Pharmaceutics Quiz - Questions And Answers: Test Your Knowledge

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About This Quiz


Pharmaceutics, a captivating field, revolves around the study of medicines and their impact on the human body. Our Pharmaceutics Quiz Questions and Answers have been carefully crafted to provide both entertainment and education, challenging your comprehension of fundamental medicinal principles. This quiz serves as a valuable tool for examination preparation, encouraging you to test your grasp of pharmaceutical essential concepts. See more
Approach this quiz with care and concentration, as it can significantly aid in your academic pursuits. Understanding the intricacies of pharmaceutics is pivotal for healthcare professionals and researchers, ensuring the safe and effective application of medications.
So, immerse yourself in the quiz, confront your knowledge, and remain steadfast in your commitment to mastering this critical scientific domain. Best of luck on your journey of pharmaceutical exploration, and may your dedication to learning be as rewarding as it is enlightening! Keep up the diligent studying!

Pharmaceutics Quiz - Questions And Answers: Test Your Knowledge - Quiz

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  • 2. 

    Lanolin is

    • Hydrocarbon

    • An adsorption base

    • Water removable

    • None of these

    Correct Answer
    A. An adsorption base
    Explanation
    An ointment base refers to the vehicle or carrier substance in which the active ingredient of an ointment is dispersed. Lanolin is a commonly used ointment base that is derived from sheep's wool. It has excellent emollient properties and provides a protective barrier on the skin. The term "adsorption base" refers to an ointment base that has the ability to adsorb water or other substances onto its surface. Lanolin is known for its adsorptive properties, making it an appropriate choice for an adsorption base. Therefore, the correct answer is "Adsorption base."

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  • 3. 

    Given below are equipment used in the manufacture of following products P-T. Match them and find out correct answer 1. Zenasi (P) Tablet granules 2. Hepa filter (Q) Tablet coating 3. Chilsonator (R) Emulsion 4. Accela cota (S) Injectables   (T) Capsule

    • 1-p, 2-s, 3- p, 4-q

    • 1-P, 2-Q, 3-S, 4-R

    • (c) 1-T, 2-R, 3-Q, 4-P

    • 1-S, 2-R, 3-P, 4-Q

    Correct Answer
    A. 1-p, 2-s, 3- p, 4-q
    Explanation
    Zenasi could align with granulation (P).
    Hepa Filter ensures a sterile environment, necessary for Injectables (S).
    Chilsonator performs dry granulation, creating Tablet Granules (P).
    Accela Cota is designed for Tablet Coating (Q).

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  • 4. 

    Capping is prevented by using one of the following punches

    • Flat

    • Circular

    • Square

    • Rectangular

    Correct Answer
    A. Flat
    Explanation
    Capping, which refers to the formation of a raised area around the tablet edge, can be prevented by using a flat punch. This type of punch ensures that the compression force is evenly distributed across the tablet, resulting in a uniform and smooth surface. The flat punch helps to maintain the integrity of the tablet and prevents any excess material from being pushed to the edges, thus avoiding the occurrence of capping.

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  • 5. 

    Which of the following routes of administration is MOST likely to result in the first-pass effect?

    • Intravenous 

    • Sublingual 

    • Oral 

    • Transdermal

    Correct Answer
    A. Oral 
    Explanation
    The first-pass effect is a phenomenon where a drug's concentration is significantly reduced before it reaches systemic circulation. This is because the drug is metabolized by the liver after being absorbed from the gastrointestinal tract. Oral administration is the most common route to result in the first-pass effect.

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  • 6. 

    Calculate the amount of sodium chloride to make 1.5% solution of Pilocarpine hydrochloride isotonic with tear fluid. (Freezing point of 1% solution of Pilocarpine hydrochloride = -0.130C & freezing point of 1% sodium chloride solution = -0.5760C

    • 0.564w/v

    • 0.647 w/v

    • 0.430 w/v

    • 0.677 w/v

    Correct Answer
    A. 0.564w/v
  • 7. 

    Carr’s index is used to determine

    • Elasticity

    • Particle size

    • Sieve size

    • Flowability

    Correct Answer
    A. Flowability
    Explanation
    Carr's index is used to determine the flowability of a material. It is a measure of the compressibility and flow properties of a powder or granular material. A higher Carr's index indicates poor flowability, while a lower index suggests better flowability. By measuring the Carr's index, one can assess the ability of a material to flow freely and smoothly, which is important in various industries such as pharmaceuticals, food processing, and powder handling.

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  • 8. 

    Chewable tablet contains these base

    • Mannitol

    • Glucose

    • Lactose

    • None

    Correct Answer
    A. Mannitol
    Explanation
    The chewable tablet contains Mannitol as one of its base ingredients.

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  • 9. 

    Dose dumping is a problem in the formulation of

    • Compressed tab

    • Suppository

    • Soft gelatin capsules

    • Controlled release dug products

    Correct Answer
    A. Controlled release dug products
    Explanation
    Controlled release drug products are prone to dose dumping. Dose dumping refers to the rapid release of a large amount of drug from a formulation, which can lead to adverse effects or reduced therapeutic efficacy. This is particularly a concern with controlled release formulations because they are designed to release the drug gradually over a specific period of time. If dose dumping occurs, it can result in a sudden and potentially dangerous increase in drug concentration in the body. Therefore, it is important to carefully design and monitor controlled release drug products to prevent dose dumping.

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  • 10. 

    Which type of antioxidant work as reducing agent P) Ascorbic acid Q) Tocopherol R) Gallic acid S) Thiourea

    • P, S

    • P, R

    • R, S

    • Q, R

    Correct Answer
    A. P, S
    Explanation
    Ascorbic acid (P) and Thiourea (S) work as reducing agents. Ascorbic acid is a powerful antioxidant that can donate electrons to neutralize free radicals. Thiourea also has reducing properties and can act as an antioxidant by donating electrons to stabilize free radicals. Tocopherol (Q) and Gallic acid (R) are not mentioned as reducing agents in the given options.

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  • 11. 

    Base adsorption in capsules helps in determining

    • The flow property of capsule mixture

    • Amount of liquid absorbed by drug

    • Minimum capsule size

    • All of these

    Correct Answer
    A. Amount of liquid absorbed by drug
    Explanation
    Base adsorption in capsules refers to the process of the drug absorbing moisture from the surrounding environment. This is important because it can affect the stability and efficacy of the drug. The amount of liquid absorbed by the drug can impact its dissolution rate, bioavailability, and overall performance. Therefore, determining the amount of liquid absorbed by the drug is crucial in ensuring the effectiveness of the medication.

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  • 12. 

    Which of the following is not added in lozenges?

    • Sweetner

    • Binder

    • Disintegrant

    • All

    Correct Answer
    A. Disintegrant
    Explanation
    Disintegrants are substances that help the lozenges break down and dissolve in the mouth. They are added to promote the release of the active ingredients. Sweeteners, binders, and other excipients are commonly used in the formulation of lozenges to enhance taste, texture, and stability. Lozenges dissolve slowly. Therefore, disintegrants are not added in lozenges.

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  • 13. 

    Which of the following is NOT a factor influencing the dissolution rate of a solid drug in a liquid?

    • Viscosity of the liquid.

    • Temperature of the liquid.

    • Molecular weight of the drug.

    • Packaging material of the drug.

    Correct Answer
    A. Packaging material of the drug.
    Explanation
    The dissolution rate refers to how quickly a solid drug dissolves in a liquid to become a solution. Several factors influence this process:
    Particle size: Smaller particles dissolve faster due to increased surface area.
    Viscosity: Thicker liquids slow down the dissolution process.
    Temperature: Higher temperatures generally increase the dissolution rate.
    Molecular weight: This can influence the drug's solubility and, therefore, its dissolution rate.
    However, the packaging material does not directly affect the dissolution rate. While packaging is important for stability and storage, it doesn't alter the physical and chemical properties that govern dissolution.

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  • 14. 

    CAP dissolves at PH

    • Above 6

    • Below 6

    • 4

    • 2

    Correct Answer
    A. Above 6
    Explanation
    CAP (Cyclohexylamine) is a weak base and it dissolves in water to form its conjugate acid, which is cyclohexylammonium ion (C6H13NH3+). The solubility of a weak base increases with an increase in pH. When the pH is above 6, the concentration of hydroxide ions (OH-) in the solution is higher, which helps in the dissolution of the weak base. Therefore, CAP is more likely to dissolve at a pH above 6.

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  • 15. 

    In the tablet coating process, inadequate spreading of coating solution before drying causes

    • Orange peel effect

    • Sticking effect

    • Blistering effect

    • Picking effect

    Correct Answer
    A. Orange peel effect
    Explanation
    The inadequate spreading of the coating solution before drying in the tablet coating process can lead to the orange peel effect. This effect refers to the appearance of a rough, bumpy texture on the tablet surface, resembling the texture of an orange peel. It occurs when the coating solution does not spread evenly across the tablet surface, resulting in an uneven drying process. This can be caused by factors such as improper spray technique, high viscosity of the coating solution, or inadequate air flow in the coating equipment.

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  • 16. 

    Enteric coated tablet is disintegrated in

    • Stomach

    • Liver

    • Intestine

    • Mouth

    Correct Answer
    A. Intestine
    Explanation
    Enteric coated tablets are specifically designed to resist disintegration in the stomach and instead dissolve in the intestine. This is because certain medications can be irritating to the stomach lining or may be destroyed by stomach acid. The enteric coating allows the tablet to pass through the stomach without disintegrating, and only starts to dissolve once it reaches the more neutral pH environment of the intestine. This ensures that the medication is released in the appropriate location for absorption into the bloodstream.

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  • 17. 

    Which of the following one is used as opacifier

    • TiO2

    • MgO

    • Silites

    • All of the above

    Correct Answer
    A. TiO2
    Explanation
    TiO2 is used as an opacifier. Opacifiers are substances that are added to materials such as paints, ceramics, and plastics to make them opaque or less transparent. TiO2, also known as titanium dioxide, is a white pigment that is commonly used as an opacifier in various industries. It has excellent light-scattering properties, which allows it to effectively block or scatter light, resulting in opacity. This makes TiO2 a popular choice for achieving the desired opacity in a wide range of applications.

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  • 18. 

    Which drug is formulated as first pharmaceutical aerosol?

    • Epinehrine

    • Codeine

    • Chloropromazine

    • Probenecid

    Correct Answer
    A. Epinehrine
    Explanation
    Epinehrine is formulated as the first pharmaceutical aerosol because it was the first drug to be successfully aerosolized and delivered through inhalation. Aerosolization allows the drug to be converted into a fine mist or spray, which can then be inhaled into the lungs for rapid absorption and action. This method of delivery is particularly effective for drugs that need to act directly on the respiratory system, such as bronchodilators for asthma. Epinephrine, also known as adrenaline, is commonly used in aerosolized form to treat severe allergic reactions and asthma attacks.

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  • 19. 

    To dispense inhalation aerosols, which containers are used?

    • Stain less steel Containers

    • Tin plate

    • Glass

    • Al Containers

    Correct Answer
    A. Stain less steel Containers
    Explanation
    Stainless steel containers are used to dispense inhalation aerosols because they are durable, resistant to corrosion, and can withstand high pressure. They are also non-reactive, which ensures that the aerosol inside remains unaffected and does not interact with the container material. Additionally, stainless steel containers are easy to clean and maintain, making them suitable for storing and dispensing pharmaceutical products like inhalation aerosols.

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  • 20. 

    Green bone is a source of

    • Type A gelatin

    • Type B gelatin

    • Both 

    • None

    Correct Answer
    A. Type B gelatin
    Explanation
    Green bone is a source of Type B gelatin.

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  • 21. 

    Select the equation that gives the rate of drug dissolution from a tablet

    • Fick’s law

    • Henderson-Hasselbatch equation

    • Noyes-Whitney equation

    • Michelis Menton equation

    Correct Answer
    A. Noyes-Whitney equation
    Explanation
    The Noyes-Whitney equation is used to calculate the rate of drug dissolution from a tablet. It states that the rate of dissolution is directly proportional to the surface area of the tablet and the concentration difference between the drug in the tablet and its surrounding medium, and inversely proportional to the thickness of the diffusion layer. This equation is commonly used in pharmaceutical sciences to understand and predict the release of drugs from solid dosage forms.

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  • 22. 

    Propellant used in aerosol which may be vary from

    • 5-95%

    • 10-90%

    • 15-85%

    • 20-80%

    Correct Answer
    A. 5-95%
    Explanation
    The propellant used in aerosols can vary from 5% to 95%. This means that the concentration of propellant in an aerosol can range from as low as 5% to as high as 95%. The specific concentration depends on the formulation and purpose of the aerosol product. The propellant is responsible for expelling the product from the container, and different concentrations may be used to achieve the desired spray characteristics and performance.

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  • 23. 

    Colloidal silica (AEROSIL®) is used as

    • Diluent

    • Glidant

    • Disifectant

    • Lubricant

    Correct Answer
    A. Glidant
    Explanation
    Colloidal silica (AEROSIL®) is used as a glidant. A glidant is a material that is added to powders to improve their flowability and reduce the friction between particles. It helps to prevent the powder from clumping or sticking together, allowing for easier and more uniform filling of capsules or tablets. Colloidal silica has excellent gliding properties and is commonly used in pharmaceutical and cosmetic industries to enhance the flow characteristics of powders.

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  • 24. 

    Empty capsule has moisture content in the range of

    • 60%

    • 13%-16%

    • 50%- 70%

    • 30%

    Correct Answer
    A. 13%-16%
    Explanation
    Empty capsules typically have a moisture content in the range of 13%-16%. This moisture content is important because it affects the stability and integrity of the capsule. If the moisture content is too high, the capsule may become soft and lose its shape, making it difficult to handle and fill with medication. On the other hand, if the moisture content is too low, the capsule may become brittle and prone to cracking. Therefore, maintaining a moisture content within the range of 13%-16% ensures that the empty capsule remains stable and suitable for use in the pharmaceutical industry.

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  • 25. 

    The valve body /housing in an aerosol bottle valve assembly, is made from one of the following

    • Nylon

    • Polypropylene

    • Polly ethylene

    • Stainless Steel

    Correct Answer
    A. Nylon
    Explanation
    The valve body/housing in an aerosol bottle valve assembly is made from nylon. Nylon is a commonly used material for valve bodies due to its excellent strength, durability, and chemical resistance. It is also lightweight, which makes it ideal for aerosol applications. Nylon can withstand the pressure and temperature variations associated with aerosol products, ensuring the valve assembly functions effectively and safely. Additionally, nylon is a cost-effective option compared to materials like stainless steel.

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  • 26. 

    Which of the following substance is used as mucoadhesive

    • Acacia

    • Sodium CMC

    • Burnt sugar

    • Saccharin

    Correct Answer
    A. Sodium CMC
    Explanation
    Sodium CMC (Sodium Carboxymethylcellulose) is used as a mucoadhesive substance. Mucoadhesive substances are those that can stick to the mucous membranes, such as those in the mouth or nasal cavity, for an extended period of time. Sodium CMC is commonly used in pharmaceutical and oral care products due to its ability to adhere to the mucous membranes, providing sustained release of medication or prolonged contact time for oral products. Acacia, burnt sugar, and saccharin do not possess mucoadhesive properties.

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  • 27. 

    The equipment listed P-T is used for the identification of properties of aerosol mentioned below. Match them. 1. Particle size determination 2. Identification of propellants 3. Stability of foam 4. Flash point (P) Pycnometer (Q) Rotaional viscometer (R) Tag open cap apparatus (S) IR spectroscopy (T) Cascade impaction

    • 1-P, 2-Q, 3-R, 4-S

    • 1-Q, 2-P, 3-S, 4-T

    • 1-T, 2-S, 3-Q, 4-R

    • 1-R, 2-S, 3-P, 4-Q

    Correct Answer
    A. 1-T, 2-S, 3-Q, 4-R
    Explanation
    The equipment listed P-T is used for the identification of properties of aerosol mentioned below. The cascade impaction (T) is used for particle size determination. IR spectroscopy (S) is used for the identification of propellants. The rotational viscometer (Q) is used for stability of foam. The tag open cap apparatus (R) is used for flash point determination.

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  • 28. 

    PH of human tear is

    • 7.2

    • 8

    • 7.6

    • 4.6

    Correct Answer
    A. 7.2
    Explanation
    The correct answer is 7.2 because the pH of human tears is typically around 7.2. Tears are slightly acidic, with a pH range of 6.5 to 7.6, and 7.2 falls within this range. The pH level of tears is important for maintaining the health and function of the eyes, as it helps to protect the eyes from infections and irritants.

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  • 29. 

    Myrj 52 is

    • Polyoxy ethylene mono oleate

    • Polyoxy ethylene monolaurate

    • Polyoxy ethylene monostearate

    • Polyoxy ethylene lauryl ether

    Correct Answer
    A. Polyoxy ethylene monostearate
    Explanation
    Polyoxy ethylene monostearate is the correct answer because it is a type of surfactant that is commonly used in various industries such as cosmetics, pharmaceuticals, and food. It is derived from polyethylene glycol and stearic acid, and it acts as an emulsifier and stabilizer in products. It helps to improve the texture, stability, and shelf life of formulations by reducing surface tension and allowing better dispersion of ingredients.

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  • 30. 

    Cab-O-sil used as

    • Lubricant

    • Antiadhrent

    • Glidant

    • Disintegrant

    Correct Answer
    A. Glidant
    Explanation
    Cab-O-sil is a brand name for fumed silica, which is commonly used as a glidant in pharmaceutical formulations. A glidant is a substance that improves the flow properties of powders, making them easier to handle and process. It helps to reduce friction between particles, allowing them to move more freely and preventing clumping or sticking. Therefore, Cab-O-sil is used as a glidant to enhance the flowability of powders in pharmaceutical manufacturing processes.

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  • 31. 

    Match the coatings given below with their corresponding techniques listed P-T 1. Compression coating 2. Dip coating 3. Electrostatic coating 4. Vacuum film coating (P) Air in the coating pan is replaced with Nitrogen (Q) Application of coating to conductive substrates (R) Acid insoluble coating (S) A tablet within a tablet (T) Replaced coating & drying

    • 1-S, 2-R, 3-Q, 4-P

    • 1-Q, 2-R, 3-S, 4-T

    • 1-P, 2-R, 3-T, 4-S

    • 1-R, 2-T, 3-P, 4-Q

    Correct Answer
    A. 1-S, 2-R, 3-Q, 4-P
  • 32. 

    What is the use of methyl cellulose in ophthalmic solutions?

    • To protect eye

    • To increase ocular contact time

    • To decrease ocular contact time

    • As preservative

    Correct Answer
    A. To increase ocular contact time
    Explanation
    Methyl cellulose is used in ophthalmic solutions to increase ocular contact time. This means that it helps the solution to stay on the surface of the eye for a longer period of time, allowing for better absorption and effectiveness of the medication. By increasing the contact time, methyl cellulose ensures that the solution remains in contact with the eye for a sufficient duration, improving its therapeutic benefits.

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  • 33. 

    Among the propellants used in aerosols, one of the following is used for topical pharmaceutical aerosols

    • Tri chloro monofluoro methane

    • Di chloro difluoro methane

    • Di chloro tetrafluoro ethane

    • Propane

    Correct Answer
    A. Propane
    Explanation
    Propane is used as a propellant in topical pharmaceutical aerosols. Propane is a colorless and odorless gas that is easily liquefied, making it suitable for use in aerosol products. It has a low boiling point, which allows it to quickly vaporize and propel the active ingredients in the aerosol. Propane is also non-toxic and non-reactive, making it safe to use in pharmaceutical products.

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  • 34. 

    Which of the following dosage forms is generally considered to have the FASTEST onset of action?

    • Extended-release tablets 

    • Topical creams 

    • Intramuscular injections 

    • Oral capsules 

    • Sublingual tablets

    Correct Answer
    A. Sublingual tablets
    Explanation
    The onset of action refers to how quickly a drug starts producing its therapeutic effect. Sublingual tablets, which are placed under the tongue, are designed to dissolve rapidly and be absorbed directly into the bloodstream through the mucous membranes in the mouth. This bypasses the first-pass metabolism in the liver, resulting in a faster onset of action compared to other routes like oral administration.

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  • 35. 

    Which treatment is used for solubility of gelatin?

    • Heat

    • Formalin

    • Water

    • Alcohol

    Correct Answer
    A. Formalin
    Explanation
    Formalin is used for the solubility of gelatin. Formalin is a solution of formaldehyde gas in water, and it is commonly used as a fixative in histology to preserve tissues. When gelatin is treated with formalin, the formaldehyde molecules react with the gelatin proteins, causing them to cross-link and form a stable network. This process increases the solubility of gelatin and allows it to be used in various applications such as food, pharmaceuticals, and photography.

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  • 36. 

    Which one of these is tablet granulator?

    • Accella cota

    • Zanasi

    • Chilsonator

    • None of these

    Correct Answer
    A. Chilsonator
    Explanation
    The Chilsonator is a tablet granulator.

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  • 37. 

    Which one of the following propellant is used in the aerosol for oral use?

    • Propane

    • Oxygen

    • Methane

    • Tri chloro Monofluoro methane

    Correct Answer
    A. Tri chloro Monofluoro methane
    Explanation
    Tri chloro Monofluoro methane, also known as chlorofluorocarbon (CFC-11), is commonly used as a propellant in aerosols for oral use. It is a colorless gas that is non-toxic and non-flammable, making it suitable for use in medical and pharmaceutical products. CFC-11 has good solubility in liquids and provides a consistent and controlled release of the medication from the aerosol container. It is often used in inhalers, throat sprays, and other oral aerosol medications.

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  • 38. 

    Match the ingredients according to their purpose in the formulation. 1. Film coating 2. Syrups 3. Emulsification 4. Enteric coating (P) Sodium benzoate (Q) Ethyl cellulose (R) Eudragit (S) Sucrose (T) Sodium oleate

    • 1-P, 2-Q, 3-R, 4-S

    • 1-R, 2-S, 3-T, 4-Q

    • 1-T, 2-P, 3-S, 4-Q

    • 1-R, 2-S, 3-Q, 4-T

    Correct Answer
    A. 1-R, 2-S, 3-T, 4-Q
    Explanation
    1. Film coating is the purpose of Eudragit (R). 2. Syrups are made with Sucrose (S). 3. Emulsification is achieved with Sodium oleate (T). 4. Enteric coating is the purpose of Ethyl cellulose (Q).

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  • 39. 

    Polyvinyl acetate phthalate is used for

    • Sugar coating

    • Film coating

    • Enteric coating

    • None of these

    Correct Answer
    A. Enteric coating
    Explanation
    Polyvinyl acetate phthalate is used for enteric coating. Enteric coating is a process in which a protective layer is applied to a tablet or capsule to prevent it from dissolving in the stomach. This coating allows the medication to pass through the stomach intact and release in the intestines, where it is absorbed. Polyvinyl acetate phthalate is commonly used in enteric coating because it provides a barrier that is resistant to the acidic environment of the stomach.

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  • 40. 

    Match the following regions in GIT with the pH levels indicated from P-T and find out correct answer 1. Mouth 2. Stomach 3. Deodenum 4. Large intestine (P) 5-6 (Q) 6.8-7.5 (R) 6.8-7 (S) 3-5 (T) 1.5-3

    • 1-Q, 2-T, 3-S, 4-R

    • 1-P, 2-R, 3-S, 4-T

    • 1-S, 2-T, 3-Q, 4-R

    • 1-R, 2-S, 3-T, 4-P

    Correct Answer
    A. 1-Q, 2-T, 3-S, 4-R
    Explanation
    The correct answer is 1-Q, 2-T, 3-S, 4-R. The pH level in the mouth is slightly acidic, ranging from 6.8 to 7.5. The stomach has a highly acidic environment, with a pH level between 1.5 and 3. The small intestine, specifically the duodenum, has a slightly acidic to neutral pH level of 6.8 to 7. Lastly, the large intestine has a slightly acidic pH level of 5 to 6. Therefore, the given answer matches the correct pH levels for each region in the GIT.

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  • 41. 

    The plasticizers used  in  making soft gelatin capsules are

    • 10 to 17 % of wet gel base

    • 20 to 30 % of wet gel formulation

    • 5% of gelatin

    • 50 % of gelatin

    Correct Answer
    A. 20 to 30 % of wet gel formulation
    Explanation
    The plasticizers in making soft gelatin capsules are used in the preparation is 20 to 30% of wet gel formulation. Plasticizers are added to the gelatin to increase its flexibility and prevent it from becoming brittle. They help in improving the capsule's elasticity and durability, making it easier to swallow and preventing it from cracking or breaking easily. Adding plasticizers in the range of 20 to 30% ensures that the gelatin capsules have the desired softness and flexibility while maintaining their structural integrity.

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  • 42. 

    In the preparation of multi-layer tablets, one of the following is used for hydrophilic matrix coating.

    • Shellac

    • CMC

    • Stearyl alcohol

    • Bees Wax

    Correct Answer
    A. Shellac
    Explanation
    Shellac is used for hydrophilic matrix coating in the preparation of multi-layer tablets. Shellac is a natural polymer derived from the lac beetle and is known for its excellent film-forming properties. It forms a hydrophilic matrix when applied as a coating on tablets, allowing for controlled release of the drug. Shellac also provides protection to the tablet from moisture and other environmental factors. Therefore, it is commonly used as a coating material in the pharmaceutical industry.

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  • 43. 

    Crown thickness of a tablet is measured by

    • Micrometer

    • Pychnometer

    • Hydrometer

    • All of the above

    Correct Answer
    A. Micrometer
    Explanation
    The crown thickness of a tablet is measured using a micrometer. A micrometer is a precise measuring instrument that is commonly used to measure small distances or thicknesses with high accuracy. It consists of a calibrated screw mechanism that allows for precise measurement by turning the screw until it comes into contact with the object being measured. Therefore, a micrometer is the appropriate tool for measuring the crown thickness of a tablet.

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  • 44. 

    The identification of propellants in pharmaceutical aerosols is carried out by (P) Gas chromatography (R) Pycnometer (Q) Tag open cup apparatus (S) IR spectrophotometer

    • P, Q

    • P, S 

    • Q, R

    • R, S

    Correct Answer
    A. P, S 
    Explanation
    Gas chromatography and IR spectrophotometer are commonly used techniques for the identification of propellants in pharmaceutical aerosols. Gas chromatography separates the components of a mixture based on their different volatilities, allowing for the identification and quantification of propellants. IR spectrophotometer, on the other hand, measures the absorption of infrared radiation by the propellants, providing information about their chemical structure and allowing for their identification. Therefore, the correct answer is P, S.

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  • 45. 

    Plating of punch faces are done by

    • Chromium

    • Zinc

    • Iron

    • All

    Correct Answer
    A. Chromium
    Explanation
    The correct answer is Chromium because plating of punch faces is commonly done using chromium. Chromium plating provides excellent corrosion resistance, hardness, and wear resistance to the punch faces, making them more durable and long-lasting. It also gives a smooth and attractive finish to the punches. Zinc and iron plating are not typically used for punch faces, and the option "All" is not accurate as not all metals are suitable for plating punch faces.

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  • 46. 

    Aerosol packaging container must resist pressure of

    • 500 psig

    • 140-180 psig

    • 40 psig

    • 20 psig

    Correct Answer
    A. 140-180 psig
    Explanation
    The correct answer is 140-180 psig because aerosol packaging containers need to be able to withstand a certain amount of pressure. The range of 140-180 psig is within the acceptable pressure range for these containers. This ensures that the container will not burst or leak when it is being used or stored.

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  • 47. 

    Sta-Rx-1500 contains…% of moisture

    • 15

    • 10

    • 18

    • 50

    Correct Answer
    A. 10
    Explanation
    Sta-Rx-1500 contains 10% of moisture.

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  • 48. 

    Gasket is made up of

    • Buna-N

    • Neoprene rubber

    • Both

    • All

    Correct Answer
    A. Both
    Explanation
    The correct answer is "Both" because a gasket can be made up of Buna-N or Neoprene rubber. Buna-N is a synthetic rubber that is resistant to oil, fuel, and other chemicals, making it suitable for gaskets in various industries. Neoprene rubber, on the other hand, is known for its excellent resistance to weather, ozone, and oil, making it a common choice for gaskets in outdoor applications. Therefore, gaskets can be made from either Buna-N or Neoprene rubber, hence the answer "Both".

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  • 49. 

    Manufacturing of aerosol involves

    • Gas filling

    • Pressure filling

    • Cold filling

    • All the above

    Correct Answer
    A. Gas filling
    Explanation
    The manufacturing of aerosol involves gas filling, which refers to the process of filling the aerosol can with gas. This gas is usually a propellant that helps in dispensing the product from the can. Gas filling is an essential step in the manufacturing process of aerosol products.

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Amanda Nwachukwu |Pharm(D) |
Clinical Pharmacist
Amanda Nwachukwu, holding a Doctorate in Pharmacy from Texas Tech University Health Sciences Center, adeptly simplifies complex medical concepts into accessible content. With clinical proficiency, she ensures optimal patient care, while her adept medical writing skills facilitate comprehension and accessibility of healthcare information.

Quiz Review Timeline (Updated): Nov 7, 2024 +

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  • Nov 07, 2024
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  • Nov 21, 2019
    Quiz Created by
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