Can You Cass This Antibiotics Trivia Quiz?

23 Questions | By Nathanj37 | Last updated: Mar 17, 2022 | Total Attempts: 93

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A semi-comprehensive quiz designed to test the user on the aspects of antibiotics that are considered clinically important

Questions and Answers

1.

Which of the following fluoroquinolones cannot be used for a UTI?
- A.
  
  Ciprofloxacin
- B.
  
  Levofloxacin
- C.
  
  Moxifloxacin
2.

Which of the following fluoroquinolones displays slight activity against Pseudomonas aeruginosa?
- A.
  
  Ciprofloxacin
- B.
  
  Levofloxacin
- C.
  
  Moxifloxacin
- D.
  
  Cipro and Levo
- E.
  
  Levo and Moxi
3.

Which of the following agents is MRSA most likely to be resistant to?
- A.
  
  Vancomycin
- B.
  
  Clindamycin
- C.
  
  Bactrim
- D.
  
  Linezolid
- E.
  
  Doxycycline
4.

Describe the killing characteristic of vancomycin
- A.
  
  Bacteriostatic
- B.
  
  Bacteriocidal
- C.
  
  Bacteriostatic or bactericidal
5.

Describe the killing characteristic of vancomycin
- A.
  
  Time-dependent
- B.
  
  Concentration-dependent
- C.
  
  Both of the above
6.

What indication DOES NOT have a vancomycin-associated trough of 15-20 mcg/mL?
- A.
  
  Meningitis
- B.
  
  Pneumonia
- C.
  
  Cellulitis
- D.
  
  Osteomyelitis
- E.
  
  Endocarditis
7.

Which of the following agents is bound by pulmonary surfactant?
- A.
  
  Daptomycin
- B.
  
  Penicillin V
- C.
  
  Vancomycin
- D.
  
  Quinupristin
- E.
  
  Sulfamethoxazole
8.

Which of the following antimicrobials has the greatest potential to interact with warfarin?
- A.
  
  Bactrim
- B.
  
  Fluconazole
- C.
  
  Metronidazole
- D.
  
  Two of the above
- E.
  
  All of the above
9.

Which of the following agents is the WORST choice to treat CAP?
- A.
  
  Zosyn
- B.
  
  Doxycycline
- C.
  
  Ciprofloxacin
- D.
  
  Augmentin
10.

An appropriate response to treating Vancomycin-induced Red Man Syndrome would be:
- A.
  
  Diphenhydramine
- B.
  
  Acetaminophen
- C.
  
  Slowing the infusion rate on subsequent infusions
- D.
  
  Two of the above
- E.
  
  All of the above
11.

Aspiration pneumonia treatment requires additional coverage of what organisms?
- A.
  
  Anaerobes
- B.
  
  Fungi
- C.
  
  Gram negative
- D.
  
  Enterococci
12.

Which of the following is not an option when treating C diff colitis?
- A.
  
  IV Metronidazole
- B.
  
  PO Metronidazole
- C.
  
  IV Vancomycin
- D.
  
  PO Vancomycin
13.

Which aminoglycoside has less sites available for modification, and thus additional coverage of otherwise AG-resistant pathogens?
- A.
  
  Neomycin
- B.
  
  Tobramycin
- C.
  
  Amikacin
- D.
  
  Gentamycin
- E.
  
  Colistin
14.

What is the most common mechanism of resistance found in Pseudomonas aeruginosa?
- A.
  
  Many efflux pumps
- B.
  
  Unusually thick cell wall
- C.
  
  Drug-inactivating enzymes
- D.
  
  Target site changes
- E.
  
  MecA gene expression
15.

What is the proper dose of azithromycin for MAC prophylaxis in AIDS patients?
- A.
  
  500 mg today, then 250 mg daily
- B.
  
  250 mg daily
- C.
  
  1200 mg weekly
- D.
  
  3000 mg monthly
16.

Which of the following agents has a potential to cause thrombocytopenia, chiefly correlated with use greater than 28 days?
- A.
  
  Vancomycin
- B.
  
  Tobramycin
- C.
  
  Tigecycline
- D.
  
  Bactrim
- E.
  
  Linezolid
17.

What is the most relevant pathogen that tigecycline lacks coverage of?
- A.
  
  Pseudomonas aeuruginosa
- B.
  
  Enteroccus Faecium
- C.
  
  MRSA
- D.
  
  Acinetobacter
- E.
  
  Mycobacterium pneumoniae
18.

Levofloxacin has a boxed warning concerning:
- A.
  
  QT prolongation
- B.
  
  Seizures
- C.
  
  Hepatotoxicity
- D.
  
  Tendon rupture
- E.
  
  More than one of the above
19.

Ciprofloxacin has a category X drug interaction with which of the following agents?
- A.
  
  Tizanidine
- B.
  
  Amiodarone
- C.
  
  Warfarin
- D.
  
  Atorvastatin
- E.
  
  Phenytoin
20.

How many oral agents exist that could effectively treat MRSA as monotherapy?
- A.
  
  3
- B.
  
  4
- C.
  
  5
- D.
  
  6
- E.
  
  7
21.

Which of the following agents has the greatest potential for causing C diff colitis?
- A.
  
  Linezolid
- B.
  
  Tigecycline
- C.
  
  Clindamycin
- D.
  
  Ampicillin
- E.
  
  Ertapenem
22.

What is the purpose of cilastin in Primaxin?
- A.
  
  Prolong half-life of imipenem
- B.
  
  Prevent a toxicity of imipenem
- C.
  
  Lower seizure potential of imipenem
- D.
  
  Provide synergistic antimicrobial activity
- E.
  
  Prevent metabolism of imipenem
23.

What additional pathogen is not a typical finding in osteomyelitis, but appears as a possibility in patients who admit to IV drug use?
- A.
  
  MRSA
- B.
  
  Pseudomonas aeruginosa
- C.
  
  Staph saprophyticus
- D.
  
  HIV
- E.
  
  Neisseria spp