Cop 2015 Pharmaceutics Lecture 08/17/2011
15 Questions
| Total Attempts: 47
Questions and Answers
- 1.The cation K+, when added to a solution, increases the pH of that solution.
- A.
True
- B.
False
- 2.Strong bases, such as NaOH, produce strong conjugate acids.
- A.
True
- B.
False
- 3.Which of the following would decrease the pH of a solution?
- A.
Li+
- B.
Cl-
- C.
Fe3+
- D.
NO3-
- 4.
Which of the following is the correct Kb expression for the above reaction?- A.
A
- B.
B
- C.
C
- D.
D
- 5.When water is part of an acid/base reaction, H2O is always included in the Ka and Kb expressions as either a reactant or a product.
- A.
True
- B.
False
- 6.All transition metals, when added to solution, will cause the solution to:
- A.
Become more basic
- B.
Increase in pH
- C.
Both become more basic and decrease the pH
- D.
Become more acidic
- 7.
Fentanyl is used to induce anesthesia during hyperthermic treatment. During this treatment patients take longer to wake up because the Fentanyl is more active. Why is Fentanyl more active at higher temperatures? At 37C the pKa of Fentanyl is 8.22 At 42C the pKa of Fentanyl is 8.05
- A.
At the higher temperature, there is more charged Fentanyl. This allows it to be more reactive.
- B.
The higher temperature causes there to be more uncharged Fentanyl and therefore the Fentanyl is more hydrophillic
- C.
At the higher temperature, Fentanyl will be more uncharged than at lower temperatures, causing it to be absorbed easier and therfore more active
- 8.
Fentanyl is used to induce anesthesia during hyperthermic treatment. During this treatment patients take longer to wake up because the Fentanyl is more active. During this treatment, Fentanyl will exist mostly in: At 37C the pKa of Fentanyl is 8.22 At 42C the pKa of Fentanyl is 8.05
- A.
An acid state
- B.
An ionized state
- C.
An uncharged state
- 9.
Aspirin is an acidic drug that follows this basic equation: The pH of the ileum (the last portion of the small intestine) ranges from 7.0 - 8.0. Aspirin will be readily absorbed in the ileum.
- A.
True
- B.
False
- 10.For most drugs, the majority of absorption occurs in the duodenum.
- A.
True
- B.
False
- 11.
Aniline is shown in this figure. The pKa of Aniline is 4.6. Calculate the pH of a 0.03M Aniline solution.
- A.
8.54
- B.
9.2
- C.
7.0
- D.
3.5
- 12.Morphine is a basic drug. Morphine would exist mostly charged in the acidic stomach.
- A.
True
- B.
False
- 13.The cation NH4+, when added to a solution, increases the pH of that solution.
- A.
True
- B.
False
- 14.The anion Cl- is the conjugate base of a strong acid, when added to a solution, it does not change the pH of that solution.
- A.
True
- B.
False
- 15.If the pKa is less than the pKb, the solution will be acidic.
- A.
True
- B.
False
.png "Fentanyl is used to induce anesthesia during hyperthermic treatment. During this treatment patients take longer to wake up because the Fentanyl is more active. Why is Fentanyl more active at higher temperatures?
At 37C the pKa of Fentanyl is 8.22
At 42C the pKa of Fentanyl is 8.05")
.png "Aspirin is an acidic drug that follows this basic equation:
The pH of the ileum (the last portion of the small intestine) ranges from 7.0 - 8.0. Aspirin will be readily absorbed in the ileum.")
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