Plasma cells are responsible for the production of immunoglobulins, also known as antibodies. Immunoglobulins are proteins produced by plasma cells in response to the presence of foreign substances, such as bacteria or viruses, in the body. These antibodies help to identify and neutralize these foreign substances, playing a crucial role in the immune response. Mast cells, fibroblasts, macrophages, and mesenchymal cells are all important components of the immune system, but they do not directly produce immunoglobulins.