Robbins Gen Path - Genetics

10 Questions | By Arayti | Last updated: Mar 21, 2022 | Total Attempts: 94

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Questions based on Robbins and Cotran

Questions and Answers

1.

Which term best defines the loss or gain of whole chromosomes?
- A.
  
  Point mutation
- B.
  
  Genome mutation
- C.
  
  Missense mutation
- D.
  
  Frameshift mutation
- E.
  
  Chromosome mutation
2.

Which term best defines the rearrangement of genetic material that gives rise to visible structural changes in the chromosome?
- A.
  
  Point mutation
- B.
  
  Genome mutation
- C.
  
  Frameshift mutation
- D.
  
  Chromosome mutation
- E.
  
  Genome rearrangement
3.

Which term best defines the insertion or deletion of one or two base pairs in the DNA strand, leading to alterations in the reading frame?
- A.
  
  Point mutation
- B.
  
  Genome mutation
- C.
  
  Frameshift mutation
- D.
  
  Missense mutation
- E.
  
  Chromosome mutation
4.

Which term best defines a point mutation that alters the code in a triplet of bases, leading to the replacement of one amino acid by another?
- A.
  
  Missense mutation
- B.
  
  Frameshift mutation
- C.
  
  Genome mutation
- D.
  
  Loss of function mutation
- E.
  
  Gain of function mutation
5.

Which type of mutation almost always affects guanine and cytosine nucleotides?
- A.
  
  Missense mutation
- B.
  
  Frameshift mutation
- C.
  
  Loss of function mutation
- D.
  
  Gain of function mutation
- E.
  
  Trinucleotide repeat mutations
6.

Abnormal _______________ may result from mutations affecting introns or splice junctions, or both.
- A.
  
  Transcription
- B.
  
  Translation
- C.
  
  TRNA processing
- D.
  
  MRNA processing
- E.
  
  DNA processing
7.

Which term best defines the full expression of both alleles of a pair in the heterozygote?
- A.
  
  Codominance
- B.
  
  Pleotropism
- C.
  
  Complete penetrance
- D.
  
  Incomplete penetrance
- E.
  
  Genetic homozygosity
8.

When a single mutant gene leads to many end effects, this process is defined as:
- A.
  
  Hemizygosity
- B.
  
  Codominance
- C.
  
  Pleiotropism
- D.
  
  Genetic homozygosity
- E.
  
  Genetic heterogeneity
9.

Which term best defines mutations at several genetic loci that produce the same trait?
- A.
  
  Genetic homozygosity
- B.
  
  Genetic heterogeneity
- C.
  
  Pleotropism
- D.
  
  Hemizygosity
- E.
  
  Autosomal recessive disorders
10.

When an individual inherits a mutant gene but is phenotypically normal, this condition is best defined as:
- A.
  
  Dominant disorder
- B.
  
  Recessive disorder
- C.
  
  Partial penetrance
- D.
  
  Complete penetrance
- E.
  
  Incomplete penetrance

Related Topics

DNA
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