Gene Therapy MCQ Exam! Quiz

10 Questions | By Asdfxdesi | Updated: Oct 17, 2022 | Attempts: 2881

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Gene therapy refers to a technique in which a person's DNA is treated and examined to prevent genetic disease. The DNA is suitably chosen to correct the effects of a disease-causing mutation. This technique was developed in 1972. Take this quiz to test your knowledge and learn about the process and impact of gene therapy.

Questions and Answers

1.

What Is Gene Therapy?
- A.
  
  Animals and Their Exact Clones in the world
- B.
  
  Treatments of Disorders and Diseases caused by inheritance
- C.
  
  Genetic Engineering
- D.
  
  Breeding of animals for an offspring
2.

Who Invented Gene Therapy?
- A.
  
  William French Anderson
- B.
  
  Charles Darwin
- C.
  
  Gregor Mendel
- D.
  
  Michael Blaese
3.

Is Gene Therapy an example of asexual or sexual reproduction and why?
- A.
  
  Sexual ; it needs a partner to happen
- B.
  
  Asexual ; it needs no partner to happen
- C.
  
  None of the above ; it has nothing to do with it
4.

What is Gene Therapy said to have cured?
- A.
  
  Broken Limbs
- B.
  
  Aging in Humans & Animals
- C.
  
  Deadly Diseases
- D.
  
  None of the Above
5.

Which gene is often inserted in an adenoviral vector to treat cancer by suicide gene therapy?
- A.
  
  HSV-TK
- B.
  
  IL-2
- C.
  
  GM-CSF
- D.
  
  VSV-G
6.

Which deficiency was attempted to be treated in the first patient who died during a gene therapy experiment in 1999?
- A.
  
  Chronic Granulomatus Disorder
- B.
  
  Ornithine transcarbamylase
- C.
  
  Duchenne muscular dystrophy
- D.
  
  Adenosine deaminase deficiency
7.

How are viruses referred to in which their envelope proteins have been replaced by other proteins, like VSV-G, to increase the tropism?
- A.
  
  Crippled viruses
- B.
  
  Replication deficient viruses
- C.
  
  Pseudotyped viruses
- D.
  
  Infectious viruses
8.

A three-year-old boy was being treated for SCID using a modified retrovirus, but the boy developed a leukemia-like condition. What appeared to have caused this?
- A.
  
  The disorder is know to cause leukemia in most patients
- B.
  
  The retrovirus inserted near a proto-oncogene promoter
- C.
  
  The viral batch was contaminated with RCRs
- D.
  
  The retrovirus triggered the Human T-cell leukemia virus
9.

What is in general, not a risk factor in gene therapy using adenoviruses?
- A.
  
  Insertional mutagenesis
- B.
  
  Overexpression leading to an immune reaction
- C.
  
  Generation of replication competent adenoviruses
- D.
  
  Toxicity due to the administered viral dose
10.

What is not a product name for a replication-deficient adenoviral vector containing the p53 gene?
- A.
  
  Gendicine
- B.
  
  Advexin
- C.
  
  SCH58500
- D.
  
  Oncorine