Parkinsonism: Symptoms and Diagnosis! Trivia Knowledge Quiz

2.

Concerning the drugs used in parkinsonism. which of the following statements is accurate?

Levodopa causes postural hypotension
Useful therapeutic effects of amantadine continue for several years
The primary therapeutic benefit of antimuscarinic drugs in parkinsonism is their ability to reliever bradykinesia
Dopamine receptor against should not be used in Parkinson's disease prior to a trial of levodopa

Correct Answer

A. Levodopa causes postural hypotension

Explanation

Levodopa causes postural hypotension. This means that when taking levodopa, a person may experience a drop in blood pressure upon standing up, leading to dizziness or fainting. This side effect is commonly seen in patients with Parkinson's disease who are treated with levodopa. It is important for healthcare providers to monitor blood pressure and adjust the dosage of levodopa accordingly to minimize the risk of postural hypotension.

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3.

A 51-year-old patient with parkinsonism is being maintained on levodopa-carbidopa with adjunctive use of low doses of Entacapone, but continues to have off-periods of akinesia. The most appropriate drug to rescue the patient is:

Apomorphine
Benztropine
Carbidopa
Selegiline

Correct Answer

A. Selegiline

Explanation

Selegiline is the most appropriate drug to rescue the patient because it is a selective monoamine oxidase B (MAO-B) inhibitor. MAO-B inhibitors increase the levels of dopamine in the brain by blocking the breakdown of dopamine, thereby enhancing the effects of levodopa-carbidopa therapy. This can help to alleviate off-periods of akinesia in patients with parkinsonism. Apomorphine is a dopamine agonist that can also be used to rescue patients experiencing off-periods, but it is typically used when MAO-B inhibitors are ineffective or not tolerated. Benztropine is an anticholinergic agent that can be used to manage tremors in parkinsonism, but it is not the most appropriate drug for rescuing off-periods. Carbidopa is already being used in combination with levodopa and is not indicated as a rescue medication.

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1

4.

Which of the following anti-Parkinson drugs may cause peripheral vasospasm?

Amantadine
Bromocriptine
Carbidopa
Entacapone

Correct Answer

A. Bromocriptine

Explanation

Bromocriptine is an anti-Parkinson drug that may cause peripheral vasospasm. Vasospasm is the narrowing of blood vessels, which can reduce blood flow to certain areas of the body. This side effect of bromocriptine can lead to symptoms such as cold hands and feet, numbness, and pain in the affected areas. It is important for patients taking bromocriptine to be aware of this potential side effect and to report any symptoms to their healthcare provider.

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5.

A patient with parkinsonism is being treated with levodopa. He suffers from irregular, involuntary muscle jerks that affect the proximal muscles of the limbs. Which of the following statements about these symptoms is accurate?

Co-administration of muscarinic blockers prevents the occurrence of dyskinesia during treatment with levodopa
Dyskinesia are less likely to occur if levodopa is administered with carbidopa
Other drugs that activate dopamine receptors can exacerbate dyskinesia in a patient taking levodopa
The symptoms are likely to be alleviated by continued treatment with levodopa

Correct Answer

A. Other drugs that activate dopamine receptors can exacerbate dyskinesia in a patient taking levodopa

Explanation

Other drugs that activate dopamine receptors can exacerbate dyskinesia in a patient taking levodopa. This means that if the patient is taking other medications that stimulate dopamine receptors, it can worsen the involuntary muscle jerks that the patient is experiencing. Therefore, caution should be taken when prescribing other drugs that activate dopamine receptors to patients being treated with levodopa for parkinsonism.

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Parkinsonism: Symptoms And Diagnosis! Trivia Knowledge Quiz

Peripheral adverse effects of levodopa, including nausea, hypotension, and cardiac arrhythmias, can be diminished by including which of the following drugs in the therapy?

Quiz Preview

Concerning the drugs used in parkinsonism. which of the following statements is accurate?

A 51-year-old patient with parkinsonism is being maintained on levodopa-carbidopa with adjunctive use of low doses of Entacapone, but continues to have off-periods of akinesia. The most appropriate drug to rescue the patient is:

Which of the following anti-Parkinson drugs may cause peripheral vasospasm?

A patient with parkinsonism is being treated with levodopa. He suffers from irregular, involuntary muscle jerks that affect the proximal muscles of the limbs. Which of the following statements about these symptoms is accurate?