UTIs and antibiotic therapy
Mainly occur in adult non-pregnant women, cleared up with antibiotics
Associated with anatomical / functional abnormalities which predispose patient to UTIs. Can be difficult to clear up with antibiotics.
Associated with anatomical / functional abnormalities which predispose patient to UTIs. Are cleared up with antibiotics
Have a high risk of serious complications and treatment failure
Usually acute
Type 1 Pilli in E. coli
Type 2 Pilli in E.coli
Pyelonephritis associated pilli in E.coli
Type 1 pilli in coagulase negative staphylococci
Pyelonephritis associated pilli in enterococci
E.coli
Coagulase negative staphylococci
Enterococci
Other gram negative organisms
Cephalexin
Trimethoprim
Amoxycillin + clavulanate
Nitrofurantoin
A suicide inhibiter which breaks down beta lactam rings and a compound that inhibits protein synthesis
Two compounds that inhibit nucleic acid synthesis
Penicillin and a suicide inhibitor which breaks down penicillinase
A compound to inhibit cell wall synthesis and another to competitively inhibit the PABA protein
Bind to an inhibit enzymes that catalyse the linkage of peptidoglycan cell walls
Bind to an inhibit enzymes that catalyse the linkage of lipopolysaccharide cell walls
Disrupt cell membrane function
Inhibit protein synthesis
Competitively inhibit PABA enzymes
Trimethoprim
Nitrofurantoin
Amoxycillin and clavulanate
Cephalexin
Streptomycin
Gram positive bacteria, where bacteriostatic drugs have been used.
Gram positive bacteria, where bacteriostatic drugs are not in use.
Gram negative bacteria, where bacteriostatic drugs have been used
Gram positive bacteria, where bacteriostatic drugs are not in use.
Sensitive bacteria (depending on certain drug), where bacteriostatic drugs are not in use.
Penicillins
Cephalosporins
Cephamycins
Carbapenems
Monobactams
Smaller side chains created to allow drugs to pass through the porins in the peptidoglycan layer.
Altered structure to allow penicillins to attack lipopolysaccharides
Added compound to attack Beta lactamase enzymes
Added compound to block cell wall formation
Penicillin
Ampicillin
Amoxicillin
Carbonicillin
Benzyl penicillin