Hematology Chapter 16 Feb 2011

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Hematology Chapter 16 Feb 2011 - Quiz

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Questions and Answers
  • 1. 
    One of the ways you can differ Acute Leukemia from Chronic Leukemia is Leukemic cells are typically _____ in Acute Leukemia.
    • A. 

      Immature

    • B. 

      Mature

  • 2. 
    This type of Leukemia either acute or chronic affects all age. Which one is it?
    • A. 

      Acute

    • B. 

      Chronic

  • 3. 
    Chronic Leukemia typically affects what kind of people?
    • A. 

      Adults

    • B. 

      Children

  • 4. 
    80% of Acute Myeloid Leukemia is in ________.
    • A. 

      Children

    • B. 

      Adults

  • 5. 
    ______ regulates cell proliferation and regulation
  • 6. 
    Which of these would you not typically see in the Peripheral blood of AML?
    • A. 

      Myeloblast

    • B. 

      Promyelocyte

    • C. 

      Lymphoblasts

  • 7. 
    This description is more associated with which type of Leukemia? Medium to large blasts, more cytoplasm than lymphoblasts, cytoplasmic granules and Auer Rods
    • A. 

      AML

    • B. 

      ALL

  • 8. 
    This description is more associated with which type of Leukemia? The cytochemistry is this, negative peroxidase and sudan black, positive TdT.
    • A. 

      AML

    • B. 

      ALL

  • 9. 
    This description is more associated with which type of Leukemia? The cytochemistry is this, positive peroxidase and sudan black, negative TdT
    • A. 

      AML

    • B. 

      ALL

  • 10. 
    This description is more associated with which type of Leukemia? Small  or medium blasts, scarce cytoplasm, no granules
    • A. 

      AML

    • B. 

      ALL

  • 11. 
    Peroxidase is present in the  primary granules of ___ cells.
  • 12. 
    Is peroxidase present in lymphocytes or their precursors?
    • A. 

      Yes

    • B. 

      No

  • 13. 
    Which is more of a specific stain for granulocyte differentiation?
    • A. 

      Sudan Black B

    • B. 

      Peroxidase

  • 14. 
    Positive staining relating to Myeloperoxidase shows what color granules?
    • A. 

      Orange-red

    • B. 

      Blue-black

    • C. 

      Yellow-brown

    • D. 

      Purple-black

  • 15. 
    Peroxidase is present in the primary granules of the myeloid cells. Granules first appear in the early promyeloblast and persist through maturation
    • A. 

      True

    • B. 

      False

  • 16. 
    ____ is the most sensitive stain for granulocyte precursors, and is less specific than ____ in differentiating AML from ALL, but positively  seldom occurs in lymphoid cells.
    • A. 

      Sudan Black B, Myeloperoxidase

    • B. 

      Myeloperoxidase, Sudan Black B

  • 17. 
    Phospholipids occur in the _______ granules of  granulocytic cells.
    • A. 

      Primary

    • B. 

      Secondary

    • C. 

      Primary and secondary

    • D. 

      Tertiary

  • 18. 
    ____ is less specific than _______ in differentiating AML from ALL
    • A. 

      Sudan Black B, Myeloperoxidase

    • B. 

      Myeloperoxidase, Sudan Black B

  • 19. 
    Positive staining using Sudan Black B show what color cytoplasmic granules?
    • A. 

      Blue-Black

    • B. 

      Orange-Red

    • C. 

      Brown-Black

    • D. 

      Yellow-Brown

    • E. 

      Purple-Red

  • 20. 
    Chloroacetate esterase is negative for which of these?
    • A. 

      Eosinophils

    • B. 

      Neutrophils

    • C. 

      Mast cells

  • 21. 
    Chloroacetate esterase is negative for which of these?
    • A. 

      Basophils

    • B. 

      Neutrophils

    • C. 

      Monocytes

  • 22. 
    Chloroacetate esterase positive show what color  cytoplasmic granules?
    • A. 

      Blue-Black

    • B. 

      Bright Red

    • C. 

      Pale Yellow

    • D. 

      Brown-Black

  • 23. 
    Chloroacetate esterase most important use is in demonstrating myeloid differentiation in _____ -embedded tissue section.
  • 24. 
    Nonspecific esterase is primarily used to identify ________ cells.
  • 25. 
    Nonspecific esterase is negative in ______ cells.
    • A. 

      Monocytic

    • B. 

      Granulocytic

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