Gene Therapy MCQ Exam! Quiz

10 Questions | Total Attempts: 1797

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Genetics Quizzes & Trivia

Gene therapy refers to a technique in which a person's DNA is treated and examined to prevent genetic disease. The DNA is suitably chosen to correct the effects of a disease-causing mutation. This technique was developed in 1972. Take this quiz to test your knowledge and learn about the process and impact of gene therapy.


Questions and Answers
  • 1. 
    What Is Gene Therapy?
    • A. 

      Animals and Their Exact Clones in the world

    • B. 

      Treatments of Disorders and Diseases caused by inheritance

    • C. 

      Genetic Engineering

    • D. 

      Breeding of animals for an offspring

  • 2. 
    Who Invented Gene Therapy?
    • A. 

      William French Anderson

    • B. 

      Charles Darwin

    • C. 

      Gregor Mendel

    • D. 

      Michael Blaese

  • 3. 
    Is Gene Therapy an example of asexual or sexual reproduction and why?
    • A. 

      Sexual ; it needs a partner to happen

    • B. 

      Asexual ; it needs no partner to happen

    • C. 

      None of the above ; it has nothing to do with it

  • 4. 
    What is Gene Therapy said to have cured?
    • A. 

      Broken Limbs

    • B. 

      Aging in Humans & Animals

    • C. 

      Deadly Diseases

    • D. 

      None of the Above

  • 5. 
    Which gene is often inserted in an adenoviral vector to treat cancer by suicide gene therapy?
    • A. 

      HSV-TK

    • B. 

      IL-2

    • C. 

      GM-CSF

    • D. 

      VSV-G

  • 6. 
    Which deficiency was attempted to be treated in the first patient who died during a gene therapy experiment in 1999?
    • A. 

      Chronic Granulomatus Disorder

    • B. 

      Ornithine transcarbamylase

    • C. 

      Duchenne muscular dystrophy

    • D. 

      Adenosine deaminase deficiency

  • 7. 
    How are viruses referred to in which their envelope proteins have been replaced by other proteins, like VSV-G, to increase the tropism?
    • A. 

      Crippled viruses

    • B. 

      Replication deficient viruses

    • C. 

      Pseudotyped viruses

    • D. 

      Infectious viruses

  • 8. 
    A three-year-old boy was being treated for SCID using a modified retrovirus, but the boy developed a leukemia-like condition. What appeared to have caused this?
    • A. 

      The disorder is know to cause leukemia in most patients

    • B. 

      The retrovirus inserted near a proto-oncogene promoter

    • C. 

      The viral batch was contaminated with RCRs

    • D. 

      The retrovirus triggered the Human T-cell leukemia virus

  • 9. 
    What is in general, not a risk factor in gene therapy using adenoviruses?
    • A. 

      Insertional mutagenesis

    • B. 

      Overexpression leading to an immune reaction

    • C. 

      Generation of replication competent adenoviruses

    • D. 

      Toxicity due to the administered viral dose

  • 10. 
    What is not a product name for a replication-deficient adenoviral vector containing the p53 gene?
    • A. 

      Gendicine

    • B. 

      Advexin

    • C. 

      SCH58500

    • D. 

      Oncorine

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