Boards Review: Pathology (Hematopoietic, Vascular)

32 Questions | Total Attempts: 107

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Boards Review: Pathology (Hematopoietic, Vascular)

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Questions and Answers
  • 1. 
    What may result from long-term anemia?
    • A. 

      Late diastolic murmur

    • B. 

      Pallor

    • C. 

      Increased heart rate

    • D. 

      Systolic ejection murmur

    • E. 

      Orthostatic hypotension

  • 2. 
    What are the symptoms of macrocytic anemia?
    • A. 

      Glossitis

    • B. 

      Weight loss

    • C. 

      Peripheral neuropathy

    • D. 

      Depression

    • E. 

      Paranoia

  • 3. 
    What causes pernicious anemia?
  • 4. 
    What are 2 specific symptoms of hemolysis?
  • 5. 
    What causes red blood cell hemolysis?
    • A. 

      Mechanical trauma to cells

    • B. 

      Significant blood loss

    • C. 

      Complement induced damage

    • D. 

      Extravascular hemolysis

    • E. 

      Intravascular hemolysis

  • 6. 
    What are the most common forms of thalassemia in the Mediterranean and the US?
  • 7. 
    What are the most common forms of thalassemia in Southeast Asia?
  • 8. 
    What is an X-linked disorder that causes hemolytic anemia with oxidative stress?
  • 9. 
    What causes aplastic anemia?
    • A. 

      Toxic exposure, such as radiation

    • B. 

      Chemicals

    • C. 

      Therapeutic drugs

    • D. 

      Viral infection

    • E. 

      Idiopathic causes

  • 10. 
    What is a myeloproliferative disorder in which there is an increase in circulating RBCs caused by neoplastic clonal proliferation in the marrow?
  • 11. 
    Acute leukemias have a more or less differentiated blast cells circulating than chronic forms?
  • 12. 
    What is a common lab finding in the diagnosis of chronic myelongenous leukemias?
  • 13. 
    What are the characteristics of multiple myeloma?
    • A. 

      Malignant neoplasm of B-lymphocytes

    • B. 

      Affects 50-60 year olds

    • C. 

      Punched out, lytic lesions in bone causing bone pain and fractures

    • D. 

      Hypercalcemia from resorbed bone

    • E. 

      Presence of Bence Jones proteins and renal failure

  • 14. 
    What is the name of the multi-nucleated giant cells found in Hodgkin's lymphoma?
  • 15. 
    What type of lymphoma affecting B-cells has an African and an American form?
  • 16. 
    What is the most common hereditary clotting problem?
  • 17. 
    Vitamin K is required for the synthesis of what clotting factors in the coagulation cascade?
  • 18. 
    What is the most common cause of abnormal bleeding?
  • 19. 
    Thrombocytopenia is a fall in platelets to below what?
  • 20. 
    What occurs after uncontrolled activation of clotting factors and fibinolytic enzymes, often following major tissue damage from burns, sepsis, or complications of pregnancy?
  • 21. 
    Which is the only layer found in capillaries?
  • 22. 
    What types of arteries are affected by atherosclerosis?
  • 23. 
    What are lesions that develop on artery walls that are comprised of macrophages, low-density lipoproteins, fibrin, and smooth muscle. They are usually asymptomatic, complicated plaques?
  • 24. 
    How does arteriosclerosis most probably begin?
  • 25. 
    When oxidized lipids are ingested by MPs, what do they form?
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