Book Club Quiz 3 Chap 11-12-PCT Presentation/Webinars

15 Questions | Total Attempts: 54

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Chapter 1-4. Sepsis Handbook


Questions and Answers
  • 1. 
    What is the SIRS Criteria. Check all that apply
    • A. 

      Edema

    • B. 

      Temperature >100.4 degrees Fahrenheit < 96.8 degrees Fahrenheit

    • C. 

      Blood Glucose > 150 mb/ml in absence of diabeties

    • D. 

      HR - > 90bmp

    • E. 

      Respirtory rate > 20 breaths/min

    • F. 

      PaCO2 < 32 mm Hg

    • G. 

      WBC . >12,000/mm3 or > 10% immature bands

    • H. 

      New Onset of Confusion

  • 2. 
    On blood culture systems, only ________ to________ of all blood cultures become positive.
    • A. 

      10-15%

    • B. 

      5-10%

    • C. 

      20-30%

    • D. 

      40-50%

  • 3. 
    C-reactive Protein (CRP) is an acute pahse proten that is released after simulation of inflammatory indicators like IL-6 and IL-8. CRP levels peak after 48 hours of injurious stimulia.
    • A. 

      True

    • B. 

      False

  • 4. 
    True or False:It is recommended that you can use human serum or plasma (Lithium Heparinate) as specimen collections.
    • A. 

      True

    • B. 

      False

  • 5. 
    It is recommended to retest PCT within __________________ hours if any concentrations < 2 ng/mL are obtained.
    • A. 

      3-5

    • B. 

      6-24

    • C. 

      1-3

    • D. 

      24-48

  • 6. 
    The VIDAS B·R·A·H·M·S PCT is intended for use in conjunction with other laboratory findings and clinical assessments to aid in the risk stratification of critically ill patients on their first day of ICU admission for progression to severe sepsis and septic shock. 
    • A. 

      True

    • B. 

      False

  • 7. 
    __________are established rules governing the course of medical treatment in a concise detailed method.
    • A. 

      Order Set

    • B. 

      Antimicrobial Evaluation Criteria

    • C. 

      Protocal

    • D. 

      Lab Standards

  • 8. 
    Check all that apply. Which is not a critical step (s) prior to protocal Implementation
    • A. 

      Obtain Administrative Support

    • B. 

      Evaluate Inter Departmental Interactions

    • C. 

      Establish a formal interactive relationship with the emergency department and the critical care unit

    • D. 

      Indentify champions/unit protocal leaders

    • E. 

      Develop and relay a firm understanding of the goals

    • F. 

      Provide a unit/hospital/system wide education cmpaign

    • G. 

      Obtain clinical support/assistance from the diagnostics company

  • 9. 
    True or False: for any given patient, the PCT assays must be performed on the same type of sample tube?
    • A. 

      True

    • B. 

      False

  • 10. 
    ____________should not be collected in EDTA tubes because it causes a decrease in valuesmeasured.
    • A. 

      Human Serum

    • B. 

      Plasma

    • C. 

      Urine

    • D. 

      Blood Culture

  • 11. 
    True or False: Dr. Roger Bone quoted that, “ Rather than trying to find a magic bullet for cure sepsis, maybe focus should be on early recognition.”
    • A. 

      True

    • B. 

      False

  • 12. 
    Sepsis is the ______ highest cost to Medicare.
    • A. 

      1st

    • B. 

      2nd

    • C. 

      3rd

    • D. 

      4th

  • 13. 
    One characteristic of an ideal biomarker is that it must be an indicator of:
    • Normal physiological processes
    • Pathogenic processes
    • Pharmacological responses to a therapeutic intervention
    What are other characteristics of an ideal biomarker. Check all that apply 
    • A. 

      Affordable

    • B. 

      Measureable and Reproducible

    • C. 

      Automated

    • D. 

      Predicts Clinical Events

    • E. 

      Quickly obtainable and reproducible

    • F. 

      Reflects underlying biological process

  • 14. 
    PCT is found in the C-cells of Thyroid tissue.  In normal synthesis it cleaves to calcitonin.  In the presence of a bacteria insult (systemic bacteria or sepsis) the cleaving does not take place and the entire molecule is spilled into the bloodstream; stimulating other similar cell types to produce PCT; those do not have the ability to synthesize and we see extreme rises in PCT in blood plasma in the first 3-6 hours.  PCT has 20-24 half life. What does half-life mean for PCT? 
    • A. 

      The time it takes to see a change in the patient’s response to medicine

    • B. 

      The time it takes for the molecule to be half of its productive state

    • C. 

      The time it takes to see half of the increase in PCT in the blood

    • D. 

      The time to measure all of the bacteria in the blood

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