Utis And Antibiotic Therapy

13 Questions | By Maddi123 | Last updated: Mar 20, 2022 | Total Attempts: 57

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UTIs and antibiotic therapy

Questions and Answers

1.

What are complicated UTIs?
- A.
  
  Mainly occur in adult non-pregnant women, cleared up with antibiotics
- B.
  
  Associated with anatomical / functional abnormalities which predispose patient to UTIs. Can be difficult to clear up with antibiotics.
- C.
  
  Associated with anatomical / functional abnormalities which predispose patient to UTIs. Are cleared up with antibiotics
- D.
  
  Have a high risk of serious complications and treatment failure
- E.
  
  Usually acute
2.

Which virulence factors are associated with more severe infection?
- A.
  
  Type 1 Pilli in E. coli
- B.
  
  Type 2 Pilli in E.coli
- C.
  
  Pyelonephritis associated pilli in E.coli
- D.
  
  Type 1 pilli in coagulase negative staphylococci
- E.
  
  Pyelonephritis associated pilli in enterococci
3.

80% of UTIs are caused by?
4.

What causes ten percent of Community-acquired UTIs?
- A.
  
  E.coli
- B.
  
  Coagulase negative staphylococci
- C.
  
  Enterococci
- D.
  
  Other gram negative organisms
5.

Which of these antibiotics can't be used in pregnant women?
- A.
  
  Cephalexin
- B.
  
  Trimethoprim
- C.
  
  Amoxycillin + clavulanate
- D.
  
  Nitrofurantoin
6.

What are amoxycilin and clavulanate?
- A.
  
  A suicide inhibiter which breaks down beta lactam rings and a compound that inhibits protein synthesis
- B.
  
  Two compounds that inhibit nucleic acid synthesis
- C.
  
  Penicillin and a suicide inhibitor which breaks down penicillinase
- D.
  
  A compound to inhibit cell wall synthesis and another to competitively inhibit the PABA protein
7.

How do Beta lactam antibiotics work?
- A.
  
  Bind to an inhibit enzymes that catalyse the linkage of peptidoglycan cell walls
- B.
  
  Bind to an inhibit enzymes that catalyse the linkage of lipopolysaccharide cell walls
- C.
  
  Disrupt cell membrane function
- D.
  
  Inhibit protein synthesis
- E.
  
  Competitively inhibit PABA enzymes
8.

Which of these antibiotics can be used for treatment of acute cystitis in pregnant women?
- A.
  
  Trimethoprim
- B.
  
  Nitrofurantoin
- C.
  
  Amoxycillin and clavulanate
- D.
  
  Cephalexin
- E.
  
  Streptomycin
9.

Where can Beta lactam antibiotics be used?
- A.
  
  Gram positive bacteria, where bacteriostatic drugs have been used.
- B.
  
  Gram positive bacteria, where bacteriostatic drugs are not in use.
- C.
  
  Gram negative bacteria, where bacteriostatic drugs have been used
- D.
  
  Gram positive bacteria, where bacteriostatic drugs are not in use.
- E.
  
  Sensitive bacteria (depending on certain drug), where bacteriostatic drugs are not in use.
10.

Which of these antibiotics are Beta Lactam antibiotics?
- A.
  
  Penicillins
- B.
  
  Cephalosporins
- C.
  
  Cephamycins
- D.
  
  Carbapenems
- E.
  
  Monobactams
11.

How were extended spectrum penicillins produced?
- A.
  
  Smaller side chains created to allow drugs to pass through the porins in the peptidoglycan layer.
- B.
  
  Altered structure to allow penicillins to attack lipopolysaccharides
- C.
  
  Added compound to attack Beta lactamase enzymes
- D.
  
  Added compound to block cell wall formation
12.

Which enzyme conferred resistance against penicillin?
13.

Which of these are extended spectrum penicillin?
- A.
  
  Penicillin
- B.
  
  Ampicillin
- C.
  
  Amoxicillin
- D.
  
  Carbonicillin
- E.
  
  Benzyl penicillin