 1/2
- C.
Glucoryl M 1/2/3/4 Forte
- D.
None of these
- 11.Evogliptin selectively inhibits______enzyme.
- A.
DPP-4
- B.
DPP-8
- C.
DPP-9
- D.
DPP-8 & DPP-9
- 12.DPP Enzyme stands for
- A.
Di-hydro Peptidyl Peptidase
- B.
Di-Phenyl Peptidase
- C.
Di-Peptidepeptidase
- D.
Di-Peptidyl Peptidase
- 13.The latest gliptin Evogliptin and Alkem has in licensed this product from the South Korea company called as
- A.
Daewoo Pharma
- B.
Dong Koo
- C.
DONG-A ST
- D.
None of these
- 14.The selectivity of Evogliptin for DPP-4 enzyme is________
- A.
>3000
- B.
>8000
- C.
>6000
- D.
>10000
- 15.Valera effectively improved Glycemic control at 24 week and showed similar efficacy to Vildagliptin in 184 indian patients inadequately controlled by metformin.
- A.
True
- B.
False
- 16.Evogliptin has mild hypoglycemic events,which were lower than Sitagliptin___Vs___ in a 24 week study.
- A.
0.8% vs 2.5%
- B.
0.9% vs 2.8%
- C.
0.2% vs 2%
- D.
1% vs 2.6%
- 17.As per the ACC/AHA 2016 guideline in ACS Patients post stent implantation, dual platelet therapy should be given for at least 12 month.
- A.
True
- B.
False
- 18.Indication of Rosukem CV
- A.
In Dyslipidemia with ASCVD with risk of MI/Stroke/PAD
- B.
In Secondary Prevention
- C.
Both A & B
- D.
None of these
- 19.Indication of Glucoryl MP 1/2
- A.
In overweight & obese type 2 Diabetics.
- B.
In overweight & obese type 2 Diabetics with elevated FPG & PPG
- C.
In T2DM on dual therapy with uncontrolled FPG & HbA1c
- D.
In Obese Uncontrolled T2DM Patients
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