Substance Of Diuretics Quiz
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- 1.Which drug is the most commonly used loop diuretic
- A.
Furosemide
- B.
Torsemide
- C.
Bumetadine
- D.
Ethacrynic Acid
- 2.Which rug is potentially utilized by athletes to eliminate steroids from their body due the fact it is largely metabolized and fast acting?
- A.
Furosemide
- B.
Torsemide
- C.
Bumetadine
- D.
Erthracryic Acid
- E.
Urea
- F.
Mannitol
- 3.A 54 year old patient has a blood pressure of 185/110 and needs anti-hypertensive medication. The patient suffers from dermatitis and has a history of rashis following aminoglycoside treatment. Which of the following diuretics would be the best option for treating the high blood pressure?
- A.
Bumetadine
- B.
Furosemide
- C.
Torsemide
- D.
Ethracyric Acid
- 4.Which of the following would be most effective in preventing the hypokalemia caused by furosemide.
- A.
A drug that blocks Na+ channels in the collecting ducts
- B.
Increased aldosterone release
- C.
Increased vasopressin reslease
- D.
Administering flurosemide with metolazone
- 5.A 55 year old male with kidney stones has been placed on a diuretic. After af ew weeks he has a attack of gout. Which diuretic was he taking?
- A.
Flurosemide
- B.
Hydrocholorothiaizde
- C.
Spironolactone
- D.
Triameterne
- 6.Physiologically, which is the only area of the nephron where no salt reabsorption occurs
- A.
PCT
- B.
Thin Ascending Limb
- C.
Thick Ascending Limb
- D.
DCT
- E.
Collecting Duct
- 7.Concerning renal physiology, which area is the Na / K / 2Cl transporter found
- A.
PCT
- B.
Thin Descending Limb
- C.
Thick Ascending Limb
- D.
DCT
- E.
Collecting Ducts
- 8.Which drug would most likely to be used to treat a standard case of hypertension
- A.
Hydrochlorothiazide
- B.
Furosemdie
- C.
Torsemide
- D.
Bumetadine
- 9.A patient who has a poor kidney is also suffering from pulmonary edema. What drug do you give to treat them?
- A.
Furosemide
- B.
Torsemide
- C.
Hydrochlorothiazide
- D.
Metolazone
- 10.Which of the thiazides has the lowest oral bioavailability?
- A.
Hydrochlorothiazide
- B.
Chlorothiazide
- C.
Chlorthalidone
- D.
Metolazone
- E.
Indapmide
- 11.Why do thiazides have the strongest efect in releiving blood pressure?
- A.
Because of their secondary effect at the arterioles
- B.
Because of their effect on decreasing calcium
- C.
Because of the hypokalemia they sometimes induce
- D.
Because of hyperglycemia
- 12.The pharmacological actions of what class of drugs are classified ONLY by a increase in sodium loss and a increase in water loss?
- A.
Carbonic Anhydrase Inhibitors
- B.
Osmotic Diuretics
- C.
Loop Diuretics
- D.
Thiazide Diuretics
- E.
Na Channel Blockers
- F.
Aldosteron Antagonists
- 13.The parmacological actions of what class of drugs are classified ONLY by a decrease in sodium, decrease in cl, decrease in water, decrease in calcium, decrease in magnesium, and decrease in K reabsorption?
- A.
Osmotic Diuretics
- B.
Loop Diuretics
- C.
Carbonic Anhydrase inhibitors
- D.
K Spairing Diuretics
- 14.For the best diuretic efficacy, you would utilize a drug which targets which area of the nephron?
- A.
PCT
- B.
Thin Descending Limb
- C.
Thick Ascending Limb
- D.
DCT
- E.
Collecting Ducts
- 15.Aldosterone and ADH act at which area of the nephron?
- A.
PCT
- B.
Thin Descending Limb
- C.
Thick Ascending Limb
- D.
DCT
- E.
Collecting Ducts
- 16.Which of the following statements concering Na+ reabsorption is incorrect?
- A.
It can involve either active transport or passive diffusion mechanisms
- B.
Passive transport is mediated by the same transport mechanism body wide
- C.
Active transport is mediated by the Na / K transporter in the basolateral membrane
- D.
Salt tastes good on your sandwhich
- 17.Which fo the following statements concerning diuretics is false?
- A.
Aldosterone antagonists are synthetic steroids that can move from the blood to the lipid layer
- B.
All diuretics work by either actively or passivly flowing from the tubular lumen to their respective site of action
- C.
Loop diuretics have the highest efficacy in producing Na and water loss from the body
- D.
Furosemide is the most commonly used loop diuretic
- 18.A patient who is suffering from renal failure comes into your office complaining that he cannot pee. Which of the following drugs should you prescribe him for maximal immediate efficacy
- A.
Furosemide
- B.
Torsemide
- C.
Bumetadine
- D.
Hydrochlorothiazide
- E.
Chlorothiazide
- 19.Which of the following statements concering diuretics is TRUE?
- A.
Thiazide diuretics are the most effective class in lowering blood pressure
- B.
Co administration of thiazide diuretics and NSAIDs increase the overal efficacy of the drugs
- C.
Chlorothiazide has the highest oral bioavailability of the thiazides
- D.
Thiasides have a high efficacy and are very potent, they are thus indicated for short term treatment
- E.
Thiazides cause smooth muscle relaxation, vasoconrstiction, and increased peripheral resistance
- 20.A patient comes into your office who has had chronic trouble urinating. He also suffers from mild hypertension. Which treatment would be the best long term solution for his problem?
- A.
Indapamide
- B.
Furosemide
- C.
Torsemide
- D.
Bumetadine
- E.
Spironolactone
- 21.A Na / Ca exchanger is located on in what segment of the nephron on the apical side of the cell?
- A.
PCT
- B.
Thin Descending Limb
- C.
Thick Ascending Limb
- D.
DCT
- E.
Collecting Ducts
- 22.When administered, which drug would lead to a increase in plasma calcium levels?
- A.
Metolazone
- B.
Ethracryinc Acid
- C.
Bumetadine
- D.
Torsemide
- E.
Spironolactone
- 23.A common side effect of loop diuretics is hyponatremia. Which of the following compound would be given to best treat this?
- A.
Amiloride
- B.
Triametrene
- C.
Tolvapatan
- D.
Spironolactone
- E.
Canreone
- 24.Which of the following statements concerning diuretics is FALSE?
- A.
Canrenone is the active metabolite of spironolactone
- B.
Eplerenome has a strong anti-androgen effect
- C.
Potassium sparring drugs cause a decrease in Na channel expression, activity, and K channel expression
- D.
Potassiu sparring drugs cause a decrease in Na reabsorption, increase in K reabsorption, and a decrease in water reabsorption
- E.
Potassium sparring drugs are most commonly used in combination with a thiazide loop diuretic to prevent excess potassium loss
- 25.A patient walks into your office with a case of moderate hypertension. in order to most effectively treat him, what do you start him out on?
- A.
Hydrochlorothiazide
- B.
Hydrochlorothiazide + Eplerone
- C.
Furosemide
- D.
Furosemide + Spirolactone