Medications are put in place to either ease a patient’s pain or to revert them to health. Being that you are a pharmacology student, the one thing that you should do is ensure you know which types of drugs to prescribe and when. Take up the quiz below and get to see how much you know about respiratory and gastrointestinal medication.
Aspirin
Acetaminophen
Ibuprophen
Naproxen
Aspirin
Acetaminophen
Nalbumetone (Relafin)
Ibuprofen
Inhibit COX-1
Inhibit COX-2
Do not inhibit COX-1 or COX-2
Both A and B
Binding to CCK2 (cholecystekinin2) receptors to activate protein kinases to secrete H+ ions
Causing vasodilation and increased release of HCL from the islet cells
Inhibiting platelet aggregation whereby decreasing competition for H+ binding sites
Binding with H+ ions to create viscous coating of epithelial lining of the stomach
1-2 days
1-2 weeks
5-7 days
6-8 weeks
Vasodilation
Platelet aggregation
Gastric cytoprotection
Pain sensitization
Reducing stress
Avoiding aggrevating foods
Quit smoking
A 4 oz glass of red wine 3x/week
Pancreatic cancer
CHF
Wilm's tumor
HTN
Increases gastrin production
Decreases blood flow
Decreases healing
Decreases HCO3 production
Weakly inhibits cylcooxygenase
Metabolized in the liver via glucoronidation
Analgesic, antipyretic and anit-inflammatory effects
Interacts with Coumadin
High albumin binding
May decrease effects of ACE inhibitors
Reversibly inhibits thromboxane
Absorption is decreased with higher pH's
Aspirin
Acetaminophen
Diphenhydramine (Benadryl)
Warfarin
Present in low amounts in kidney, platelets and GI tract
Involved in thromboxane synthesis
Induced by cytokines
Renal vasodialtion
Provide analgesia at 50% of the anti-inflammatory dose
Reversibly inhibit the COX system
Are typically only well absorbed in the duodenem
Are highly plasma-protein binding
Bropheneramine (Veltane)
Indomethacin (Indocin)
Naproxen
Fenamic acid
Dextromethorophan
Hydrocodone
Celecoxib (Celebrex)
Meloxicam (Mobic)
Pseudoephedrine
Oxymetazoline
Tetrahydrazoline
Desloratadine (Clarinex)
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