COP 2015 Pharmaceutics Lecture from 08\/18\/2011 focuses on fundamental concepts of acid and base chemistry, including the strength of acidic and basic functional groups, and the characterization of amphiprotic molecules. This quiz assesses understanding of these chemical properties critical in pharmaceutical sciences.
Phenol, pKa 9-11
Sulfonic acid, pKa 0-1
Sulfonimide, pKa 5-6
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1.
2.
True
False
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True
False
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True
False
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PKa at which the amphiprotic molecule loses a proton, pKa1
PKa at which the amphiprotic molecule gains a proton, pKa2
PKw
Concentration
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5.7
8.3
-1.3
4.7
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Imine, pKa 3-4
Aromatic amine, pKa 5-6
Guanidine, pKa 10-11
Arylamine, pKa 4-5
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True
False
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Maleic acid
Chlorpheniramine
Chlorpheniramine maleate
Water
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Maleic acid
Chlorpheniramine
Chlorpheniramine maleate
Water
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A weak base
A weak acid
A strong base
A strong acid
Neutral
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A weak base
A weak acid
A strong base
A strong acid
Neutral
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The charged state
The uncharged state
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2.6
1.6
12.4
7
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