Learn More About Pharmaceutics - Pharmaceutics Review Quiz

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| By J_hutzly
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J_hutzly
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  • 1/128 Questions

    Enteric polymers are insoluble in acid and dissolve at pH 5.5 and above release the contents of the coated pellet, tablet or capsule in the duodenum and the upper small intestine.

    • True
    • False
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About This Quiz

Pharmaceutics is the discipline of pharmacy that deals with the process of turning a new chemical entity or old drugs into a medication to be used safely and effectively by patients. It is also called the science of dosage form design.
Learn More About Pharmaceutics in this Pharmaceutics Review Quiz

Learn More About Pharmaceutics - Pharmaceutics Review Quiz - Quiz

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  • 2. 

    Acceptable properties of aqueous suspensions include the following: The suspension vehicle should be viscous enough so that the patient gets a uniform dose, but not so viscous to prevent pouring

    • True

    • False

    Correct Answer
    A. True
    Explanation
    The statement suggests that for aqueous suspensions, it is desirable for the suspension vehicle to have a certain level of viscosity. It should be viscous enough to ensure that the patient receives a uniform dose, but not so viscous that it becomes difficult to pour. This is important because a uniform dose ensures that the medication is evenly distributed, while being able to pour the suspension easily allows for convenient administration. Therefore, the statement is true.

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  • 3. 

    Fick's 1st law of diffusion describes the passive diffusion process for percutaneous absorption; in other words, it describes the relationship where flux of a diffusing drug is proportional to concentration gradient

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Fick's 1st law of diffusion states that the flux or rate of diffusion of a drug through a membrane is directly proportional to the concentration gradient across the membrane. In other words, as the concentration difference between the two sides of the membrane increases, the rate of diffusion also increases. Therefore, the statement that Fick's 1st law of diffusion describes the relationship where flux of a diffusing drug is proportional to concentration gradient is true.

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  • 4. 

    Drugs that are not stable in light are said to degrade by a photolytic degradation process.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Drugs that are not stable in light undergo a process called photolytic degradation, where they break down or degrade when exposed to light. This process can result in changes to the chemical composition and effectiveness of the drug. Therefore, the statement that drugs that are not stable in light degrade by a photolytic degradation process is true.

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  • 5. 

    Friability, tablet hardness and tablet weight uniformity are all physical properties of compressed tablets

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Friability, tablet hardness, and tablet weight uniformity are all physical properties that can be measured and evaluated for compressed tablets. Friability refers to the ability of a tablet to withstand mechanical stress and remain intact during handling and packaging. Tablet hardness measures the resistance of a tablet to breakage or crumbling under pressure. Tablet weight uniformity ensures that each tablet in a batch has the same weight, which is important for accurate dosing. Therefore, it is true that these properties are all physical characteristics of compressed tablets.

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  • 6. 

    Preformulation testing enables companies to develop robust formulations by determining the fundamental physical and chemical properties of the NCE prior to designing the formulation for that dosage form

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Preformulation testing is an essential step in the development of pharmaceutical formulations. It involves evaluating the physical and chemical properties of a new chemical entity (NCE) before designing the formulation for a specific dosage form. By conducting preformulation testing, companies can gather crucial information about the NCE's solubility, stability, compatibility, and other properties. This knowledge helps in designing robust formulations that are stable, effective, and safe for patients. Therefore, the statement that preformulation testing enables companies to develop robust formulations by determining the fundamental physical and chemical properties of the NCE prior to designing the formulation is true.

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  • 7. 

    Amphiphilic molecules used to stabilize pharmaceutical emulsions are not completely hydrophobic or hydrophilic

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Amphiphilic molecules used to stabilize pharmaceutical emulsions have both hydrophobic and hydrophilic properties. This means that they can interact with both water and oil components in the emulsion, helping to prevent separation and maintain stability. If these molecules were completely hydrophobic or hydrophilic, they would not be able to effectively stabilize the emulsion. Therefore, the statement that they are not completely hydrophobic or hydrophilic is true.

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  • 8. 

    Myocet is a liposomal drug delivery system containing doxorubicin citrate and is used to treat various types of cancer

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Myocet is indeed a liposomal drug delivery system that contains doxorubicin citrate. It is commonly used in the treatment of different types of cancer. Therefore, the statement is true.

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  • 9. 

    Prodrug is a term used to describe a compound that requires metabolic biotransformation after administration to produce the pharmacologically active compound

    • True

    • False

    Correct Answer
    A. True
    Explanation
    A prodrug is a compound that is administered in its inactive form and needs to undergo metabolic biotransformation in the body to become the active pharmacologically active compound. This process is necessary for the prodrug to exert its therapeutic effects. Therefore, the statement given in the question is true.

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  • 10. 

    The rate of settling of drug particles suspended in an aqueous vehicle is controlled by the radius of the drug particles, the viscosity of the dispersion medium and the difference between the density of the aqueous vehicle and the density of the drug substance

    • True

    • False

    Correct Answer
    A. True
    Explanation
    The rate at which drug particles suspended in an aqueous vehicle settle is influenced by several factors. The radius of the drug particles affects the settling rate, with larger particles settling more quickly. The viscosity of the dispersion medium also plays a role, as higher viscosity slows down settling. Additionally, the difference in density between the aqueous vehicle and the drug substance affects settling, with greater density differences leading to faster settling. Therefore, the statement that the rate of settling is controlled by these factors is true.

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  • 11. 

    The Turbuhaler is a dry powder inhaler that is a multi-dose reservoir device. Reservoir devices use metering mechanisms located inside the device, and this allows many doses to be packaged compactly but they require improved moisture protection and have more dosing variability

    • True

    • False

    Correct Answer
    A. True
    Explanation
    The explanation for the given correct answer is that the Turbuhaler is indeed a dry powder inhaler that is a multi-dose reservoir device. Reservoir devices have metering mechanisms inside them, which allow for compact packaging of multiple doses. However, these devices require better protection from moisture and may have more variability in dosing. Therefore, the statement is true.

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  • 12. 

    Gels are semi-solid colloidal systems in which the movement of the dispersion medium is restricted by an interlacing network of solvated particles

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Gels are indeed semi-solid colloidal systems where the dispersion medium's movement is limited by a network of solvated particles. This network forms a three-dimensional structure that traps the dispersion medium, giving gels their characteristic semi-solid consistency. Therefore, the statement is true.

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  • 13. 

    Nebulizer formulations typically contain a drug dissolved or suspended in a liquid carrier (e.g., purified water) containing an osmotic agent (e.g., sodium chloride) and a buffering agent (e.g., citrate buffer)

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Nebulizer formulations commonly consist of a medication dissolved or suspended in a liquid carrier. This liquid carrier often includes an osmotic agent like sodium chloride and a buffering agent such as citrate buffer. This statement is true as it accurately describes the typical composition of nebulizer formulations.

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  • 14. 

    The rate of dissolution of fentanyle in purified water at 37*C depends on its particle size and the degree of agitation being used to stir the system

    • True

    • False

    Correct Answer
    A. True
    Explanation
    The rate of dissolution of fentanyl in purified water at 37°C is influenced by two factors: particle size and agitation. Smaller particle sizes have a larger surface area, allowing for faster dissolution. Additionally, the degree of agitation affects the rate of dissolution as it helps in breaking down the particles and increasing the contact between the drug and the solvent. Therefore, both particle size and agitation play a role in determining the rate of dissolution of fentanyl in purified water at 37°C.

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  • 15. 

    Physico-chemical properties of a drug include the aqueous solubility, drug stability and its pKa

    • True

    • False

    Correct Answer
    A. True
    Explanation
    The statement is true because physico-chemical properties of a drug do include aqueous solubility, drug stability, and pKa. Aqueous solubility refers to the ability of a drug to dissolve in water, which is an important factor in its absorption and distribution in the body. Drug stability refers to the ability of a drug to maintain its chemical and physical properties over time, ensuring its efficacy and safety. pKa is a measure of the acidity or basicity of a drug, which affects its solubility and absorption. Therefore, all these properties are essential in understanding and predicting the behavior of a drug in the body.

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  • 16. 

    Film coating s have been used to mask the taste of drugs, to improve drug stability and also to control the release rate of the drug from pellets and tablets

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Film coatings are commonly used in the pharmaceutical industry for various purposes. They can be used to mask the unpleasant taste of drugs, making them more palatable for patients. Additionally, film coatings can improve the stability of drugs by protecting them from moisture, light, and other environmental factors that may degrade their effectiveness. Moreover, film coatings can control the release rate of the drug from pellets and tablets, allowing for a more controlled and sustained release of the medication in the body. Therefore, the statement that film coatings have been used for these purposes is true.

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  • 17. 

    The surface area of a powder increases when the particle size is decreased.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    When the particle size of a powder is decreased, the total surface area of the particles increases. This is because smaller particles have a larger surface area compared to larger particles of the same material. As the particle size decreases, the number of particles increases, resulting in more surface area available for interactions or reactions. Therefore, it is true that the surface area of a powder increases when the particle size is decreased.

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  • 18. 

    A thermolabile drug is one that is unstable to heat.  Lamination or capping of a tablet can results from poor bonding between granules in a tablet compact.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    The statement is true because a thermolabile drug is one that is unstable to heat. This means that when exposed to heat, the drug can degrade or become less effective. Lamination or capping of a tablet occurs when there is poor bonding between the granules in the tablet compact. This can happen due to various factors, including the use of a thermolabile drug that becomes unstable and causes the tablet to break apart. Therefore, the statement is true as it correctly states the relationship between thermolabile drugs and the occurrence of lamination or capping in tablets.

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  • 19. 

    When Cilostazol, a water-insoluble crystalline drug substance, was dosed in an aqueous suspension to beagle dogs, it was found that the 220 nm diamter particle size of Cilostazole had greate bioavailability than the 13 micron diameter particle size

    • True

    • False

    Correct Answer
    A. True
    Explanation
    The statement suggests that when Cilostazol is given to beagle dogs in an aqueous suspension, the smaller particle size of 220 nm diameter has greater bioavailability compared to the larger particle size of 13 micron diameter. This implies that the smaller particles are more easily absorbed and utilized by the dogs, leading to higher bioavailability. Therefore, the statement is true.

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  • 20. 

    Dehydrated Alcohol USP should be used to extemporaneously compound prescriptions when "essentially water free" alcohol is required

    • True

    • False

    Correct Answer
    A. True
    Explanation
    This statement is true because Dehydrated Alcohol USP is specifically designed to be "essentially water free." This means that it contains only a minimal amount of water, making it suitable for compounding prescriptions that require alcohol without any significant water content. Using Dehydrated Alcohol USP ensures that the desired level of alcohol concentration is achieved without any dilution from water, which may be necessary for certain medications or formulations.

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  • 21. 

    Allegra D is a bilayer tablet product whereas Effexor XR is an extended release capsule product containing coated pellets.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    The explanation for the given correct answer is that Allegra D is indeed a bilayer tablet product, meaning it is composed of two layers with different release profiles. On the other hand, Effexor XR is an extended release capsule product that contains coated pellets, which allows for a controlled and prolonged release of the medication. Therefore, the statement is true as it accurately describes the formulation of these two products.

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  • 22. 

    Drugs classified as BCS I are more soluble than drugs classified as BCS II or BCS IV

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Drugs classified as BCS I are more soluble than drugs classified as BCS II or BCS IV. This means that BCS I drugs have a higher ability to dissolve in a solvent, such as water, compared to BCS II or BCS IV drugs. Solubility is an important factor in drug absorption and bioavailability, as drugs need to dissolve in order to be absorbed into the bloodstream and exert their therapeutic effects. Therefore, this statement is true.

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  • 23. 

    When selecting a suspending agent to retard particle settling and promote dispersion stability, the suspending agent and the drug substance must be chemically compatible

    • True

    • False

    Correct Answer
    A. True
    Explanation
    The statement is true because when selecting a suspending agent, it is important to ensure that it is chemically compatible with the drug substance. If the suspending agent and the drug substance are not compatible, it can lead to chemical reactions or degradation of the drug substance, which can affect its efficacy and stability. Therefore, it is crucial to choose a suspending agent that is compatible with the drug substance to maintain its stability and prevent particle settling.

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  • 24. 

    The Zeta Potential is a measure of the magnitude of the repulsion or attraction between dispersed particles

    • True

    • False

    Correct Answer
    A. True
    Explanation
    The explanation for the given correct answer is that the Zeta Potential indeed measures the strength of the repulsive or attractive forces between particles that are dispersed in a liquid medium. It provides information about the stability and behavior of colloidal systems. A high magnitude of Zeta Potential indicates strong repulsion between particles, leading to better dispersion and stability of the system. Conversely, a low magnitude of Zeta Potential suggests weak repulsion or attraction, which can result in particle aggregation and instability. Therefore, the statement is true.

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  • 25. 

    Petrolatum and Yellow Ointment are examples of hydrocarbon ointment bases used in pharmaceutical compounding

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Petrolatum and Yellow Ointment are indeed examples of hydrocarbon ointment bases used in pharmaceutical compounding. These ointment bases are commonly used in the preparation of various topical medications. Petrolatum, also known as petroleum jelly, is a semisolid mixture derived from petroleum and is widely used as a moisturizer and protectant for the skin. Yellow Ointment, on the other hand, is a mixture of petrolatum and yellow wax, which provides a smooth and greasy texture to the ointment. Therefore, the statement is true.

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  • 26. 

    Carbopol polymers used to prepare an aqueous gel must be neutralized in order to achieve maximum viscosity; and an example of a water soluble neutralizing agent suitable for neutralizing Carbopol polymeres is trieathanolamine

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Carbopol polymers are commonly used to prepare aqueous gels, but they need to be neutralized to achieve their maximum viscosity. One example of a water-soluble neutralizing agent suitable for this purpose is triethanolamine. This means that the statement is true.

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  • 27. 

    Lupron contains leuprolide acetate and is used for the treatment of prostate cancer

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Lupron is a medication that contains leuprolide acetate, which is indeed used for the treatment of prostate cancer. Leuprolide acetate is a hormone therapy drug that works by reducing the production of testosterone in the body, which can help slow down the growth of prostate cancer cells. Therefore, the statement is true.

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  • 28. 

    An example of a viscosity enhancing suspending agent appropriate for orally administered aqueous suspensions is acacia

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Acacia is a commonly used viscosity enhancing suspending agent in orally administered aqueous suspensions. It helps to increase the thickness and stability of the suspension, allowing the drug particles to remain evenly dispersed throughout the liquid. This is important for ensuring uniform dosing and preventing settling of particles. Therefore, the statement that acacia is an appropriate viscosity enhancing suspending agent for orally administered aqueous suspensions is true.

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  • 29. 

    Epivir Oral Solution contains the co-solvent, propylene glycol, because the API, lamivudine, is only "sparingly soluble" in water at 25*C

    • True

    • False

    Correct Answer
    A. True
    Explanation
    The explanation for the given correct answer is that the co-solvent, propylene glycol, is added to the Epivir Oral Solution because the active pharmaceutical ingredient (API), lamivudine, is only "sparingly soluble" in water at 25°C. This means that without the addition of propylene glycol, the lamivudine would not dissolve properly in the solution and would not be effective. Therefore, the presence of propylene glycol as a co-solvent is necessary to enhance the solubility of lamivudine and ensure its efficacy in the oral solution.

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  • 30. 

    Ability Oral solution, whihc contains aripiprazole as the API is "practically insoluble" in water at 25*C, and its solubility is pH dependent

    • True

    • False

    Correct Answer
    A. True
    Explanation
    The given statement is true. It states that the Ability Oral solution, which contains aripiprazole as the active pharmaceutical ingredient (API), is "practically insoluble" in water at 25°C. This means that aripiprazole has very low solubility in water at this temperature. Additionally, the solubility of aripiprazole is pH dependent, indicating that it may dissolve better or worse in water depending on the pH level of the solution.

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  • 31. 

    Levaquin, a fluoroquinolone, is levofloxacin hemihydrate

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Levaquin is indeed a fluoroquinolone antibiotic, and its active ingredient is levofloxacin hemihydrate. Therefore, the statement "Levaquin, a fluoroquinolone, is levofloxacin hemihydrate" is true.

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  • 32. 

    For colloidal dispersions, flow is an important property. Glycerin and diluted Simple Syrup NF exhibit Newtonian flow, meaning the rate of shear is linearly related to shearing stress.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Colloidal dispersions are a type of mixture where small particles are dispersed in a medium. In this case, the medium is either glycerin or diluted Simple Syrup NF. Newtonian flow refers to the property where the rate of shear (deformation) is directly proportional to the shearing stress applied. This means that as more stress is applied, the flow rate increases linearly. The statement suggests that both glycerin and diluted Simple Syrup NF exhibit this type of flow behavior, making the answer true.

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  • 33. 

    Methylcellulose at a 2% concentration in purified water is neutrally charged, where as Alginic Acid at a 0.5% concentration is negatively charged in purified water.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    The explanation for the given correct answer is that the statement is stating a fact about the charges of Methylcellulose and Alginic Acid at specific concentrations in purified water. It states that Methylcellulose at a 2% concentration is neutrally charged, meaning it has no net positive or negative charge. On the other hand, Alginic Acid at a 0.5% concentration is negatively charged, indicating that it has an excess of negative charges. This information is provided as a true statement, indicating that the charges of these substances in purified water are as described.

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  • 34. 

    Examples of viscosity enhancing agents appropriate for topically applied aqueous suspensions include magnesium aluminum silicate (i.e. Veegum) and sodium carboxymethylcellulose

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Viscosity enhancing agents are substances that increase the thickness or stickiness of a liquid. In the context of topically applied aqueous suspensions, such as creams or gels, magnesium aluminum silicate (Veegum) and sodium carboxymethylcellulose are appropriate viscosity enhancing agents. These agents help to improve the consistency and stability of the suspension, allowing it to be easily applied and stay in place on the skin. Therefore, the statement is true.

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  • 35. 

    Cellulose derivatives, such as methylcellulose, are hydrophilic polymers used in both internally administered and externally applied suspensions

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Cellulose derivatives, such as methylcellulose, are indeed hydrophilic polymers that can be used in both internally administered and externally applied suspensions. These derivatives have the ability to absorb water and form a gel-like substance, making them suitable for various pharmaceutical and cosmetic applications.

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  • 36. 

    According to the descriptive terms of solubility used by the USP, if Cisapride is practically insoluble in water, then more than 10,000mL of water is requied to dissolve 1g of Cisapride

    • True

    • False

    Correct Answer
    A. True
    Explanation
    According to the descriptive terms of solubility used by the USP, if a substance is practically insoluble in water, it means that a large amount of water is required to dissolve a small amount of the substance. In this case, it is stated that more than 10,000mL of water is required to dissolve 1g of Cisapride, which indicates that Cisapride is indeed practically insoluble in water. Therefore, the answer is true.

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  • 37. 

    A major impediment to pulmonary aerosol delivery is the pharyngeal barrier; and advising the patient to slowly inhale from a spacer device used with a pMDI can partially eliminate the pharyngeal barrier

    • True

    • False

    Correct Answer
    A. True
    Explanation
    The explanation for the given correct answer is that the pharyngeal barrier is a major obstacle to delivering aerosol medication to the lungs. By using a spacer device with a pressurized metered-dose inhaler (pMDI) and inhaling slowly, the medication can bypass the pharynx and reach the lungs more effectively. This technique helps to eliminate the pharyngeal barrier and improve the delivery of aerosol medication to the desired site of action in the lungs.

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  • 38. 

    The Halolite nebulizer provided teh first generation adaptive aerosol delivery, or AAD, in which dosing is better coordinated with the patient's inhalation such that the inhaled medication has the best opportunity to reach deep into the lungs.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    The Halolite nebulizer introduced the first generation adaptive aerosol delivery (AAD) system, which improves coordination between dosing and the patient's inhalation. This allows the inhaled medication to reach deeper into the lungs, maximizing its effectiveness. Therefore, the statement is true.

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  • 39. 

    Acrylic polymers appear to be more stable than polyvinyl acetate, phthalate (PVAP) and cellulose acetate phthalate (CAP), due to hydrolysis of functional groups in PVAP and CAP

    • True

    • False

    Correct Answer
    A. True
    Explanation
    The statement is true because acrylic polymers are indeed more stable than polyvinyl acetate, phthalate (PVAP), and cellulose acetate phthalate (CAP). This is because PVAP and CAP undergo hydrolysis of functional groups, which can lead to degradation and instability. Acrylic polymers, on the other hand, do not undergo this hydrolysis process and therefore maintain their stability over time.

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  • 40. 

    Methy paraben is more stable at pH 5.5 than at 9.0

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Methyl paraben is a preservative commonly used in cosmetics and personal care products. It is known to be more stable at lower pH levels, such as pH 5.5, compared to higher pH levels like pH 9.0. This means that methyl paraben is less likely to degrade or break down at pH 5.5, making it a more effective preservative in acidic conditions. Therefore, the statement that methyl paraben is more stable at pH 5.5 than at 9.0 is true.

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  • 41. 

    Insoluble polymers are present in latex and pseudolatex colloidal dispersions used to coat tablets and pellets

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Insoluble polymers are indeed present in latex and pseudolatex colloidal dispersions used for coating tablets and pellets. These polymers form a film on the surface of the tablets or pellets, providing protection and controlled release of the active ingredients. This film also improves the appearance and functionality of the coated products. Therefore, the statement is true.

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  • 42. 

    Soybean oil has been used in intravenous fat emulsions to treat comatosed patients and patients suffering from anorexia

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Soybean oil has been used in intravenous fat emulsions to treat comatosed patients and patients suffering from anorexia. This is because soybean oil is a source of essential fatty acids and provides a concentrated form of calories, which can be beneficial for patients who are unable to consume food orally. Intravenous fat emulsions containing soybean oil can help provide necessary nutrients and support the nutritional needs of these patients.

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  • 43. 

    Magnesium stearate and stearic acid are the two most common lubricants utilized by innovator and generic pharmaceutical companies in commercial tablet formulations.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Magnesium stearate and stearic acid are widely used as lubricants in tablet formulations by both innovator and generic pharmaceutical companies. These substances help to prevent sticking of the tablet material to the manufacturing equipment during the compression process. Therefore, the statement that they are the two most common lubricants used in commercial tablet formulations is true.

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  • 44. 

    Aqueous suspensions are heterogeneous systems in which the particles should not settle rapidly.  This is an acceptable property of aqueous suspensions

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Aqueous suspensions are heterogeneous systems where solid particles are dispersed in a liquid medium. One of the desirable properties of these suspensions is that the particles should not settle rapidly. This means that the particles should remain evenly distributed throughout the liquid for a significant amount of time. This property is important because it allows for better stability and uniformity of the suspension, ensuring that the particles are available for desired applications or processes. Therefore, the statement that this is an acceptable property of aqueous suspensions is true.

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  • 45. 

    The Angle of Repose is a physical property of a powder that is used as a measure of flow.  As the Angle of Repose decreases, the flow properties increase.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    The Angle of Repose is a measure of the flow properties of a powder. It refers to the maximum angle at which a pile of powder can maintain its stability without sliding or collapsing. A lower Angle of Repose indicates better flow properties, as it means the powder can flow more easily. Therefore, as the Angle of Repose decreases, the flow properties increase. This statement is true.

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  • 46. 

    Vegicaps are made from HPMC and contain no animal matter and are suitable for both vegetarians and vegans

    • True

    • False

    Correct Answer
    A. True
    Explanation
    The statement explains that Vegicaps are made from HPMC, which is a plant-based material, and do not contain any animal matter. It further states that Vegicaps are suitable for both vegetarians and vegans. Therefore, the correct answer is true as it aligns with the information provided.

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  • 47. 

    High molecular weight hypromellose (HPMC) is used in a matrix tablet to retard the dissolution rates of drugs, whereas low molecular weight hypromellose is used to coat immediate relase tablets.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    High molecular weight hypromellose (HPMC) is a polymer that is commonly used in pharmaceutical formulations. In the case of a matrix tablet, HPMC is used to slow down the dissolution rates of drugs. This is because the high molecular weight of HPMC forms a gel layer around the drug, which controls the release of the drug into the body. On the other hand, low molecular weight hypromellose is used to coat immediate release tablets. This coating helps in protecting the drug and controlling its release, allowing for immediate release of the drug upon ingestion. Therefore, the statement is true.

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  • 48. 

    Medicated powders are powders of mixtures of finely divided particles in dry form for either internal or external use

    • True

    • False

    Correct Answer
    A. True
    Explanation
    This statement is true because medicated powders are indeed mixtures of finely divided particles in dry form that can be used both internally and externally. These powders are commonly used in various medical applications, such as treating skin conditions or as a form of medication for respiratory or digestive issues. The finely divided particles allow for easy application and absorption into the body, making them an effective and convenient form of medication.

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  • 49. 

    Aquaphor, which contains cholesterol, lanolin, and white petrolatum, can be added to an oleaginous ointment base to help form an emulsion; and Aquaphor is able to carry up to about 3x its weight in wate

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Aquaphor, which contains cholesterol, lanolin, and white petrolatum, can be added to an oleaginous ointment base to help form an emulsion. This means that Aquaphor is able to mix with water-based substances and create a stable mixture. Additionally, Aquaphor is capable of carrying up to about three times its weight in water. Therefore, the statement is true.

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  • Mar 21, 2023
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