Block 13 Brain Tumor MCQ's

9 Questions | By Chachelly | Last updated: Feb 22, 2013

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Questions and Answers

1.

A 29-year-old woman presents with tinnitus and a sensori-neural hearing loss on the left. The excised mass was seen near the cerebellopontine angle, arising from the left VIIIth nerve. Histology showed a tumor comprising of benign spindle shaped cells with Antoni A and Antoni B type of patterns. What is your diagnosis?

Discuss
- A.
  
  Ependymoma
- B.
  
  Astrocytoma
- C.
  
  Schwannoma
- D.
  
  Medullaoblastoma
- E.
  
  Glioblastoma multiforme
2.

A young boy is brought to the clinic. He appears quite small for his age and complains of not being able to see as well as he used to. Visual field examination reveals a bi-temporal hemianopsia. You suspect a tumor located near the…

Discuss
- A.
  
  Pituitary gland and stalk
- B.
  
  Calcarine sulcus
- C.
  
  Parieto-occipital sulcus
- D.
  
  Nucleus of cranial nerve III
- E.
  
  Pineal gland
3.

An MRI reveals a large tumor occupying much of the left parietal lobe of a middle aged female patient. An attending resident looks at the image and states that it’s the most common kind of intracranial tumor with, unfortunately, typically a poor prognosis. Such tumors are called…

Discuss
- A.
  
  Schwannomas
- B.
  
  Oligodendrogliomas
- C.
  
  Meningiomas
- D.
  
  Astrocytomas
- E.
  
  Ependymomas
4.

A 58-year-old man was brought to the emergency room after having a seizure. On examination he has a right hemiparesis. An MRI of the brain shows a tumor involving the left fronto-temporal lobes with a large amount of surrounding edema. A brain biopsy is planned. He is admitted to the hospital and started on phenytoin and hyperosmolar fluids i.v. The following morning he is found somnolent and his left pupil is large and unreactive to light. The most likely cause of his pupillary findings is due to:

Discuss
- A.
  
  Subfalcine herniation causing a stroke through compression of the anterior cerebral artery
- B.
  
  An unwitnessed seizure
- C.
  
  An allergic reaction to phenytoin
- D.
  
  Increased edema leading to uncal herniation and compression of CNIII
- E.
  
  Brainstem compression due to tonsillar herniation
5.

A 29-year-old woman with a family history of renal cell carcinoma, presents with gait disturbance and blurred vision; P.E.: has retinal hemangiomas, nystagmus, cerebellar ataxia. An MRI of the brain was ordered. Extracerebral manifestations associated to the main brain pathology in this patient are:

Discuss
- A.
  
  Secondary polycythemia
- B.
  
  Syringomyelia
- C.
  
  Adrenal hyperplasia
- D.
  
  Cardiac myxoma
- E.
  
  Polycystic kidneys
6.

A 73 year-old-woman attends the clinic complaining of unilateral tinnitus and unilateral hearing loss. On physical examination there is discrete facial weakness and loss of corneal reflex on the same side as the symptoms. Where would the anatomic location be most likely, in order to produce the signs and symptoms in this patient?

Discuss
- A.
  
  Frontal cortex
- B.
  
  Anterior pituitary
- C.
  
  Anterior horn of upper spinal cord
- D.
  
  Cerebellopontine angle
- E.
  
  Lateral ventricle
7.

The following list of primary malignancies accounts for the majority of metastatic brain tumors:
- A.
  
  Lung, breast, melanoma
- B.
  
  Testis, ovary, melanoma
- C.
  
  Lung, prostate, uterus
- D.
  
  Pancreas, melanoma, ovary
- E.
  
  Salivary gland, ovary, testis
8.

Which of the following criteria are used for the diagnosis of oligodendroglioma?
- A.
  
  Pleomorphic glial cells, high mitotic activity, pseudopalisading, and vascular endothelial proliferation
- B.
  
  Cyst with mural nodule, pilocytic astrocytes with Rosenthal fibers
- C.
  
  Well circumscribed nodule, whorls of spindle-shaped cells, and psammoma bodies
- D.
  
  Well circumscribed nodule, “fried-egg” cells, and chicken-wire capillary pattern
9.

Pathomorphologic criteria for diagnosis of meningioma are:
- A.
  
  Well circumscribed nodule, whorls of spindle-shaped cells, and psammoma bodies.
- B.
  
  Cyst with mural nodule, pilocytic astrocytes with Rosenthal fibers.
- C.
  
  Well circumscribed nodule, “fried-egg” cells, and chicken-wire capillary pattern.
- D.
  
  Pleomorphic glial cells, high mitotic activity, pseudopalisading, and vascular endothelial proliferation.

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