An atom consists of three primary components: protons, neutrons, and electrons. The nucleus, located at the center of the atom, contains protons, which are positively charged, and neutrons, which are neutral. Surrounding the nucleus are electrons, which carry a negative charge and occupy various energy levels. This structure is fundamental to the properties of elements and their interactions in chemical reactions. Other options, such as photons or positrons, do not constitute the main parts of an atom, making the combination of nucleus, protons, neutrons, and electrons the correct answer.